Reminder that, as of the latest reports, Liam Ramos is still in prison in Texas - now for 5 days. His parents are legal asylum seekers with no criminal record.

Clonal CD8+ T cells populate the leptomeninges and coordinate with immune cells in human degenerative brain diseases www.nature.com/articles/s41...

Where does Aβ come from in Alzheimer’s disease? 🔍 In this review, we explore Aβ production and functions of APP processing in non-neuronal cells as well as how targeting non-neuronal Aβ could lead to a more holistic disease prevention/targeting. link.springer.com/article/10.1...

📢Calling all @cam.ac.uk neuroscience students: Applications are still open to join our wonderful CamBRAIN team!🧠 This is a fantastic opportunity to get involved in the committee of one of the largest student neuro societies in the UK! More details in the comments👇 Apply by 26/01: lnkd.in/eMZ3P286

Huntington’s disease: treatments are finally on the horizon after research breakthroughs theconversation.com/huntingtons-... #Huntingtons #dementia #science #neuroscience #neurology

EBV is required for the development of multiple sclerosis, but it’s not known how a common virus leads to disease. 3 exciting new papers in @cellcellpress.bsky.social provide major insights into how this may occur:

Extremely interesting research and thread!

🚨 REGISTRATION NOW OPEN – CAJAL CONFERENCE 2026 “Novel Insights Into Brain Energy Metabolism in Health and Disease” 📍 April 15–17, 2026 | Cádiz, Spain 🔔 SENC Fellowships available
🔔 20 slots for Oral Communications 👉🏻 Register here: amconferences.eventsair.com/senc-cajal-c...
 👇🏻 SPEAKERS

The Cajal Conference 2026 on energy metabolism in health and disease in the wonderful city of Cadiz promises to be exceptional and exciting due to the impressive list of speakers. Registration with limited places is now open.

Mitochondrial transfer from glia to neurons protects against peripheral neuropathy @nature.com www.nature.com/articles/s41...

Glial progenitor cells, including OPCs, with IDH mutations (rather than neural stem cells) may be the cellular starting point for the development of IDH-mutant glioma. Science www.science.org/doi/10.1126/...

We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth. Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...

How is myelin remodelled without compromising myelin integrity??? www.biorxiv.org/content/10.6...

Comprehensive study looking at the genomic effects of chemotherapy on normal tissues. Somatic evolution following cancer treatment in normal tissue | Nature www.nature.com/articles/s41...

Textbooks said neurons don’t burn fatty acids for energy🤔. Our study delivers the first in vivo demonstration that fatty acid oxidation in defined memory neurons fuels memory formation. Closing chapter of my PhD 🥳, out today in Nature Metabolism💥 @natmetabolism.nature.com

Super congratulations to Sarah Moyon @neurosarah.bsky.social on this well-deserved achievement!!!

Super exciting news for the #OligOld team 🤩😱: our project Epiglia has been awarded an #ERCCog! Ready to dive into the epigenetics of oligodendroglial cells in Alzheimer for the next 5 years with our amazing group and collaborators @inp-marseille.bsky.social @univ-amu.fr

Longitudinal proteomic profiling of cerebrospinal fluid in untreated multiple sclerosis defines evolving disease biology www.nature.com/articles/s41...

Poor heart health in middle age linked to dementia in old age – new study theconversation.com/poor-heart-h... #Alzheimers #dementia #health #wellness

Looking forward to presenting our work on oligodendrocyte dysfunction in a rare neurodegenerative movement disorder X-linked Dystonia Parkinsonism. Come say hi if you're around on Tuesday, Nov 18 between 1-5 pm! @sfn.org #SfN2025 #SfN25

Local #mRNAtranslation in polarized cells is well studied in neurons but what about #microglia? This study shows that #inflammation enhances microglial #RNA localization & translation via RNA-binding protein IMP1/ZBP1, regulating morphology, motility & phagocytosis @plosbiology.org 🧪 plos.io/486ZLMS

📢 Interested in #lipidomics and #dementia? Join us tomorrow 👇

Últimos días para presentar candidaturas al Comité Científico Técnico de la @AgEInves. 📅 Plazo hasta el 10 de noviembre ℹ️ Procedimiento y detalles: www.aei.gob.es/sobre-aei/or... #Últimallamada #ComitéCientíficoTécnico #EvaluaciónCientífica

Join us at the last IBRO Connect of 2025 during #SfN2025. Connect with fellow #neuroscientists & join us in celebrating this year’s achievements in a fun atmosphere! 17 Nov | 19:00–21:00 PST at Venue 808, San Diego Limited seats: https://ibro.org/event/ibro-connect-networking-event-in-san-diego/

Thrilled to publish our new study on #mitochondrial ROS coming from complex III, revealing this key site in #astrocytes 🎯as a crucial immunometabolic signal transducer🤯 and potential therapeutic target for #dementia #FTD 💊 rdcu.be/eOc0m 👈💪 Great commentary by H. Pan and F. Yin🤩! tinyurl.com/4hdytw4c

@biorxivpreprint.bsky.social Regulatory T-cells in multiple sclerosis produce IL-10 in the central nervous system but are activated by Epstein-Barr Virus www.biorxiv.org/content/10.1...

