LISTEN UP, DORKS! @standupforscience.bsky.social is getting (even more!) political. People often say "well what can one person do??" 🥊 If all our followers joined Science Fight Club and gave $5 a month, we could save science! 🥊Join here: www.standupforscience.net/join-science... SHARE WIDELY!

Thank you Alzforum for featuring our new preprint identifying regulators of disease states of #microglia. Project led by Amanda McQuade, computation by Reet Mishra, collaboration with the Nunez and De Jager labs. Alzforum www.alzforum.org/news/researc... Preprint www.biorxiv.org/content/10.1...

On Sept 17th, 2025, @aaas.org and @researchamerica.bsky.social hosted Jay Bhattacharya—NIH Director—as the keynote for the National Health Research Forum. Less than two weeks later, he spoke at the MAHA Action hour alongside Oz, Russel Brand, Tony Lyons, and Callie Means. I have a call to action:

🎀 New from the lab 🎀 We used the SPARK design for kinase biosensors to develop a PINK1 biosensor, PINK1-SPARK. We used PINK1-SPARK to measure PINK1 activity in multiple cell types & when using HaloTag, for multiplexing! Plasmids coming soon, check out the preprint: www.biorxiv.org/content/10.1...

L.A. No Kings March: next Sat. (10/18) at 2pm in DLTA! L.A. Sign-making Party For No Kings: the night before! In West Adams! RSVP link below! @50501-socal.bsky.social www.mobilize.us/50501socal/e...

Researchers at UCLA built mini models of human lungs, hearts and brains to study hantaviruses and identify potential therapies. With no current treatments, these deadly rodent-borne viruses pose a serious threat to public health. #ResearchPowersProgress stemcell.ucla.edu/news/ucla-sc...

Los Angeles rents are high, especially compared to the average pay - but it wasn't always that way. In this video, LA Councilmember Nithya Raman goes over the history of why LA stopped building enough housing relative to the number of new jobs, and how the city can reverse that trend. 🏠🏠🏠

Excited that the paper presenting our mouse brain in vivo CRISPR screening platform is out today in @natneuro.nature.com! Great team effort, led by Biswa Ramani and @ivlrose.bsky.social in the Kampmann lab. www.nature.com/articles/s41...

2 bits of data from new Economist/YouGov poll..... 13% support for cutting research funding to universities. 24% among Republicans. Polling on this continues to be catastrophic for the Rs, suggests Dems should be learning far harder into standing up for science and our universities. 1/

“Los Angeles leaders are once again demonstrating their cowardice and failing their own constituents who desperately need more housing—and they’re doing it at the behest of LA’s wealthiest, most entitled voters, who have consistently blocked progress on housing affordability.” - @hanlon.bsky.social

In a first-of-its-kind clinical trial, UCLA scientists have shown it’s possible to reprogram a patient’s own stem cells to create a continuous supply of functional T cells, the immune system’s most powerful cancer-killing agents. bit.ly/4fhvMnv #CancerResearch #StemCellResearch

I'm thrilled to announce my next career step-- I’m joining Genentech as a Principal Scientist & Lab Head in Discovery Oncology! I’ll be hunting new ways to target cancers using my background in disordered nuclear proteins.

the republican party is a modern day Slave Power and the only way forward for this country is to sweep it into the ash heap of history

UCLA-led team has received a $3.5 million grant from the NIH to study and develop treatments for the infectious disease #mpox. Their discoveries could help prevent the next global outbreak. ➡️ bit.ly/3TW38hI

Logging off for the weekend, but shouting it one more time before I do: they don't believe in America. actioncookbook.substack.com/p/america-be...

Once again, this is a massive public jobs program for fascists. This bill was never just about tax cuts and gutting social services. It's about investing our collective resources in violence and using state power to spread fear and destroy solidarity. We need to resist this with all we've got.

I am grieving the barbarism that is going to unfurl from all this. People are going to die. Livelihoods gone. All to feed a corrupt kleptocracy. I see every day up close how different it is from the first time around. There are no guardrails. A disaster. I’m sorry we have to live through this.

Legitimately feel sick. We are hours away from the largest cuts to low-income people in history. People’s lives will be ruined. It is so unfair. It’s unfair to be born into a system that allows this level of poverty in the first place and it’s evil to rip away aid from the needy. Hard to watch this.

genuinely, kicking 17 MILLION people off of their health insurance and stripping TWO MILLON people off of food assistance is so grotesque and depressing it’s hard to think of anything else

GOP reconciliation bill's effects: —Poorest 1/5 of earners: *declining* after-tax incomes —Those making >$3 m/year gain $118,000 —12 m people become uninsured —3.2 m people lose food stamps —US stops its efforts to combat climate change —$122 billion spent on deportation & concentration camps

Our paper demonstrating that within-species warfare interactions are ecologically important on human skin is now published in Nature Micro! www.nature.com/articles/s41...

Basically the @elife.bsky.social model?

