Marintia Nava-García
@marintianava.bsky.social
📤 449
📥 661
📝 9
Passionate about cell biology. PhD @ViennaBiocenter. Currently doing a postdoc at IGBMC.
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Marintia Nava-García
Gautam Dey
6 days ago
Thanks
@jcellsci.bsky.social
for this opportunity to contribute to your centenary collection with our take on the state of the field - 10 years after its modern reincarnation 🧪🌍 W/
@alebenoit.bsky.social
@eelcotromer.bsky.social
@fritzlaylin.bsky.social
journals.biologists.com/jcs/article/...
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Evolutionary cell biology comes of age
Summary: This Perspective discusses how the discipline of evolutionary cell biology, by integrating evolutionary theory, comparative physiology and modern molecular approaches, works to understand how...
https://journals.biologists.com/jcs/article/138/24/jcs264348/370175/Evolutionary-cell-biology-comes-of-age
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André Nadler
8 days ago
This opening statement made me actually open and read the paper. You all should, too. It's a wonderful piece of work. Thought-provoking in the best sense. It may very well be that Yamuna & team have found a proxy measurement for local metabolic activity. Which would be a game changer.
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Alice Ting
15 days ago
New work describes our efforts to achieve CRISPR editing of the mitochondrial genome.
www.biorxiv.org/lookup/conte...
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Towards CRISPR-based editing of the mitochondrial genome in yeast
Mitochondria, which evolved from symbiotic bacteria, possess their own genomes (mtDNA) and support independent transcription and translation within the organelle. Given the essential role of mtDNA in ...
https://www.biorxiv.org/lookup/content/short/2025.12.09.693232v1
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Gal Haimovich ☣ 🧪🔬🎗
15 days ago
this is amazing they show some compelling evidence for 3' to 5' translation
#RNASky
#RNABiology
🧪
www.biorxiv.org/content/10.6...
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3' to 5' Translation of Circular RNAs?
For decades, the 5' to 3' direction of translation has been a central dogma of molecular biology. Here we present evidence that eukaryotic circular RNAs (circRNAs) can serve as templates for 3' to 5' ...
https://www.biorxiv.org/content/10.64898/2025.12.08.692888v1
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Philipp Niethammer
16 days ago
Joe Shen’s and Zaza Gelashvili’s work on the role of the ER in nuclear membrane mechanotransduction finally came out in a journal!
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Endoplasmic reticulum disruption stimulates nuclear membrane mechanotransduction
Nature Cell Biology - Shen, Gelashvili and Niethammer developed an inner nuclear membrane tension sensor and demonstrated that ER–nuclear membrane contiguity acts as a mechanical buffer.
https://rdcu.be/eTQHX
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Buzz Baum
23 days ago
And another Asgard paper. Cells in motion! Wow!
www.biorxiv.org/content/10.1...
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Dynamic protrusions mediate unique crawling motility in Asgard Archaea (Promethearchaeota)
Crawling motility is a hallmark of eukaryotic cells and requires a dynamic actin cytoskeleton, regulated adhesion, and spatially organized signalling pathways. Asgard archaea (phylum Promethearchaeota...
https://www.biorxiv.org/content/10.1101/2025.11.30.690169v1?rss=1
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Marco Incarbone
23 days ago
Preprint alert! It is my great pleasure to announce the first manuscript from the lab, a story that started
@gmivienna.bsky.social
and was mainly accomplished by the intrepid
@gesahoffmann.bsky.social
at
@mpi-mp-potsdam.bsky.social
. A brief thread with our findings
www.biorxiv.org/content/10.1...
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AGO5 restricts virus vertical transmission in plant gametophytes
The propagation of a viral infection from a host parent to its progeny is known as vertical transmission, or seed transmission in plants. It allows viral infections to rapidly spread locally via polle...
https://www.biorxiv.org/content/10.1101/2025.11.28.691182v1
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Javier Espadas
24 days ago
New preprint from the lab!!🎉 We show that Asgard archaea ESCRT-III proteins can trigger membrane fission and reveal its molecular mechanism, offering clues to how these cells may have built internal compartments. But do these organisms even have these compartments?
www.biorxiv.org/content/10.1...
