We're hiring at NTU SBS, Singapore. Tenure-track faculty position in Biomedical Data Science (computational biology, AI in biology, bioinformatics). Great infrastructure, great place to do science. Please share. apply.ap1.interfolio.com/119013

Registration for MSS26 in Melbourne will close next Monday - we still have a few tickets available, and an amazing line-up of speakers across all areas of variant effects work, so if you were on the fence, check out our program and then smash that "Register now" button! www.mss2026.org

Leipzig U and the MPI for Evolutionary Anthropology (MPI-EVA) have an open faculty position (W2) in evolutionary population genetics! This position is tenured and comes with generous core funding. We are eager to welcome a new colleague! Deadline March 11. www.uni-leipzig.de/en/newsdetai...

An international team, including Associate Professor Davis McCarthy and colleagues, has developed a breast screening artificial intelligence (AI) tool that estimates a woman’s risk of developing breast cancer more accurately than current methods. Find out more: www.svi.edu.au/news-events/...

Threaded below for your convenience, if you're one of those people who does not live online on weekends! (Also my hair looks great thanks for asking)

Job alert: open position for a Professor or Associate Professor of Computational Genomics in Health and Disease at University College London. Based in the Department of Genetics, Evolution and Environment of UCL, and UGI, and funded by the UCL Health Strategy. www.ucl.ac.uk/work-at-ucl/... 🧪

Finally, today's offering! www.biorxiv.org/content/10.6... This began life as a very different project which failed because we couldn't agree on defining eqtl sharing across cohorts. So two young members of the lab dug deeply into this - first @ijbeasley.bsky.social, then @patrickgibbs.bsky.social

Second, this piece, which is more reflexive than our usual. I cannot claim much credit for the work @paikusuma.bsky.social writes about here, but being even just a little part has been a huge privilege. doi.org/10.5281/zeno...

First, a couple of weeks ago: www.biorxiv.org/content/10.6... Single cell RNAseq on blood from 200 donors across 4 sites in Indonesia spanning regional axes of genetic and environmental diversity. This is one of very few scRNA data sets from the Global South, including urban and rural settings.

We've preprinted three very different manuscripts in the last two weeks and I'm sitting at the salon getting my hair dyed hot pink so I hope you're all ready for some tweetorials (or whatever we're calling them these days)

Power is a major confounder in the analysis of cross-ancestry 'portability' in human eQTLs https://www.biorxiv.org/content/10.64898/2026.02.26.708346v1

We posted a preprint on Zenodo: “The important role of community engagement in genetic research: Lessons from the study of Bornean contemporary hunter–gatherers” (zenodo.org/records/1875...). We present a practical, field-tested approach to doing genomics with Indigenous communities. 1/

Hi yes I will have more to say about this in a few hours but please enjoy this paper. It's been a huge labour of love and effort for the last four years, and a significant part of our research efforts, and I'm so so so thrilled it's finally ready to share. Tldr: scRNA-seq in Indonesia hard but fun

Just discovered the wonderful covers of 'Genes to Cells', the journal of the Molecular Biology Society of Japan @mbsj-official.bsky.social – absolutely beautiful! here some examples inspired by mitosis, CRISPR, the DNA helix, and plant pigments

Making figures for this paper be like

I've started my own lab 🎉 PhD/postdoc positions available - reach out if curious about cerebellum evo-devo and autism spectrum disorders. We’re based at Uni Tartu, Institute of Genomics (home to Estonian Biobank), and funded by @simonsfoundation.org @embo.org, and the Estonian Research Council.

What's the German word for 'desperately avoiding my email because of all the blown deadline reminders in there so actually getting some stuff done'?

Yes, ungroup(), I definitely want you to insist that NK comes before Naive when I sort alphabetically because you are so into ASCII sorting that no other options exist... Anyhow, another tiny bug squashed. We'll finish this paper yet.

Choose your adventure at Lorne Genome: https://www.lornegenome.org/afternoon-activities 🏄‍♀️: 𝐋𝐞𝐚𝐫𝐧 𝐭𝐨 𝐬𝐮𝐫𝐟 and wipe out in front of your PI/students 🥾: 𝐇𝐢𝐤𝐞 𝐭𝐨 𝐰𝐚𝐭𝐞𝐫𝐟𝐚𝐥𝐥𝐬 (pretend months in the lab haven't destroyed your cardio) 🍷: 𝐖𝐢𝐧𝐞 + 𝐜𝐡𝐨𝐜 𝐭𝐚𝐬𝐭𝐢𝐧𝐠 (assuming this hasn't sold out immediately)

Starting to suspect my cat is some highly sophisticated being with two quantum states as he spends his days in the balcony, asleep on a chair, and regularly switching between pointing east or west *but I never see him move between the two*.

