One of the things I’ll miss the most about NC - the local live bands I’ve come to know and love 😔

Hooding ceremony today followed by bluegrass & nc farm!

In this interview with @jpflores.rbind.io, recorded just one month after the 2024 elections, Sheeva talks about how her experiences in science have shaped how she sees science improving to better serve everyone. open.spotify.com/episode/0nqh...

Watching a cone snail harpoon a fish will absolutely blow your mind 🧠 For jp flores (he/him), it also starts to unravel something else: the pressure of always being “the smart one.” 🎧https://ow.ly/OlzV50YTbg0 #ScienceStories #TrueStories #Identity

Congratulations to Akshaya Vadivel, our amazing undergraduate, who received the 2026 AGA-Aman Armaan Ahmed Family SURF for Success Program Fellowship from the American Gastroenterological Association!!!! We are so excited for her continued excellence in the lab www.eurekalert.org/news-release...

We are hiring! Our research tech is starting her PhD in a few months. Come join us in our pursuit of discovery, surrounded by amazing colleagues in the @glialsciences.bsky.social at CWRU. Cleveland is super dope too www.scavuzzolab.org Please share widely: employment.case.edu/psp/ERECRUIT...

The armor works. Until it doesn’t. 🛡️ jp flores (he/him) shares a story about what happens when being “the smart one” stops protecting you—and starts pushing you toward something new. 🎧Hear his story on the podcast this week! https://ow.ly/Q1R250YTcRR #ScienceStories #RepresentationMatters #SciComm

(1/n) Super excited to share that our preprint is out today in @natsmb.nature.com with a new name "Integrated MINFLUX tracking reveals two distinct chromatin dynamics classes across cell types" and more than 2x more data: www.nature.com/articles/s41... See also MIT News news.mit.edu/2026/how-chr...

Got the grant 🥳

Also receiving a NAS award was Ilya Sutskever, cofounder of OpenAI whose new company Safe Superintelligence (currently just a webpage) is valued at $32 billion. The current budget of NSF is $9 billion; Trump wants to cut to $4 billion. Make this math make sense. >>

Great thread from an @nationalacademies.org award winner highlighting the current cowardice and capitulation of NAS, tech industry and the leaders of both to the demands of Trump that are destroying American science 🧪

Super excited to launch POCAxOMAP with @dschweppe.bsky.social and @oligopain.bsky.social and led by Eli Biletch, Conor Herlihy and Lidan Li. If you’ve ever wanted to do proximity labeling on DNA, RNA, or protein without genetic engineering, look no further. www.biorxiv.org/content/10.6...

Heidelberg - Düsseldorf - Amsterdam And ofc, lots of beer. PhD honeymoon!

Today in @nature.com, the @genophoria.bsky.social and & Vijay Ramani labs reveal that our picture of how nucleosomes regulate DNA accessibility has been too simple. They find that over 85% of nucleosomes in mammalian cells are structurally distorted, with DNA partially accessible even while wrapped.

roxygen2 8.0.0 out now: opensource.posit.co/blog/2026-05... ! So many goodies in this release including S7 support, tons of R6 improvement, a new config style, fewer dependencies, and so so many bug fixes #rstats

Sometimes the things we use to protect ourselves end up revealing the most. In tomorrow's episode, Christopher Moncayo-Torres and jp flores (he/him) build their own kind of armor and come face-to-face with what happens when it starts to crack. 🎧 OUT TOMORROW! #ScienceStories

It’s official! See you soon?!? @michelegabriele.bsky.social

🚀 We’re excited to share the release of Bioconductor 3.23, featuring: ✅2418 software packages (94 new) ✅437 experiment data packages (5 new) ✅928 annotation packages ✅8 books (2 new) ✅28 workflows 🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_...

Anyone have recommendations for things to do in Heidelberg, Düsseldorf, and Amsterdam?

Bioconductor 3.23 is released! Thanks to the core team for all the hard work that goes into a release, and to the package reviewers. The lab has a bunch of updates in here that I'll post in 🧵 over the next few days:

Pumped to see this out! Thanks so much to Erin, Misha, and the other wonderful folks @storycollider.bsky.social !

LMAO I made the same argument about the next generation of scientific mentors bsky.app/profile/need...

and that the next generation of political leaders needs to have the range and competencies to support a multi-racial coalition without undermining group cohesion and decision-making

Well this didn’t make me spiral or anything lol

Our H1 paper is out #ScienceAdvances: www.science.org/doi/10.1126/... @masaashimazoe.bsky.social et al. reveal that linker histone H1 acts as a liquid-like glue to organize chromatin in live cells. 🎉 Fantastic collab with @rcollepardo.bsky.social @janhuemar.bsky.social and others—huge thanks! 🙌 1/

📖 The final version of our paper is out in press Cohesin cofactor dosage sets the rate of loop extrusion, rendering genome folding tunable yet vulnerable to genetic disruption authors.elsevier.com/a/1m%7EU03vV... or www.cell.com/molecular-ce...

Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.

How do SMC complexes load onto DNA to get ready for loop extrusion? @roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️. Check out the new paper: www.cell.com/molecular-ce...

I am excited beyond description to lift the veil on what we have been working on in 2026: Please meet ggsql! A new extension of the SQL language for creating visualisations using the grammar of graphics. Read all about it in the blog post or visit the website at ggsql.org

Just saw this piece by @jpflores.rbind.io on a brief trip to X. It’s 100% spot on, and why I devote a lot of time speaking to classes and workshops for U-M grad students, residents & health services research fellows & faculty. (On top of writing/media relations) sciencepolitics.org/2026/03/18/w...

“Scientists are trained for a world where data speaks for itself. Where misinformation moves slowly. Where scientific expertise naturally rises above noise. That world is gone.”🧪 @jpflores.rbind.io

Excellent piece by @snapcoalition.org member Amanda Finn explaining the toll and harm of anti-DEI policies in #academia, particularly on #ECRs and people of color. #science #equity #DEI #gradstudents #PhD medium.com/science-poli...

Harvey Yang and I were fortunate to contribute polymer simulations to this paper from @nicholas-aboreden.bsky.social Zhao... Zhang, Blobel showing that most CRE loops can form de novo after mitosis without loop extrusion www.nature.com/articles/s41...

This @anshulkundaje.bsky.social, Kyle Fahr and William Greenleaf paper is finally out, we've been following it for a while in its preprint form, phenomenal work. www.nature.com/articles/s41...

DNA is not the same as kinship. Our perspective paper argues that treating genetics as the ultimate proof of identity or family can: • erase community-defined relationships • reinforce Western biases • and even cause real harm in policy + research Special Issue: www.cambridge.org/core/journal...

@snapcoalition.org runs 10-milers too!

Told myself to do it even though I def didn’t train and v surprised! This place is called chapel HILL for a reason

This program transformed my career! Please apply. @hhmi-science.bsky.social's #FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits. Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA

ALSO TODAY: Misha Angrist attends a science conference during what has been opaquely termed "turbulent" times. "The other thing that struck me was the strange business-as-usual, whistling-past-the-graveyard vibe running through the conference." flaminghydra.com/scholars-ret...

See also the concordant and related papers from @tessapopay.bsky.social @jesserdixon.bsky.social www.nature.com/articles/s41... UkJin Lee @efapostolou29.bsky.social www.nature.com/articles/s41... @karissalhansen.bsky.social @elphegenoralab.bsky.social www.science.org/doi/epdf/10....

New paper in Genes & Dev: we dissected how Sox2 — a key pluripotency TF — is regulated by a distal enhancer cluster (SCR) 100 kb away. The results challenge simple models of cohesin-mediated loop extrusion of gene regulation. genesdev.cshlp.org/content/earl... 🧵

Join us in October for a conference focused on the full functional diversity of the peripheral nervous system, highlighting how somatic/autonomic/enteric divisions interact, overlap & inform one another. Apply by May 14 ➡️ janelia.news/PNS26 @ardemp.bskyverified.social @marissascavuzzo.bsky.social

Excited to read this! @andersshansen.bsky.social @nicholas-aboreden.bsky.social www.nature.com/articles/s41...

We are thrilled to announce that Positron Server is now available for academic use via JupyterHub! This gives students a robust #RStats & #Python data science IDE without needing a local install or new infrastructure. Learn more: positron.posit.co/blog/posts/2...

A star scientist showed that better genetics lessons could reduce racism. It was the death knell for his career. Thank you, @mmolteni.bsky.social for sharing Brian's story. He is a generational talent, indeed, and has inspired my own educational activities deeply. www.statnews.com/2026/04/07/b...

30 seconds of life as a #GilliamFellow, thanks to the 19 cohort members who attended our March Science Meeting alongside ~70 additional HHMI scientists. Potential applicant? Imagine yourself here, and mark Sept. 1 on your calendar to apply!

Some science cuts in Trump's proposed FY27 budget ❌ NIH: -$5B, including all of NIEHS, NIMHD, FIC & NCCIH. ❌ EPA: -4.6B ❌ NSF: -3.8B ❌ NASA Science: -3.4 Billion ❌ NOAA: -1.8B, including the entire Oceanic and Atmospheric Research budget ($605M) ❌ AHRQ: All of it. -$296M, 100% And there's more.