Here's a movie from the 3D neuroimaging paper - this is the telencephalon of a 19 month old tg(kdrl:mCherry, mpeg1:eGFP) fish. We use imaris to strip the top layer (the skin and skull) off the projection so we can see just the tissue beneath the skull. This was taken with a Bruker 2P+ multiphoton.

Want to image the adult zebrafish brain? Here's a nifty design that I made with the help of a talented master's student, Corey Steinhauser. Supporting files here! morgridge.org/research/lab...

My pre-print from the Shikanov Lab is live! We detail oocyte and somatic transcriptome, and whole follicle proteome signatures driving folliculogenesis in vitro towards improved ART. www.biorxiv.org/content/10.1...

Very excited and proud to share my postdoctoral research with @neurrriot.bsky.social looking at the context-specific encoding of social behavior 💃🕺 in hormone-sensitive, large-scale brain networks in mice! www.biorxiv.org/content/10.1... #neuroskyence #compneurosky 🧪 1/12

Feeling grateful for everyone who supported me during my PhD and post-doc training: my incredible mentors David Julius and Vanessa Ruta, my wonderful lab mates, and the amazing communities @leadingedgeprogram.bsky.social @ucsfhealth.bsky.social @rockefelleruniv.bsky.social and HHWF

I'm excited to share that I've started my lab @stanford.edu in the Neurobiology Department! neurobiology.stanford.edu/who-we-are/f... #stanford #newPI #neuroscience

Excited to announce the opening of the @fitzsimmonslab.bsky.social at @michiganstateu.bsky.social dept. of biochemistry & molecular biology! (1/3)

@accorsi-alice.bsky.social studies how freshwater apple snails regrow their eyes—with the goal of helping to restore vision in people with eye injuries. Her team developed methods for editing the snail’s genome, allowing them to explore the genetic and molecular mechanisms behind eye regeneration.

I’m honored to serve on @dystoniafoundation.bsky.social ‘s medial and scientific advisory board for the next four years. news.vt.edu/articles/202...

Excited to share our new preprint co-led by @jnoms.bsky.social! Here we reveal an exceptional diversity of viral 2H phosphodiesterases (PDEs) that enable immune evasion by selectively degrading oligonucleotide-based messengers. This 2H PDE fold has evolved striking substrate breath & specificity.

Excited to share our recent viewpoint with @storerlab.bsky.social led by Kirsten Sadler, on epigenetic mechanisms of regenerative resilience. Ageing versus developmental silencing: Answers from the epigenome - Sadler - The FEBS Journal - febs.onlinelibrary.wiley.com/doi/10.1111/...

Happy to get to contribute to this perspective in JEM!

This #MicroscopyMonday is a developing Apple Snail embryo. On the left is the shell, the middle the body & the foot at the bottom. On the right the head with the eye (green circle) & the tentacle bud. (@planaria1.bsky.social lab) #ResearchSky #SciSky

🐌👀What do apple snails have to do with human vision? Stowers scientists took a chance on a tiny creature, with big results. Learn how @planaria1.bsky.social & then postdoc @accorsi-alice.bsky.social brought apple snails to the Institute. ⬇️ #ResearchSky #SciSky Learn more: youtu.be/U-yQ7z1e6nA

This week we said farewell to the amazing @caitlinkowa.bsky.social as she moves to start her new lab at Dartmouth. So grateful for all her leadership and mentoring the last few years. If you’re interested in all things skin microbes (especially fungi) check out her lab! I can’t recommend enough.

Our paper has finally graduated from pre-print to peer-reviewed, pretty much unscathed, and is out now! www.cell.com/cell/fulltex...

I’m excited to share our new T cell aging study published in Nature Communications @natcomms.nature.com ! We show that T cells do not age uniformly but undergo distinct aging trajectories even if they were primed simultaneously early in life. www.nature.com/articles/s41... 👇👇

Which llms are best for coding help? what strategies help students actually learn how to write and eval code? I'll continue asking probing q's and emphasize checking work, but rn feel like i cant trust any of their plots...2/2

This summer I'm noticing students embracing vibe coding for data analysis to worrying effect. #Neuroskyence #🧪 1/2

Super excited to share my final postdoc paper from Rabinowitz lab- on how whole-body and tissue metabolism changes in viral infection! pubmed.ncbi.nlm.nih.gov/40581045/

My postdoc work on attention in the mouse whisker system is out now in @natcomms.nature.com! We show that mice flexibly allocate attention to recently rewarded touch stimuli on a trial-by-trial basis, with corresponding modulation of the S1 neural code (1/6).

Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.

Exciting news: ⭐I'm thrilled to receive a grant from the Brain Research Foundation! tinyurl.com/2p9ku4sd ⭐"Atypical retinal ganglion cell function in a mouse model of Fragile X syndrome" was published! tinyurl.com/htk3ekce ⭐my review on retinal receptive fields was published! tinyurl.com/48b9xbs2

A recent study from @shiraweingarten.bsky.social, a former postdoc in the Rice laboratory, revealed 4,208 previously unknown proteins that are made by viruses such as influenza and H.I.V. using a new technique called massively parallel ribosome profiling.

