Delighted to see our paper featured on the cover of JNeurosci. this week. While this study focused on the role of SCD1 in developmental myelination, the data also pointed us toward potentially broader functions for SCD2 that we are now actively pursuing #sfnjournals www.jneurosci.org/content/46/1...

The Duncan lab is hiring a postdoctoral fellow! We study how neurons respond to and are injured by demyelination. We use snRNAseq, microscopy, electrophysiology and molecular biology approaches. If interested, please send a statement of interest and CV. www.neuroscience.umn.edu/faculty/curr...

Latest offering. How myelin ensheathes axons! Born from chat with Dwight Bergles on "weird things" we saw oligodendrocytes do, like making "bridges" between sheaths. Driven forward by Cody Call, Kelly Monk, and myelin folks @edinburgh-uni.bsky.social Enjoy! www.nature.com/articles/s41...

Megan Doty et al discovered that myelin remains for weeks after cortical axons degenerate. We call the sheaths without an axon de-axoned myelin. During the slow, asynchronous, degeneration, microglia don't play a major role in clearing the axon or de-axoned myelin. www.science.org/doi/10.1126/...

How does inflammation kill neurons, and what can we do about it? Check out our latest paper where we consider this question: rdcu.be/e4nfP.

Myelin is repaired by constitutive differentiation of oligodendrocyte progenitors www.science.org/doi/10.1126/...

We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth. Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...

Rodriguez Salazar, @caglaeroglu.bsky.social et al. show that Drp1-mediated mitochondrial fission is necessary for peripheral #astrocyte process formation. rupress.org/jcb/article/... 📕 Part of The Year In Cell Biology: rupress.org/jcb/collecti... #CellBio2025 #Mitochondria

Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1

Our work out in @devbiol.bsky.social, PDGFra is needed for 🧠 perivascular fibroblast development... ⬇️ perivascular fibroblast = ⬇️ perivascular macrophage...cross-talk? 👀 Led by Hannah Jones @hejcell.bsky.social w/ Kelsey Abrams, Sophia Kim, excited for more projects w/ @fantauzzolab.bsky.social!

Check out our recent preprint, "Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish." lnkd.in/gN7z6th4

Obituary: Jose Manuel García-Verdugo (1954–2025), an Exceptional Eye Into the Fine Structure of the Brain's Germinal Centers Arantxa Cebrian-Silla, Mercedes Paredes, Arturo Alvarez-Buylla onlinelibrary.wiley.com/doi/10.1002/...

Our postdoc ad is up on the SDB website! Come to Portland and study regenerative neurogenesis in planarians and zebrafish: www.sdbonline.org/resource?Res...

Nature research paper: Axonal injury is a targetable driver of glioblastoma progression go.nature.com/4lFmpiN

Another beautiful study by the lab of @andyshihlab.bsky.social published today in @natureportfolio.nature.com 👏🏻👏🏻👏🏻 #cerebrovascular #aging

Fantastic new study on the role of TMEM63a in oligodendrocyte-dependent myelination in the CNS from the Swetha Murthy lab: pubmed.ncbi.nlm.nih.gov/40694323/

#Cerebrovascular #Neurovascular

Directional growth of developing myelin mediated by Wnt gradient and required for proper axon functions https://www.biorxiv.org/content/10.1101/2025.06.13.659097v1

For those who want a distraction and/ or are interested, here's the latest from the group, led by Phil Braaker www.nature.com/articles/s41...

New paper out from the lab! Led by @gdfnunes.bsky.social and Lindsay Osso in collaboration with the lab of Dan Denman. Check it out! 🔬 🐭 🧠 www.nature.com/articles/s41...

Genetically Labeled Premyelinating Oligodendrocytes: Bridging Oligodendrogenesis and Neuronal Activity https://www.biorxiv.org/content/10.1101/2024.12.27.630559v1