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Molecular basis for cellular compartmentalization by an ancient membrane fission mechanism
The emergence of cell compartmentalization depends on membrane fission to create the endomembrane compartments. In eukaryotes, membrane fission is commonly executed by ESCRT-III, a protein complex con...
https://www.biorxiv.org/content/10.1101/2025.11.28.690958v1
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Abdou Rachid Thiam
28 days ago
And the saga continues! Our collaborative work with outstanding Justin Korfhage & Thomas Melia’s lab in PNAS shows that ATG2A transfers triglycerides and does so bidirectionally! An exciting twist in our understanding of lipid transport. Definitely worth a deep read:
www.pnas.org/doi/10.1073/...
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Jana Helsen
29 days ago
How do new centromeres evolve while staying compatible with the division machinery? Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore. 👉
doi.org/10.1038/s41586-025-09779-1
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Johana Rotterova
about 1 month ago
Is it a flagellate? A tiny ball with tentacles? Contamination in my ciliate culture? NEW SUPERGROUP OF EUKARYOTES? Yes to all 4! Meet Solarion - just out in
#Nature
doi.org/10.1038/s415...
Huge congrats to Marek Valt, Cepicka Lab & the star team! Very happy to be part of this project.
#ProtistsOnSky
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Carmelo Ferrai
about 1 month ago
Great work from the lab of
@jojdavies.bsky.social
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
www.cell.com/cell/fulltex...
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Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
Li et al. apply base-pair resolution Micro Capture-C ultra to map chromatin contacts between individual motifs within cis-regulatory elements and reveal a unified model of biophysically mediated enhan...
https://www.cell.com/cell/fulltext/S0092-8674(25)01178-X
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Juanma García-Arcos
about 1 month ago
Launching
celldynamicslab.com
, the homepage of our new group at EPFL working on cell fragmentation, membrane and cortex mechanics, FLIM imaging, and microfluidics tools. MSc/PhD or postdocs interested in quantitative cell biology are welcome to reach out. We're also hiring a lab manager in 2026!
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Main - Cell Dynamics and Fragmentation Lab
The Cell Dynamics and Fragmentation lab at We study how single cells move and fragment in complex environments using microfluidics. We bring tools and concep...
https://celldynamicslab.com
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Gautam Dey
about 2 months ago
And just when you thought things were settling down, the enigmatic Asgard archaea have another surprise in store! Cell cycle/life cycle stage-specific internal compartments with almost no eukaryote-derived clues as to how they might function. Beautiful tomography and microscopy - congrats all 🤩
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Buzz Baum
about 2 months ago
We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.
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Tanmay Bharat
about 2 months ago
An Asgard archaeon with internal membrane compartments Brilliant study led by
@fmacleod.bsky.social
and Andriko von Kügelgen. Tight collaboration with
@buzzbaum.bsky.social
and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
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Pierre Bourguet
about 2 months ago
How is epigenetic information inherited? We found that CDCA7 proteins are critical players in the inheritance of DNA methylation at CG sites in plants, and this is true both in the lab and in the wild. How does this work? 🧵👇
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Caterina Giannini
about 2 months ago
Curious about my main PhD work?!🔬🌱 Please have a look on
@biorxivpreprint.bsky.social
biorxiv.org/content/10.1101/2025.11.04.686542v1
Connecting auxin-autophagy-development
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
about 2 months ago
🚨Our collaboration with
@centriolelab.bsky.social
&
@gautamdey.bsky.social
is out today in
@cp-cell.bsky.social
We show that
#Expansion
#Microscopy
is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky
#SciComm
#SciSky
www.cell.com/cell/fulltex...
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Gioele La Manno
2 months ago
🧠 The Lipid
#Brain
Atlas is out now! If you think
#lipids
are boring and membranes are all the same, prepare to be surprised. Led by
@lucafusarbassini.bsky.social
with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
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André Nadler
3 months ago
Lipid imaging on the cover of
@nature.com
! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article:
www.nature.com/articles/s41...
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Eric Topol
3 months ago
Exercising fathers, enhanced endurance and metabolic heath in offspring, through sperm microRNAs (as demonstrated in mice)
www.cell.com/cell-metabol...
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Paternal exercise confers endurance capacity to offspring through sperm microRNAs
Yin et al. show that paternal exercise improves offspring endurance capacity and metabolic health via sperm microRNAs that reprogram gene expression in early embryos, revealing how exercise benefits c...
