Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

Find our latest Perspective article in Nature Genetics on "The role of KRAB zinc-finger proteins in expanding the domestication potential of transposable elements" at www.nature.com/articles/s41..., with implications for the future of research on the cause of human disease.

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social doi.org/10.1016/j.ce... Read the thread👇 for the highlights of our findings.

We are hiring! Join the Jachowicz lab as a postdoctoral researcher. The project focuses on understanding the dynamics of ncRNAs using high-resolution and single-molecule microscopy approaches. Link below 👇

Our paper is now out in Nature: “Ancient co-option of LTR retrotransposons as yeast centromeres” www.nature.com/articles/s41... A short thread on how retrotransposons helped give rise to yeast point centromeres. 1/14

Looking forward to it!

Ever notice that when one gene is disrupted, its orthologs get upregulated? This phenomenon, known as transcriptional adaptation, has been controversial and mysterious - glad to see that we are starting to learn how it works.

New Year, New Paper!🎊 Pervasive cis-regulatory co-option of a transposable element family reinforces cell identity across the mouse immune system www.biorxiv.org/content/10.6... Centerpiece of Jason Chobirko's PhD, talented PhD student co-mentored by Andrew Grimson & me. Really excited about it!🧵

🚨New paper from our team on our favorite sex locus ANTSR! 🚨New collaboration with @hugodarras.bsky.social , led by our talented @chuanxinyu.bsky.social, we show that ants, bees and stinging wasps share an ancient sex locus, a suspicion we had when we first found the locus in the Argentine ants!

Happy to begin the year with the publication of a Journal Club article - Programmed ‘DNA splicing’ removes transposons from genes. rdcu.be/eXBym

Don't miss this great opportunity!

🧠Si eres Investigador/a Postdoctoral y quieres incorporarte a nuestro lab #Parkinson #Metabolism #Mitochondria - 5 años desde la lectura de tesis. - 1 año de estancia internacional. ⚠️Contrato postdoctoral de 3 años con estabilización. Contáctame: [email protected] 📍IBiS, Sevilla

Open Senior Bioinformatician position at @sangerinstitute.bsky.social Tree of Life, to work on the Biodiversity Cell Atlas initiative with @marakat.bsky.social and me. 📅 Apply by January 18 🔗 sanger.wd103.myworkdayjobs.com/en-US/Wellco... Please share with anyone who might be interested!

I’m so excited to share that I’ve accepted an assistant professor position at the University of Colorado Anschutz, BMG department and Barbara Davis Diabetes center! I’m so grateful to many who have helped me get here, especially mentors at Joslin, @hmsbpa.bsky.social @leadingedgeprogram.bsky.social

🚨 Postdoc opportunity! If you’re interested in applying for a postdoctoral contract in #Neuroscience, #BrainEnergyMetabolism & #ParkinsonsDisease, email me: [email protected] 🔗 lajunta.es/6697y

🧬 Are you interested in synthetic biology, CRISPR-Cas9 genome editing and cutting-edge genomics? Apply by 07.01.2026 to join Stefan Mundlos’ lab @stemundi.bsky.social at the MPIMG. #IMPRS-BAC #gradschool! @nataliabenetti.bsky.social 👉 www.molgen.mpg.de/5124667/Mund...

Very happy that this part of my postdoc work is now out as a preprint!! Our findings reveal a new mechanism by which retroviral pandemics may have shaped primate brain evolution 🧬🐒🧠 This was a true team effort! w/ @ofeliakarlsson.bsky.social @raquelgarza.bsky.social @jakobssonlab.bsky.social #TEsky

Excited to co-organize with @weieli.bsky.social a symposium at SMBE 2026 on how synthetic & systems biology can illuminate the molecular mechanisms of evolution. Honored to have @christianlandry.bsky.social as invited speaker! Join us!

We are excited to share our new preprint: SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids. www.biorxiv.org/content/10.64898/2025.12.01.691499v1

Tomorrow (Thursday) at the Systems Virology Journal Club, Noor Youssef will present her work with Debbie Marks on developing an AI model that predicts how viruses evolve to evade the immune response. Paper: pubmed.ncbi.nlm.nih.gov/40345199/

The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts. We have been mapping mRNA modifications for over a decade. => Characterizing their functions -- especially on translation -- is a research frontier.

The IMPRS-BAC is an outstanding PhD program in Europe. And the endogenous retroviruses in development... what can I say? So much exciting biology to uncover! 🦠🧬#TEsky #StemCells Read the instructions and apply! ⬇️⬇️⬇️

🔬 Hot #PhD topic: Single-molecule fluorescence and super-resolution microscopy! Use quantitative nanoscale imaging to map nuclear organization. Apply by Jan 7 to join Johannes Stein’s Lab @jmstein.bsky.social & #IMPRS-BAC #gradschool! 👉 www.molgen.mpg.de/5098010/stei...