Final Senate votes in next 36 hours. www.mobilize.us/mobilize/eve... Save Medicaid NOW - Final Push Phonebanks to Republican Congressmembers · Mobilize

New preprint with Benjamin Lang, Richard Kriwacki, John Christodoulou, and M. Madan Babu! www.biorxiv.org/content/10.1... Protein Dynamics at Different Timescales Unlock Access to Hidden Post-Translational Modification Sites #bioinformatics #compchem #folding #proteindynamics

Elites aren't even using their existing mechanisms set up to allow deniable messaging. Go look at PhRMA, the big bad lobbying group; they've got nothing to say about their NIH R&D pipeline being destroyed, nor about the worst regression in public health and vaccine acceptance in U.S. history.

We're so close to fixing key drivers of California's housing crisis: ✅️ SB 79 would legalize apartments near transit. ✅️ AB 130 would end frivolous litigation against infill. ✅️ AB 253 + AB 1308 would prevent permitting/inspection delays. ➡️ Here's how you can help.

For Alzheimer's & Brain Awareness Month, we highlight the work of Dr. Jessica Rexach, a UCLA neurologist and neurogeneticist working to uncover the molecular drivers of Alzheimer’s disease. Learn more about her work: stemcell.ucla.edu/member-direc... #StemCellResearch #Neuroscience #BrainHealth

A big thanks to NC Rep. Valerie Foushee for being the first signature on this bipartisan letter urging the House to maintain a strong commitment to funding for NIH in the 2026 Appropriations bill. Is your Representative here? www.aamc.org/research/adh...

Check out Laura's thread on our latest preprint demonstrating best methods for low biomass skin sampling.

Interested in supporting the brave NIHers mentioned in RFK jr.’s hearing today? Join 29k of us - Nobel Laureates, NIHers, doctors, scientists & concerned citizens- in signing our letter of support: act.standupforscience.net/forms/add-na... #StandUpForScience #BethesdaDeclaration #SaveNIH #RFKjr

🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma 💥Now on @biorxivpreprint : biorxiv.org/content/10.1... Led by Dr. Shivani Baisiwala, Neurosurgery Resident in the lab

the biggest crew of goddamned idiots you ever saw

Big lawsuit filed today defending NSF. It’s a coalition including @aaup.bsky.social , @uaw.org , and @democracyforward.org . See thread🧪

Very much into this idea

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I listened to the hearing this morning in the two cases (now linked) about NIH grant terminations. These cases are before Judge William Young, a very accomplished judge appointed by Ronald Reagan. en.wikipedia.org/wiki/William... 1/n

Episode 4 of The Tortured Proteins Department is out now! We chatted about We chatted about the latest news, our Conformational Ensembles Conference, vibe coding in science, and recent running races. @fraserlab.com podcasts.apple.com/us/podcast/t... open.spotify.com/episode/2SLV...

Active duty military to the streets of an American city A military parade to celebrate the President’s birthday An emerging police state with secret police who cover their faces & disappear U.S. residents *Our democracy is in a red zone. We must mobilize to stop this.

This clip has me thinking about people finally taking Trump's ownership of the narrative, enforced by the massive GOP media advantage, seriously. Fox et al want people to believe LA is burning, terrible, overrun. LA has a lot of people who are pretty good at communicating, who can show otherwise!

Stand up for science - stand up for the NIH! I just signed the support letter for the #BethesdaDeclaration. Please consider signing as well: www.standupforscience.net/bethesda-dec...

If you live in California, call your state senator and tell them to oppose Monique Limon as senate pro tem because she’s a hardcore NIMBY who opposes rail electrification. They should support Lena Gonzalez instead, she’s the progressive pro-housing choice

I urge others to similarly support our patriots at NIH who use their training and talents to improve human health and position the US as the world’s leader in biomedical discovery, innovation and technology development 🙏

"Everything points to an effort to effectively destroy U.S. science — not gradually as part of a long-term plan, but over the next year or two." paulkrugman.substack.com/p/nobody-exp...

Seriously, help us control the narrative. Let every normie you know know: LA is chill, peaceful and safe right now. The protests are peaceful and there is no imminent threat to anyone. Even LAPD agrees.

Literally begging you to tell your friends, your neighbors, your coworkers, your family. People have vaguely heard of “the one big beautiful bill,” but very few people know Rs are WEEKS away from uninsuring millions - and will do it unless we can get a groundswell of opposition to stop them.

Can’t wait for Emily to start at UCLA!

It's impossible to make sense of American zoning, historically or today, without understanding that it has almost nothing to do with separating residential and classic nuisance. It's a mechanism of segregation, that's it.

It's do or die for SB 79, the bill that would legalize multifamily housing around rail and BRT stops across the state. The vote could be held as early as tomorrow morning. Californians: call your state senator tomorrow morning to help us get out of the senate! cayimby.org/legislation/...

“If things continue as they are, American science is ruined.” This isn’t sabotage from the outside — it’s self-inflicted. Cuts to research, visa bans, and closed doors to global talent are doing what an enemy of the US could only dream of. www.nytimes.com/2025/05/31/w...

Cutting $20 billion to NIH over 25 years may save $500 billion on paper, but it’d end up costing $8.2 trillion in lost human health. But NIH isn't the only thing being cut. The budget also slashes all NSF-funded science by 73 percent. NASA faces “the biggest single-year cut to NASA in history."