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(25)00388-2
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Thibaut Brunet
3 months ago
Latest from ours:
www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
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Very happy and lucky to continue my scientific journey as a postdoc in the Sumara Lab! 🌞
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3 months ago
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Yale Cell Biology
3 months ago
Did you know that all nuclear pore complexes (NPCs) are not the same?
@luskinglab.bsky.social
propose a new hypothesis for how nuclear mechanics may impact the compositional plasticity of NPCs with implications for tissue-specific diseases caused by NPC dysfunction.
www.nature.com/articles/s41...
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Nuclear mechanics as a determinant of nuclear pore complex plasticity - Nature Cell Biology
In this Review, Lusk et al. discuss emerging insights into nuclear pore complex variability with regard to composition and dilation state, and propose nuclear mechanics as a key determinant of driving...
https://www.nature.com/articles/s41556-025-01768-w
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Itay Budin
3 months ago
Very excited to share new work out today in
@natchembio.nature.com
on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n)
www.nature.com/articles/s41...
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Leaflet-specific phospholipid imaging using genetically encoded proximity sensors - Nature Chemical Biology
An approach combining bioorthogonal chemistry with genetically encoded fluorogen-activating proteins enables subcellular imaging of phospholipids and glycans, as well as the visualization of lipid tra...
https://www.nature.com/articles/s41589-025-02021-z
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Wanlu Zhang
4 months ago
Excited to share the preprint from my postdoc work
@ellenberglab.bsky.social
! 🌟 During mitotic exit, cells rebuild thousands of nuclear pores within minutes. How do tiny holes expand to selective channels, and how is this coordinated with the nuclear envelope remodeling? 🔗
doi.org/10.1101/2025...
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Hydrophobic interactions of FG-nucleoporins are required for dilating nuclear membrane pores into selective transport channels after mitosis
Nuclear envelope (NE) reformation after mitosis is essential for daughter cell viability and requires tightly coordinated nuclear pore complex (NPC) assembly and nuclear membrane reformation. To revea...
https://doi.org/10.1101/2025.09.08.674396
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Nature Reviews Molecular Cell Biology
3 months ago
ICYMI: New Online! Structure, function and assembly of nuclear pore complexes
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Structure, function and assembly of nuclear pore complexes
Nature Reviews Molecular Cell Biology, Published online: 09 September 2025; doi:10.1038/s41580-025-00881-wRecent near-atomic structures of the nuclear pore complex provide insights into its assembly and function — how it acts as a selective permeability barrier, regulates nucleocytoplasmic transport such as mRNA export, and integrates mechanical forces experienced by the cell and nucleus.
https://bit.ly/4nqUQv1
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Jorge Ferreira
4 months ago
New preprint from the lab! Please check it out. 🚨 Have you ever wondered how cells decide when it’s time to divide? So did we!
www.biorxiv.org/content/10.1...
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Chromosome condensation mechanically primes the nucleus for mitosis
Timely and accurate transition into mitosis is essential to preserve genome integrity and avoid chromosome segregation errors. This transition depends on spatial and temporal activity patterns of the ...
https://www.biorxiv.org/content/10.1101/2025.09.01.673438v1
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Nature
4 months ago
For some three billion years, unicellular organisms ruled Earth. Then, around one billion years ago, a new chapter of life began
go.nature.com/3JyRV4S
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How did life get multicellular? Five simple organisms could have the answer
Single-celled species that often stick together in colonies have researchers rethinking the origin of animals.
https://go.nature.com/3JyRV4S
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Clausen Lab
4 months ago
big one! a decade in the making. nadler & team develop tools to track lipid transport in living cells at single-species resolution. turns out non-vesicular, asymmetry-driven transport is the main architect of organelle identity. feels like the dawn of a golden era for lipid biology.
rdcu.be/eBGJv
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Quantitative imaging of lipid transport in mammalian cells
Nature - Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.
https://rdcu.be/eBGJv
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André Nadler
4 months ago
Out today in
@nature.com
: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
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Journal of Cell Biology
4 months ago
Heffler and
@LammerdingLab.bsky.social
discuss recent studies from the
@schliekerlab.bsky.social
(
doi.org/10.1083/jcb....
) and
@hennelab.bsky.social
(
doi.org/10.1016/j.ce...
