Roughly half of common disease heritability is pleiotropic across diseases, with shared variance 1.51x enriched in the genetic component. Work led by Yujie Zhao (co-supervised by Alkes and me) is now out in @natgenet.nature.com www.nature.com/articles/s41...

Happy to share new manuscript I completed with @ee-reh-neh.bsky.social & @davisjmcc.bsky.social back in Melbourne. The work originally conceived by @ijbeasley.bsky.social focuses on how we can reconcile and meta-analyse eQTL studies across studies cohorts and ancestries. doi.org/10.64898/202...

Finally, today's offering! www.biorxiv.org/content/10.6... This began life as a very different project which failed because we couldn't agree on defining eqtl sharing across cohorts. So two young members of the lab dug deeply into this - first @ijbeasley.bsky.social, then @patrickgibbs.bsky.social

Power is a major confounder in the analysis of cross-ancestry 'portability' in human eQTLs https://www.biorxiv.org/content/10.64898/2026.02.26.708346v1

Hi yes I will have more to say about this in a few hours but please enjoy this paper. It's been a huge labour of love and effort for the last four years, and a significant part of our research efforts, and I'm so so so thrilled it's finally ready to share. Tldr: scRNA-seq in Indonesia hard but fun

Excited to launch our AlphaGenome API goo.gle/3ZPUeFX along with the preprint goo.gle/45AkUyc describing and evaluating our latest DNA sequence model powering the API. Looking forward to seeing how scientists use it! @googledeepmind

I cannot recommend Davis’s group more highly! In addition to excellent research, he has been a great mentor!

📢 PostDoc opportunity in our Bioinformatics & Cellular Genomics lab at SVI! 🧬 You’d join a welcoming, supportive, and brilliant team. Why not spend a few years in Melbourne and be part of something exciting? Apply here: www.seek.com.au/job/84737876 #ScienceCareers #PostDoc #Bioinformatics

Very happy to share that I will soon start a PhD at Cambridge University funded by the Harding Distinguished Scholar Fellowship, supervised by @mikeinouye.bsky.social and Angela Wood. I’ll work on prediction methodologies for health trajectories, using molecular data, and Electronic Health Records.

The FT reports OpenAI suspects DeepSeek of "a potential breach of intellectual property." As a columnist for NYT, which is suing OpenAI for copyright infringement, and the author of nine books OpenAI apparently used to train its model, I couldn't possibly comment. www.ft.com/content/a0df...

Very happy to share my first paper! Here we take a look at different models for producing genomic prediction across a wide range of traits. We find that very specific conditions of where ML approaches can out preform linear regression.

Earlier this year, I was nominated and funded by unimelb to attend the Heidelberg Laureate forum in Germany. The conference connects 200 developing researchers from maths and compsci to award winning scientists inc. winners of the Fields Medal and Turing award. It was an absolute blast!

Over 30 prominent scientists call for a ban on the creation of a "mirror cell"--a microbe made of molecules that are mirror images of their natural forms. It could cause a mind-boggling global disaster. Here's my story [gift link] 🧪https://nyti.ms/3OUCXp6