🪱 Selfish genes are everywhere and drive some of biology’s biggest innovations (CRISPR, antibody recombination, epigenetics). Yet almost no one asks the obvious question: how does a selfish gene begin? Our new manuscript uncovers how selfishness can emerge directly from the host genome.

We are excited to participate this year again in the VBC summer school! If you want to work with me and my amazing student Maria, apply!

Registration is open for "The complex life of #RNA" 2026 @embl.org in Heidelberg! Excellent invited speakers and 30 short talks and even more flash talks selected from the abstracts!

It's always special when you find your own paper in the table of contents of the journal 😍 "The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube" -> Now out in its final form www.cell.com/developmenta...

IMPRS-BAC #gradschool: Our new groupleader @sedonamurphy.bsky.social has an open PhD project in her lab. Topic: Spatial feedback between epigenetic regulation and chromatin regulation. Apply by Jan 7, 2026! 👉 www.molgen.mpg.de/5091778/Murp...

Thrilled to share our new review in Current Opinion in Genetics & Development on TE driven innovation in gene regulation🤘. I am honored to be part of this with two major TE aficionados @cedricfeschotte.bsky.social and @trono-lab.bsky.social #TEsky #TEworldwide authors.elsevier.com/c/1m6MC,LqAZ...

📣 SAVE THE DATE Next X-inactivation meeting in Sapporo, Japan, 19-23 October 2026. Visit x-inactivation-meeting.org to join our mailing list. 🧬 speakers @dandergassen.bsky.social @marnieblewitt.bsky.social @heard65.bsky.social @crougeulle.bsky.social @sexchrlab.bsky.social @zhouqi1982.bsky.social

Happy to share our paper now out in @cp-cellreports.bsky.social - and check out our thread about the findings at bsky.app/profile/vale...

We have a new lab photo. Busy times in the Delas Lab! Last month Maria and Shaun joined us to start their PhDs. Learn more about our research and our team: delaslab.com We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.

70s Glam-Rock phenotype! I love this story! Congrats to all the team 🍾

So many memories and feelings cleaning up boxes... Where do the unfinished projects go? Are the amount of plastic tubes used worth the discoveries? Also, this picture could serve as my CV...

We're very excited to welcome Dr. @sumrubayin.bsky.social from the @gurdoninstitute.bsky.social onto the next episode of the podcast! 🎉 Her lab studies the mouse #cerebellum to better understand the regulation of #neural stem cell behavior. 🧠

📣 Paper alert! I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today! journals.biologists.com/dev/article/...

We recently reported that promoter competition can contribute to the robust insulation of gene regulatory domains (www.nature.com/articles/s41...). We now offer a 4-years PhD contract to investigate whether the dirsuption of this regulatory mechanism can lead to congenital defects. More details 👇

Thrilled to start my Group Leader adventure with these and other great scientists!

Having a lot of fun at #EMBOMobileGenome 😃 Perfect timing for our paper from the lab of @toddmacfarlan.bsky.social to be out @natcomms.nature.com!! …and I’m currently on the job market looking for a new scientific home! www.nature.com/articles/s41...

The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/

🥁This Wednesday , in #FragileNucleosome seminar, we are excited to host @hannahlong.bsky.social and @jeffvierstra.bsky.social to tell us about amazing work they are doing! 🗓️Register here for upcoming session and the entire series: us06web.zoom.us/webinar/regi...

Join us to hear about writing and re-writing the central dogma! Looking forward to hosting Samuel Sternberg @sternberglab.bsky.social from @columbiauniversity.bsky.social for our Dahlem Colloquium Seminar at the MPI for Molecular Genetics @molgen.mpg.de - see below 👇

1/ Excited to share our new study with @brumbaugh-lab.bsky.social, out in @natbiotech.nature.com! P-bodies selectively sequester RNAs encoding cell fate regulators, often from the preceding developmental stage. Releasing these RNAs can drive changes in cell identity. 🧵 www.nature.com/articles/s41...

Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!

Gracias a las empresas, medios de comunicacion y al @csic.es por ser parte del itinerario Ciceron de Conexion GENOMA: >170 grupos de investigación de todo el estado avanzando el conocimiento sobre la función, estructura y evolución del #genoma

Check out @jaguilarrod.bsky.social and @petrovadmitri.bsky.social thought provoking work! If like me, you feel this work may be out of your comfort zone, make sure to read Jose's bluetorial, clearly explained! Congratulations!

My lab is seeking two PhD candidates to investigate the function and regulation of endogenous retroviruses in the early stages of human development 🦠👩‍🔬. Apply through the International Max Planck Research School (IMPRS) program: www.molgen.mpg.de/IMPRS/applic.... www.molgen.mpg.de/5094682/Fuey...

Congratulations @katerinakraft.bsky.social, @sedonamurphy.bsky.social and @mattjones.bsky.social ! Very cool!

🎃We are ready & excited for the new #FragileNucleosome seminar session tomorrow with @alicelaigle.bsky.social and @seungsookim.bsky.social ! How about you ?