I joined the Sohal lab with one major hypothesis: psychedelic drugs can be powerful psychiatric treatments, depending on underlying neurobiology. Indeed, psilocybin restored cognitive flexibility in one circuit model of dysfunction, but not another! Then, we had to find out how! 🧠🍄🧪

New preprint led by @christineliu.art! How do psychedelics improve cognitive flexibility? Psilocybin prevents inflexibility caused by aberrant mesocortical error signaling (but not inflexibility due to other mechanisms); this is tied to plasticity of PFC-MD neurons: www.biorxiv.org/content/10.6...

For the last 5 years, my lab has focused on developing mutational scanning methods and learning how to answer specific questions in protein biology. @matthewkhoward.bsky.social and I wrote a review on experimental decisions and future directions for our nascent field! doi.org/10.1146/annu...

Happy to announce that I received tenure! This is all down to the brilliant team I get to work with every day and my collaborators and supportive colleagues. Now UCSF can’t get rid of me…

I am delighted to share that my newest manuscript and the first of my postdoc in the Marqusee and Bustamante labs, “A detailed molecular picture of protein folding during active translation”, is now on the BioRXiv! (1/n) www.biorxiv.org/content/10.6...

A proposed OMB rule would allow political appointees to override scientific peer review when making federal research funding decisions. For ECRS, this isn’t abstract. It affects training, jobs, and future discoveries. Read more ⬇️ sciencepolitics.org/2026/06/05/w... From us @snapcoalition.org

Delighted to share our lab's latest (w/ inimitable @genophoria.bsky.social) in final form at @nature.com. Enormous lift by Sean Wang, @palindromephd.bsky.social & @martyyang.bsky.social to address extensive & constructive reviewer comments & see this through. (1/n) www.nature.com/articles/s41...

The Phenotypic Landscape of a Circadian Clock https://www.biorxiv.org/content/10.64898/2026.04.23.720472v1

1/28 How do you optimize a dynamic protein property that emerges from multiple states? Our finally published paper in @NatureComms takes on one of the hardest problems in protein engineering with phage assisted evolution: evolving allosteric switches🧵

I'm ecstatic to share that I'm joining the @diffuseproject.bsky.social (diffuse.science) full-time as Scientific Program Director at @asterainstitute.bsky.social .

Rebecca is starting her lab as a UCSF Sandler fellow in August 2026; folks at #Dros26 interested in host-parasitoid interactions should try to catch her at the meeting to find out about available positions: www.tarnopollab.org/people

Check out the new, improved version of our Mutation Browser preprint. We worked with a team from the Broad including their outreach office, a great summer intern, and the G2P project to add a new browser panel that maps mutations onto yeast protein structures! www.biorxiv.org/content/10.1...

Congrats @jeromics.bsky.social on getting your facs model out - we literally use it all the time and was so happy to work together with you on it!

Of course, I am over the moon with happiness that @veatchlab.bsky.social won the 2026 Agnes Pockels Award from the @biophysicalsoc.bsky.social. Moreover, TWO students in Sarah's lab won poster awards at the BPS Meeting! What a year for the Veatch Lab! #bps2026

A wonderful first for me at the upcoming @biophysicalsoc.bsky.social meeting in SF is having many lab members present! See 6 brilliant graduate students postdocs from the lab present talks and posters on how they are pushing the boundaries of technology and mechanistic membrane protein biology

If you’re attending #BPS2026, there are several opportunities to hear about ongoing projects in the Starbird lab. Looking forward to seeing everyone at BPS!

Awesome seminar today by UCSF's @willowcoyote.bsky.social! He is not afraid to blaze his own trail, redefining paradigms along the way!

Excited to share emerging studies in the lab and learn from all the brilliant scientists at uw Madison!

Our paper is (finally) out in Cell today! CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis www.cell.com/cell/fulltex... Great collaborative effort - read more from first author @asamelson.bsky.social below:

Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him. White. Hot. Rage.

NEW pub in @science.org 🥳 Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life? For over 15 years, #phylogenomic studies have been divided. We provide new evidence suggesting that... 🔗: www.science.org/doi/10.1126/...

When people celebrate the individual genius of folks in science, they should also mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)

Zara was one of the best people I've crossed paths with in this career, in this life. A fissure has opened with her departure, and I will miss her terribly.

Zara was an inspiration. We never met in person but became friends through Leading Edge. She zealously advocated for her ideals, but was also passionate about helping others realize why they should too. Her loss is gutting & the world is the worse for it. RIP, I'll do my best to continue the fight.

We are all better because of the energy, inspiration, brilliance, and tenacity that Zara was. A bright light, role model, advocate & snarky tweeter... everything I needed in a person when I was navigating dark times when we met in 2021. You will be missed deeply, Zara, but never forgotten ❤️

Zara was a great inspiration and mentor... Its really sad the excellent often leave us too soon... You will be missed Zara 💕

Zara will be missed. Such terrible news.