Job offer! Join our lab in the beautiful Basque Country! 🌊🌍🧠📚👇🏻

If you think your field needs a collection of curated reviews and protocols, let me know! Let's create it and help the community.

Mark your calendars! The 28th Meeting of the French Glial Cell Club will take place Nov 17–20, 2026, in Sète. 🔹 Plenary lectures by Fiona Doetsch & Leda Dimou 🔹 5 symposia on glial diversity, astrocytes, human glia, EVs & modeling 👉 Full program available on our website: frenchglialcellclub.fr

WHITE MATTER IN FOCUS SYMPOSIUM: EXPLORING THE ROLE OF MYELIN AND OLIGODENDROCYTES IN NEURODEGENERATION neuroscience.cam.ac.uk/event-posts/...

The microscopy core at Miami University is searching for a new director. Please consider sharing this job posting! miamioh.wd5.myworkdayjobs.com/en-US/miamio...

Men’s brains shrink faster than women’s: what that means for Alzheimer’s nature.com/articles/d41... #Alzheimers #dementia #health #wellness #science

🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution. www.biorxiv.org/cgi/content/...

Interested in the heterogeneity of blood vessels in the CNS? Here we review the unique features of the spinal cord vasculature, its barrier properties and neurovascular interactions, highlighting unknown aspects and future research directions. @CRC1366 @erc.europa.eu @immunosens.bsky.social

“Using Human Brain Tissue in Research” NC3Rs supported @nc3rs.bsky.social Date & time: Friday, 7 November 2025 13:00–16:00 Prof Maria Thom Mr Martin Gillies Mr Ciaran S. Hill Location: UCL Institute of Advanced Studies Registration (event is free): www.eventbrite.co.uk/e/networking...

Another evidence for lactate influx, not efflux, in neurons. However, it suggests that in neonates, where levels of circulating lactate are high, lactate used by neurons is blood-derived, and that neonatal astrocytes might also use lactate. www.nature.com/articles/s41...

Prenatal Acetaminophen Exposure Does Not Disrupt Human Fetal Brain Development in Cortical Organoid Models https://www.biorxiv.org/content/10.1101/2025.10.07.681041v1

Alkalinization of glial cells increases lifespan and healthspan in C. Elegans www.science.org/doi/10.1126/...

Immune signatures link myelin oligodendrocyte glycoprotein antibody–associated disease to other autoantibody-mediated conditions www.science.org/doi/10.1126/...

Interested in #epigenetics #DNAmethylation #omics #Dementia #oligodendrocytes? Join us tomorrow👇

Myelin pathology is a key feature of X-linked Dystonia Parkinsonism https://www.biorxiv.org/content/10.1101/2025.10.07.680990v1

GlialCAM Cytoplasmic Signaling in Oligodendrocytes and Astrocytes is Essential for White Matter Homeostasis in the Brain https://www.biorxiv.org/content/10.1101/2025.10.03.680331v1

SV2A-PET imaging uncovers cortical synapse loss in multiple sclerosis | Science Translational Medicine www.science.org/doi/10.1126/...

What role does #myelination play in #PrefrontalCortex development? This study shows that juvenile #demyelination disrupts PV #interneuron firing & self-inhibition, revealing a developmental window where myelination is essential for long-term cortical function @plosbiology.org 🧪 plos.io/4mI4lVO

Remyelinated fibers have a distinct lipid profile compared to intact myelin www.sciencedirect.com/science/arti...

How are #circadian rhythms established during development? This study shows that maternal metabolic signals oscillate in the fetal #SCN before the endogenous #clock becomes functional, offering a plausible mechanism for maternal entrainment of the developing clock @plosbiology.org 🧪 plos.io/3VD45fZ

NeuroMAP @neuromarseille.bsky.social @univ-amu.fr organise une visite de laboratoire sur le campus de la Timone le 14 Novembre ! Venez rencontrer nos chercheurs 👩🏻‍🔬🧑🏽‍🔬 neuro-marseille.org/events/journ...

"Post-Synaptic Density Proteins in Oligodendrocytes are Required for Activity-Dependent Myelin Sheath Growth" www.sciencedirect.com/science/arti...

Progenitor Timing Shapes NG2-Glia Fate and Oligodendrocyte Differentiation https://www.biorxiv.org/content/10.1101/2025.09.24.678191v1

How do different tissues respond to mitochondrial dysfunction? @candrewfrank.bsky.social &co show that Complex I depletion triggers ROS-driven compensatory signaling in #MotorNeurons, but degeneration in muscles, with implications for #MitochondrialDisease @plosbiology.org 🧪 plos.io/4nLUIGJ