#NIHFundedDiscovery How do cells avoid the "kiss of death"? Gap junctions share life-saving signals—but under stress, they shut down to prevent spreading cytotoxic damage. #CryoEM reveals the molecular switches behind this process! www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...

Super excited for this one! High-res #cryo-EM ensemble of sHSP/client complexes, uncovering 'Mechanism of small heat shock protein client sequestration and induced polydispersity' www.biorxiv.org/content/10.1... A teaser...👇

Pleased to share the peer-reviewed version of our latest work on resolving the complexities of a-crystallins/sHSP's: www.nature.com/articles/s41... A timely release of this story... as it is a great setup to the next one, coming soon!!

Inaugural post sharing a newly updated version of our little protocol for high quality fiducial removal in #CryoET processing