Pauline Franz
@paulinefranz.bsky.social
📤 1323
📥 757
📝 9
Chemical Biologist in 🇬🇧 ¦ passionate about illustrating science 🐡
#proteinchemistry
pinned post!
What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the
@angewandtechemie.bsky.social
Frontispiece!! ▶️
tinyurl.com/mvtecrsz
@beatfierz.bsky.social
#chemicalbiology
#clickchemistry
#DNArepair
#SciArt🐡
🧪
about 1 year ago
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Pauline Franz
Matteo Doudin
9 months ago
I am very happy to share that I was awarded a PhD fellowship from the Boehringer Ingelheim Fonds (BIF) for my project about nucleosome depletion in
@lcbm-epfl.bsky.social
with
@beatfierz.bsky.social
. Looking forward to joining the BIF community 😊🥳
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Pauline Franz
Carlos Moreno-Yruela
11 months ago
#SIRT7
is a histone deacetylase with highly specific activity on
#chromatin
substrates. We just published mechanism-based
#cryoEM
structures of
#SIRT7
on nucleosomes to understand its activity 👇
www.nature.com/articles/s41...
(1/8)
#ChemBio
#ChemSky
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Pauline Franz
Rob Schneider
about 1 year ago
Please RS/RT.
#GordonConference
on "Histone and DNA Modifications"
#epigenetics
#chromatin
20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now
www.grc.org/histone-and-...
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Pauline Franz
Tim Triche, Jr.🔰
about 1 year ago
Dear world: this is what a graphical abstract is supposed to look like.
add a skeleton here at some point
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What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the
@angewandtechemie.bsky.social
Frontispiece!! ▶️
tinyurl.com/mvtecrsz
@beatfierz.bsky.social
#chemicalbiology
#clickchemistry
#DNArepair
#SciArt🐡
🧪
about 1 year ago
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Pauline Franz
Angewandte Chemie
about 1 year ago
Hi there: we're happy to be on BlueSky now, too! Stay tuned as we're getting set up here for the
#ChemSky
community - more to follow soon!
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Pauline Franz
Nina Hartrampf
about 1 year ago
🥳 Today we celebrated the PhD defense of our very first PhD student Kevin Schiefelbein 🤩 Kevin told us about his Lasso Peptide journey over the past four years, and it was so great to see the full story coming together. Congratulations Kevin, and thank you for everything!
#proudPI
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Pauline Franz
Altmetric
about 1 year ago
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Pauline Franz
Life Sciences Switzerland (LS2)
about 1 year ago
We want to thank everyone for joining and to congratulate the winners! A big thank you to all sponsors supporting this meeting! We hope to see you all next time.
#LS2
#ICMT
#Biophysics
#LifeScience
#Switzerland
#Conference
#Science
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Pauline Franz
Micha Rapé Lab
about 1 year ago
Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI.
www.biorxiv.org/content/10.1...
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Pauline Franz
Micah G. Allen
about 1 year ago
Would you like to see
@biorxivpreprint.bsky.social
add a share to blue sky button?! I know I would! Share this post to let
@richardsever.bsky.social
@erictopol.bsky.social
and others at bioarxiv know!
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Pauline Franz
Alexis Verger 🧬🧫🧪
about 1 year ago
Look who's here
@pnas.org
✔️
@science.org
✔️
@naturecellbiology.bsky.social
✔️
@natrevgenet.bsky.social
✔️
@naturebiotech.bsky.social
✔️
@naturemicrobiol.bsky.social
✔️
@naturechemistry.bsky.social
✔️
@genesdev.bsky.social
✔️
@cellchembiol.bsky.social
✔️
@genomeresearch.bsky.social
✔️
@jcellbiol.bsky.social
✔️
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Pauline Franz
Simon Rössler
about 1 year ago
MIT researchers in collaboration with Novo Nordisk report in Nature an alternative to injections for the delivery of biologic drugs. This needle-free method leverages an ingestible capsule inspired by squids that releases drugs directly into the digestive tract wall.
www.nature.com/articles/s41...
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Cephalopod-inspired jetting devices for gastrointestinal drug delivery - Nature
Tethered or ingestible delivery systems that deliver liquid microjets in axial and radial directions can be used to deliver macromolecules to different parts of the gastrointestinal tract with good bi...
https://www.nature.com/articles/s41586-024-08202-5
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Pauline Franz
Waser Group
about 1 year ago
On November 20, the new class of peptide-cyanobenzene dye photocatalysts developed by Xingyu have been first made public in a preprint at ChemRxiv, including a great collaboration Wei Cai in the
@beatfierz.bsky.social
group and Dr. Anne Sophie Chauvin
chemrxiv.org/engage/chemr...
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Pauline Franz
Spirochrome
about 1 year ago
Celebrating
#FluorescenceFriday
and hopefully brightening your timeline with these live intestinal
#organoids
stained with our actin probe SPY555-FastAct.