📣 We are seeking a postdoctoral research fellow in ancient metagenomics. Join us at the Institute of Genomics, University of Tartu. ⏳ 01.04.2026–31.03.2028 📚 1.0 position 📍 Riia 23b, Tartu, Estonia ℹ️ Project: lnkd.in/dQARuBxM ℹ️ Application: lnkd.in/dFR8DQxH ⏰ Deadline 02.02.2026

AI is the new GMO.

First cake of the year: lots of effort, looks beautiful, tastes of nothing. Sure hope it's not a metaphor.

Pinot Noir could not believe he was not invited to eat my dinner, especially because he hasn't been fed in approximately 13.4 years.

Impact of chronic underfunding 150 survey responses & counting. Please consider adding your voice and sharing your stories. lnkd.in/g8A_PAZG Storytelling is key to our humanity. We can make economic arguments and health arguments, but the power of stories can not be underestimated #SaveOzScience

Spent the whole day working on a paper draft and then destressed by making this beauty instead of looking at a screen:

I switched to Deezer so no Spotify wrapped for me, but I took my brother and mother to see Patrick Wolf two nights ago, and it was a lovely show - tiny venue, a crowd that knew and loved him. Kept thinking of how the first time I saw him play the summer of 2005, at the Islington Academy in London.

Have made it to Madrid after a lovely week at @sangerinstitute.bsky.social teaching on the new @eventswcs.bsky.social MAVE course. Amazing participants doing all kinds of cool high throughput science. When are we doing the next one?

Nearly sent someone an email about 'complex trait genetic infrastructure' instead of 'genetic architecture,' and I think I need a nap, friends.

this is unsustainable, the $600M underspend of the #MRFF could be funnelled, or at least partially funnelled, to supporting excellent #NHMRC applications that fall below the funding cut off because there is too little money in the pot #DiscoveriesNeedDollars #SaveOzScience

If you are planning to attend the Mutational Scanning Symposium (and companion workshops!) we recommend that you register as soon as possible to secure your spot! ℹ️ www.mss2026.org Keynotes! @mehurles.bsky.social @maitreya.bsky.social #VariantEffect26 #Symposium #Workshop #RegisterNow

Excited to share matchbox. It’s super fast and versatile to search for patterns in reads, I’m curious to see all the uses it will find! Congrats to @jakobschuster.bsky.social , co-supervisors @michaelbclark.bsky.social @mritchieau.bsky.social and team! www.biorxiv.org/content/10.1...

The Medical Research Future Fund (MRFF) funds medical research in Australia. Only half the funds have been released. If you're an Australian and able to vote please use the form below to email your local MP to release the full amount of the MRFF aamri.org.au/mrff/

Destroying the earth to make shit memes with GPT: (the idea was not mine, fortunately)

Ducks at Carlton Gardens this afternoon. Looks longitudinal but it's cross sectional 😅

Yeah :D

After two talks today, a well earned treat!

Mountains of Java; tea in Jakarta

Sitting in a hotel terrace in Jakarta and thinking about the (cultural? historical? accidental?) convergence in the flavours of the Colombian hot chocolate my first year RA made us in college, with cheese at the base, and pisang goreng served traditional style, with flecks of chocolate and cheese.

1/5 🦖 Michael Crichton’s Jurassic Park (1990) turns 35 in November. In a new preprint, I argue that it was a prescient meditation on evolutionary genetics, complexity, & control. I also examine analogous efforts of today (e.g. “de-extinction.") Select points below: ecoevorxiv.org/repository/v...

😍🤩😍🤩😍🤩

A hearty Denisovan stew ripe with stories of mixing and more mixing, even with a third more ‘archaic’ hominid. www.biorxiv.org/content/10.1...

In a new paper led by Jiaqi Yang we trace the distribution of Denisovan introgressed DNA in ancient modern human genomes over time. www.cell.com/current-biol...

Carole was my first boss, and working in her lab an an undergraduate was a fantastic opportunity. So great to see her get this award!!

New, from @navya-shukla.bsky.social and me: You have a new genome and want to test it for acceleration against other genomes: Tired: add it to an existing WGA with much toil and tears Wired: use our new approach to only add conserved regions! 🧬🧪🖥️

It's a shameful situation but at least the memes are entertaining

@jrossibarra.bsky.social maybe this is relevant to your interests?

Be sure to check out our monthly Seminar Series! 🔹Upcoming speakers www.varianteffect.org/seminar-seri... 🔹Previous speakers www.varianteffect.org/previous-sem... #Seminar #Series #Science #FunctionalGenomics

Ikea sending me this portable induction burner as an apology when my stovetop repairs took too long has brought me so much delicious joy.

Lol the Nobels can't even acknowledge women's contribution to discovery. But sure let's acknowledge The Machines.