Very pleased to share the 'last' first-author paper from my postdoc with Prof. Christian Heinis at EPFL. Now out in its final form in @angewandtechemie.bsky.social as a 'Very Important Paper' 🔥 (1/🧵) #chemsky onlinelibrary.wiley.com/doi/10.1002/...

My colleagues at Novo Nordisk have developed long-acting variants of PYY which, when combined with semaglutide, show promise in improving obesity and blood glucose regulation in preclinical models without muscle loss. Read more here: www.science.org/doi/10.1126/...

Exciting paper by colleagues at Novo Nordisk: a scalable method for C-terminal α-amidation of peptides & proteins. The protocol is highly relevant for the production of amidated peptide drugs such as amylins! #PeptideScience Read more here: www.nature.com/articles/s41...

Liver metabolizes high fructose corn syrup to fructose, which leads to increase production of LPC lipids that promote tumor growth. #Glycotime www.nature.com/articles/s41...

Happy to share a fun collaboration between EPFL and UCPH initiated by @carlosmyruela.bsky.social, Christian Heinis, @christianaolsen.bsky.social and I! Big shout-out to @danieladankova.bsky.social who spearheaded the project. Now out on @chemrxiv.bsky.social chemrxiv.org/engage/chemr...

Another great paper from #NovoNordisk on how housing mice near vs below thermoneutrality affects drug-induced weight loss because thermal stress greatly increases energy expenditure. Key to better evaluating data in the quickly growing field of obesity research! www.sciencedirect.com/science/arti...

Our Synthesis Tag (SynTag) for the synthesis of aggregating peptides and proteins is now published in JACS 🥳 Congratulations to first authors Héloïse & Elyse and everyone else involved ✨✨ pubs.acs.org/doi/10.1021/...

Are you curious to see what my team and I are up to? Check out our group website here: peptide-discovery.ethz.ch

🎨 In case anyone need… The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏! Check it out 👇 bioart.niaid.nih.gov

MIT researchers in collaboration with Novo Nordisk report in Nature an alternative to injections for the delivery of biologic drugs. This needle-free method leverages an ingestible capsule inspired by squids that releases drugs directly into the digestive tract wall. www.nature.com/articles/s41...

To tackle the challenge of proper glycaemic control for people on insulin therapy, my colleagues at Novo Nordisk have engineered a glucose-responsive insulin, which shows reduced activity at low glucose levels, thereby mitigating the risk of hypoglycemia. www.nature.com/articles/s41...