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Pauline Franz
Rita Strack
about 1 year ago
This the (short, funny, sad) video we got to see on imaging women's brains at the CZI Imaging meeting as part of Nina Miolane's talk. Worth a few minutes and worth a share.
www.youtube.com/watch?v=tX5u...
add a skeleton here at some point
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Pauline Franz
Alexis Rohou
about 1 year ago
🚨 Attention
#teamtomo
PhD students! 🚨 12-week paid internship opportunity at Genentech. Want to see how we use cryoET in pharma? And spend the summer 2025 in the Bay Area? Details and application link here:
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
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2025 Summer Intern - Department of Structural Biology
Department Summary The CryoEM Group in the Department of Structural Biology is dedicated to providing high-resolution structural insights into biological macromolecules involved in health and disease....
https://roche.wd3.myworkdayjobs.com/ROG-A2O-GENE/job/South-San-Francisco/XMLNAME-2025-Summer-Intern---Department-of-Structural-Biology_202411-129173
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Pauline Franz
Altmetric
about 1 year ago
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky
#HigherEd
#Altmetrics
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Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
https://docs.bsky.app/docs/advanced-guides/intent-links
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Pauline Franz
Thorn-Seshold Lab
about 1 year ago
📯📯 Chemical Biology starter pack 📯📯 140 PIs & groups posting primary research in chemical biology. Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem
#FluorescenceFriday
#chemsky
#chemtwitter
#AgentOrange
add a skeleton here at some point
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Pauline Franz
Razvan Borza
about 1 year ago
⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️ 🔄Share to help people finding its topic/field - STRUCTURAL BIOLOGY Structural Biology 1:
bsky.app/starter-pack...
Structural Biology 2:
bsky.app/starter-pack...
Crystallography:
bsky.app/starter-pack...
Synchrotron&CryoEM:
bsky.app/starter-pack...
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Pauline Franz
Rune Busk Damgaard
about 1 year ago
Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️
go.bsky.app/3VPQofn
add a skeleton here at some point
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Pauline Franz
Dorien Pastoors
about 1 year ago
I am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack
go.bsky.app/Jq8YaQM
- if you would like to be removed/added please let me know
add a skeleton here at some point
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Pauline Franz
Chemistry World
about 1 year ago
More than 9000 studies published in open-access journals contain figures created using the commercial scientific illustration service BioRender, which should technically mean that they are available for free reuse. But that doesn’t appear to be the case.
www.chemistryworld.com/news/thousan...
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Thousands of published studies may contain images with incorrect copyright licences
Questions raised over copyright licence that covers images created using scientific illustration service Biorender
https://www.chemistryworld.com/news/thousands-of-published-studies-may-contain-images-with-incorrect-copyright-licences/4020367.article
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Pauline Franz
Luc Reym⌬nd
about 1 year ago
Here is a starter pack dedicated to fluorescent probes, sensors and fluorophores makers. I'm sure it's incomplete, please reply to this post to be added or suggest someone.
go.bsky.app/MtgJE4w
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Pauline Franz
Stephan Hacker
about 1 year ago
Great to see so many new people from the scientific community joining here. Welcome! I would be very happy to connect with everyone on topics such as
#Science
,
#Chemistry
,
#Chemsky
,
#ChemicalBiology
,
#Antibiotics
,
#CovalentInhibitors
,
#ChemicalProteomics
,
#ABPP
and general topics of
#academia
.
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Pauline Franz
Lazare Saladin
about 1 year ago
Happy to see our latest work in ChemEurJ🎉. Here we present a new way to get a photoactivatable BODIPY for cell imaging. This probe allows super-resolutive images in the green channel. Special thanks to Valentine, Maxence, Pascal and Mayeul.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
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Targeted Photoactivatable Green‐Emitting BODIPY Based on Directed Photooxidation‐Induced Activation and its Application to Live Dynamic Super‐Resolution Microscopy
PFB is an efficient, green-emitting, photoactivatable probe based on BODIPY. Upon irradiation with visible light (488 nm), directed photooxidation oxidizes the furanyl group and eliminates the quench....
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202403409
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How to practice your
#storytelling
in
#science
? Originating from a workshop by
@mirkobischofberger.bsky.social
, Julius, Dani, and I started to develop the learning tool and game
#SciCubes
. Help us bring this project to life by ordering your set of🎲 here 👉
wemakeit.com/projects/sci...
THANK YOU!
almost 2 years ago
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Spreading chemistry 🧪 into biology 🌱 has been one of my primary motivators to start a PhD! I'm excited to share our review on how
#chemicalbiology
approaches have empowered the study of chromatin ubiquitylation! Here's the link to our
#OpenAccess
review
doi.org/10.1016/j.jm...
almost 2 years ago
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Pauline Franz
Carlos Moreno-Yruela
almost 2 years ago
Histone deacylases (#HDACs and
#sirtuins
) have specific and quite different ways of finding their targets through
#chromatin
🧬. Why do we know this, and what are we doing to study it in detail? All the info in our new review with
@beatfierz.bsky.social
! 👇🏻
portlandpress.com/biochemsoctr...
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Revealing chromatin-specific functions of histone deacylases
Histone deacylases are erasers of Nε-acyl-lysine post-translational modifications and have been targeted for decades for the treatment of cancer, neurodegeneration and other disorders. Due to their r...
https://portlandpress.com/biochemsoctrans/article-abstract/doi/10.1042/BST20230693/233949/Revealing-chromatin-specific-functions-of-histone
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Pauline Franz
Beat Fierz
almost 2 years ago
Check out the new review from
@carlosmyruela.bsky.social
on the using synthetic chromatin to investigate the function of histone deacylases!
doi.org/10.1042/BST2...
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Pauline Franz
Beat Fierz
about 2 years ago
Impressions from the LCBM Xmas party.!Happy holidays!!! 🎄🎁🎅🏽
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