Zara Weinberg was a brilliant, loving, and beautiful woman. She inspired everyone who she interacted with, and always strived to make the world a better place for everyone. Tho the world is a little less bright today without her, her memory will always be a blessing. She was truly one of the best.

Truly one of the best. We worked on various initiatives/wrote a paper together, and had the best conference meet ups. She was a bold and tireless advocate for change. Last time we met, we had a great time trying new cuisine and imagining a future that’s so different for trainees than we experienced.

Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed. She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.

We are #hiring for a Tenure Track Assistant Professor position in the Department of Molecular&Cellular Physiology (med.stanford.edu/mcp.html) at @stanfordmedicine.bsky.social. Please apply or forward the opportunity to anybody who might be interested. facultypositions.stanford.edu/en-us/job/49...

Today I am so pleased to present our work on how chromatin remodelers affect mesoscale chromatin organization. www.science.org/doi/10.1126/...

I love writing spontaneous and unsolicited reviews. I would be thrilled folks did it to me too! I think it gets the heart of what we do science for - giving and getting feedback to get closer to the ‘truth’! Otherwise why post a preprint if you don’t want people to read and respond?

Check out MitoScribe in our new preprint led by Linhan Wang: www.biorxiv.org/content/10.1... It's an analog molecular recorder that uses neutral base edits to the mitochondrial genome to store information about historical signaling in a cell. Single cell resolution at scale (see next post)!

1st day of classes went well for this associate professor! I’ll ride this tenure/promotion wave for another week. I’m teaching a new chemical biology class this semester. Excited to bring computational chemistry topics & hands-on activities in the computer lab. Also still masking this semester!

Latest pre-print from our lab is out. Great work by @alexbendel.bsky.social and team. Full deep mutational scan of an entire human protein interaction domain family 2M quantitative measurement of protein-protein interaction -> deep learning model to predict PPI from sequence More details 👇

Congrats Kevin Allan, Jesse Zhan, @tymillerlab.bsky.social, @tesarlab.bsky.social, et al It was fun to do some super-resolution microscopy to help look into how a cell matures, all while sending a lot of spooky faces to Paul and Kevin since, unlike these Sox6 ko cells, I have yet to mature 😱😱😱😱😱

I am happy to finally share this preprint of my PhD project in @guillaumediss.bsky.social lab at the FMI in Basel. We used ddPCA to map the genetic architecture of the entire human bZIP interaction network. www.biorxiv.org/content/10.1... Thanks to all our co-authors for the great collaboration!

I got to share a bit about Indigenous values in chemistry on this pod! Thanks @nature for the feature and joining some an amazing list of ChangeMakers!

Assistant Professor position in Traditional Ecological Knowledge at Stanford University. Applications due Sept 30, 2025 facultypositions.stanford.edu/en-us/job/49...

ProDomino is a machine learning-based method that predicts domain insertion sites and helps guide the engineering of functional multi-domain proteins. www.nature.com/articles/s41...

Awesome work from @jingyour.bsky.social, @hjp.bsky.social and a lil bit us! New stats framework for mutational scanswhere we measure multiple phenotypes like expression & activity. Jingyou is able to pull out immediately patterns that took us otherwise weeks to months data digging. Amazing work!

So lucky to have the brilliant @jingyour.bsky.social joining the lab as a postdoc! It’s been inspiring collaborating the last couple years and I can’t wait to see the extraordinary things she’ll do :)

Super proud of my first student, @jingyour.bsky.social! Well done! Looking forward to the amazing work you will do in the future 🥲 bsky.app/profile/jing...

Thrilled to share that I just successfully defended my PhD! Thanks to my committee, collaborators, and everyone who’d supported me throughout my seven years at UCLA. A special thank you to my PI Harold for his incredible mentorship! @hjp.bsky.social

🧪🖥️🧬 It's here!! Our second MPRA, which is totally different from the first. For starters, there's no human sequences anywhere! Instead there's marsupials, wolves, pandas and a lot of hard work from lab members past & present, chief amongst them @navya-shukla.bsky.social (looking for a postdoc btw)

Officially tenured. Thank you to all the mentors who guided me, and to the trainees who made this possible with your ideas, hard work, and scientific joy.

Very excited to have this work out by @jeromics.bsky.social ! Please check it out. I think my favorite story from the supplement is how impactful normalization can be in this context. bsky.app/profile/jero...

Check out Jerome's paper! As we push the boundaries of DMS, it is critical that we develop robust ways to score variant effects--and he is doing just that. Excited to put this to use in our upcoming GPCR-DMS endeavors :)

Check out @jeromics.bsky.social @hjp.bsky.socials recent facs based model for dms studies!!!