Congratulations @allynguyen.bsky.social !!!

Just out @pnas.org : our work on primate testis maturation during fetal development. www.pnas.org/doi/full/10....

So excited to announce our preprint describing a high-throughput method for mapping connectivity across neuron types! Using a combination of optogenetics, voltage imaging, and mFISH in over 1000 neurons, we describe new connectivity motifs in long-range inputs to the motor cortex.

Extremely excited to share I have accepted an offer to be an Assistant Professor in the MCDB department at the University of Michigan! Go Blue! The Ledvina lab will investigate the molecular interworking of the bacterial immune systems including defense against both viral and bacterial pathogens.

Congratulations @almudenachaves.bsky.social !!!

New paper from the lab officially out! Congratulations @marisosa.bsky.social - amazing work - and just before she sets off to UC Boulder to start her own lab!

Excited to present our lab’s work at #ISSCR2025 at Hong Kong! Looking forward to catching up with friends and making new ones. Catch me at the concurrent session on “Stem cell models of tissue injury and repair”.

Congratulations to postdocs Melissa Pamula and Amelie Raz, who have both been named 2025 Leading Edge Fellows! www.leadingedgesymposium.org/fellows @remlehmann.bsky.social @leadingedgeprogram.bsky.social

New preprint in the lab combining what we like best: insects, love, chemistry and the olfactory system! 1/8 www.biorxiv.org/content/10.1...

🧪 The final work from my PhD is finally out today! We found that synapses at the larval fruit fly neuromusculsr junction (NMJ) were individually highly diverse in their synaptic release properties. However... (1/5)

Not that it matters, but my MOSAIC was scored a 14. Reviewed in study section w non-MOSAIC K99s. I'm to write another grant that may not be funded, that doesn't provide transition to faculty funds, instead of doing the work that was reviewed so highly? That's the best use of time & tax payer money?

We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines. Learn more about these exceptional scientists: www.leadingedgesymposium.org/fellows

I am thrilled to share our preprint where we take advantage of the unique opportunities offered by human blastoids to uncover a human-specific mechanism potentially playing a role in preimplantation 🧵. www.biorxiv.org/content/10.1...

Hooray for @accorsi-alice.bsky.social !!!!!! 🐌🎉🧪

So great to see @xintong.bsky.social while visiting UT Dallas @leadingedgeprogram.bsky.social

Exciting news!! I’m joining the tenure-track faculty at University of Colorado Boulder this fall as an Assistant Professor of Psychology & Neuroscience! The Sosa Lab will study how memory is shaped by cognitive and physiological demands, including during pregnancy and the postpartum period. 🧵

Excited to share that our story on S. aureus antagonism by Malassezia is live today in Current Biology! The paper has changed a lot since the preprint with the very exciting addition of having identified the antimicrobial effector generated by M. sympodialis. authors.elsevier.com/c/1kwzj3QW8S...

Huge congrats to talented graduate student Fia Stratton on receiving the NSF GRFP today! So proud and excited to see all the incredible science you'll do — well deserved! @einsteincellbio.bsky.social @einsteinmededu.bsky.social

Excited our preprint is out looking at BZ resistance in wild #Celegans, C. briggsae, and C. tropicalis strains! #anthelmintics 🪱🎉

In my 25 years since high school I’ve seen 1. HIV/AIDS go from death sentence to manageable with drugs 2. Cystic fibrosis go from pretty much an extended death sentence to manageable with drugs 3. Sickle cell go from a horrible disease to (almost maybe) cured by gene therapy Simply incredible

I am excited to share our study showing how the immune system strikes a delicate balance between tolerating food and defending against helminth infections. www.science.org/doi/10.1126/....

Exciting news: Our very own @mariaperezmi.bsky.social has secured a highly competitive UCL Research Excellence Scholarship to do her PhD in our lab. Here comes another #first, the first PhD student of the Delas lab. Stay tuned for lots of fun science! 👩‍🔬🧫👩‍💻🔬🧪 Congratulations, Maria!

Great piece about our upcoming rally in the Sun-Times by @neilsteinberg.bsky.social Meet the organizers behind Chicago's Stand Up for Science Rally #standupforscience #scienceforall @standupforscience.bsky.social chicago.suntimes.com/columnists/2...

Each piece of good news no matter how small is like a knife of light and we will need many to cut through this shroud. There I no question we will need a concerted effort to help our colleagues who find themselves in a terrible situation through no fault of their own. But we can do both. /2

Glad to share this finally! We explored how modulating host factors could improve dual rAAV vector transduction. Key takeaways: HDR inhibition boosts expression & concatenation, and transient HDRi enables lower doses & higher efficiency! More to come in the Maurer Lab. www.nature.com/articles/s41...

This is an uncertain moment in science, but I'm committed to doing what I can to support the individuals in my lab and new community at NYU. We have important work to do. Stay tuned for updates. For now: we're hiring! Contact me about opportunities for postdocs and @nyugrossman grad students.