MOCEL - Molecular & Cellular Biology Dept - University of Geneva
@mocel.bsky.social
📤 49
📥 54
📝 1
From molecules to diseases
https://mocel.unige.ch/
New article from Emmanuel Levy'Lab : they discovered that missense mutations in homomeric proteins can trigger supramolecular assembly but, remarkably, these folded protein assemblies are not toxic. A testament to cellular robustness!
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4 months ago
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Emmanuel Levy's lab
4 months ago
Years ago we discovered that missense mutations in homomeric proteins often induces their supramolecular assembly, as in the 📽️👇 - Are such aberrant assemblies of *folded* proteins toxic? Surprisingly, NO. Cells are amazingly robust systems! Paper now online
@molsystbiol.org
doi.org/10.1038/s443...
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Biology-UNIGE
4 months ago
👏 Congratulations
@elevylab.bsky.social
for your latest publication in
@molsystbiol.org
: Mutation-induced filaments of folded proteins are inert and non-toxic in a cellular system
@mocel.bsky.social
#UNIGE
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Paul & Virginie - Centriole Lab
4 months ago
🧬 New tool for U-ExM! HAK-Actin is now available from Spirochrome → a reliable probe to label actin filaments in expansion microscopy. Check it out at Spirochrome!
#UExM
#Actin
#Cytoskeleton
#SuperResolution
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Biology-UNIGE
4 months ago
🏅Congratulations to Emeritus Prof. Ueli
#Schibler
for receiving the
#Kappers
Medal from the
#EBRS
: the Society’s highest honor, awarded for outstanding contributions to biological rhythms research
@sciencesunige.bsky.social
@mocel.bsky.social
#UNIGE
ebrs-online.org/index.php/abou
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Biology-UNIGE
5 months ago
Congratulations
@elevylab.bsky.social
and collaborators for your latest publication in Cell 👏 and welcome to BlueSky 🦋@mocel.bsky.social
@sciencesunige.bsky.social
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Ana Coelho Almeida
6 months ago
🔎New preprint! We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture. Big thanks to
@ivanagasic.bsky.social
and team! Link below for all
#cytoskeleton
&
#spheroid
enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
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Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability
Alpha- and beta-tubulin heterodimers dynamically assemble into microtubules, key cytoskeletal elements involved in intracellular trafficking, cell adhesion and division. The availability of free tubul...
https://www.biorxiv.org/content/10.1101/2025.07.28.667019v1
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Biology-UNIGE
5 months ago
Congratulations Emeritus Prof.
#Martinou
from
@mocel.bsky.social
and collaborators for your latest publication in
#Nature
#Metabolism
👏
rdcu.be/eASgF
👉 Check
#UNIGE
press release:
www.unige.ch/medias/en/20...
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d-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1
Nature Metabolism - Zangari et al. show that d-cysteine targets NFS1, thus affecting Fe–S cluster biogenesis and impairing tumour growth.
https://rdcu.be/eASgF
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Ivana Gasic
11 months ago
Arresting mitosis with visible light! Brilliant Victoria von Glasenapp from the Gotta and Winssinger labs @UNIGE develops a cool photo-caged PLK1 inhibitor, which we deploy in 3D spheroids to control mitosis with exquisite spatio-temporal precision. Check out the original article:
lnkd.in/eTnzy5Nc
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Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability - Nature Communications
Light is a powerful tool for controlling biological processes. Here, the authors demonstrate its use to modulate inhibitor activity and diffusion, enabling precise control of cell division in multicel...
https://lnkd.in/eTnzy5Nc
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Armando Rubio Ramos
10 months ago
Being part of the Pint of Science Geneva team is an absolute blast! 🚀 We’re working hard (and having a little fun too 😁) to bring amazing science talks this 19-21th May. 📌SAVE THE DATE: 19-21 May 2025 🧬
#Science
#PintofScience
#Geneva
pintofscience.ch
@pintofscience.ch
@marinebrunet.bsky.social
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MOCEL - Molecular & Cellular Biology Dept - University of Geneva
Armando Rubio Ramos
11 months ago
Having a good time in the LS2 annual meeting
@lifesciswitzerland.bsky.social
😊☺️
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