) that identify two proteins serving as crucial mechanical elements in the endoplasmic reticulum.
rupress.org/jcb/article/...
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Milena Schuhmacher
4 months ago
We are hiring! If you are looking for a postdoc position and you are interested in signaling lipids and proteomics, come join us in beautiful Switzerland! More information on
www.epfl.ch/labs/gr-schu...
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Open positions
GR-SCHUHMACHER
https://www.epfl.ch/labs/gr-schuhmacher/open-positions/
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Gautam Dey
5 months ago
Want to acquire
#ExM
images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
With
@dudinlab.bsky.social
@embl.org
@biology-unige.bsky.social
@moorefound.bsky.social
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Christian Fankhauser
6 months ago
Remarkable paper explaining how sea slugs maintain chloroplasts obtained by kleptoplasty active for many month & eventually digest them for resources
www.cell.com/cell/fulltex...
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A host organelle integrates stolen chloroplasts for animal photosynthesis
Sea slugs steal foreign chloroplasts and store them in specialized organelles that facilitate photosynthesis and eventual digestion to mediate starvation resistance.
https://www.cell.com/cell/fulltext/S0092-8674%2825%2900637-3
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Journal of Cell Biology
7 months ago
New study showing the development of pan-Expansion Microscopy by Morgan et al.
@luskinglab.bsky.social
to reveal the molecular composition and structural plasticity of individual nuclear pore complexes including LINC complex-dependent dilation.
rupress.org/jcb/article/...
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Gregor Mendel Institute of Molecular Plant Biology
7 months ago
Congratulations to Marintia Nava on the completion of her PhD! Marintia, a researcher in the Dagdas Lab, presented her dissertation titled “Characterization of a novel selective autophagy pathway for protein quality control in Arabidopsis thaliana” during her PhD defense.
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Matthias C. Rillig
7 months ago
Wow: check it out; these fungi distribute their chromosomes across different nuclei! Normally each nucleus has a complete set of all chromosomes. Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi | Science
www.science.org/doi/10.1126/...
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Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi
Nuclei define eukaryotes, enabling macromolecular compartmentalization and cellular regulation. Each nucleus is believed to contain one or more haploid sets of chromosomes (1N). However, we discovered...
https://www.science.org/doi/10.1126/science.abn7811?utm_source=sfmc&utm_medium=email&utm_content=alert&utm_campaign=SCIeToc&et_rid=35361117&et_cid=5616351
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Marintia Nava-García
9 months ago
✍️Our collaborative project with the
@becklab.bsky.social
(
@mpibp.bsky.social
) and the Kräusslich lab who applied innovative ultrastructural analyses to analyze nuclear pores in Nup133-/- embryonic stem cells and neural progenitors is now out
@naturecomms.bsky.social
! 🔗
www.nature.com/articles/s41...
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Nuclear pores safeguard the integrity of the nuclear envelope - Nature Cell Biology
Taniguchi et al. structurally analyse nuclear pore complex architecture in situ during differentiation, which is associated with mechanical constraints on the nuclear envelope. They link nuclear pore ...
https://www.nature.com/articles/s41556-025-01648-3
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Marintia Nava-García
Beck Laboratory
9 months ago
(1/3) Together with the labs of Valerie Doye
@vdoye.bsky.social
and Hans-Georg-Kräusslich, we analyzed NPC structure in Nup133 null mESCs. We found heterogenous NPCs featuring non-canonical symmetries and missing subunits. Now online
@naturecellbiology.bsky.social
.
www.nature.com/articles/s41...
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CIBSS – Centre for Integrative Biological Signalling Studies
10 months ago
It’s
#InternationalWomensDay
tomorrow! We took the occasion to talk to molecular biologist & CIBSS leadership team member
@kraftlabfr.bsky.social
about
#Equality
,
#CultureChange
and the power of mentoring and supportive networks in science. 📖 Read the full interview here:
kurzlinks.de/ndwd
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André Nadler
10 months ago
Are lipids actively sorted during clathrin mediated endocytosis like proteins?
@mathilda95.bsky.social
addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow.
www.biorxiv.org/content/10.1...
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Suayb Üstün
10 months ago
Wow! The Proteasome generates antimicrobial peptides that directly affect bacterial membranes
#proteostasis
www.nature.com/articles/s41...
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Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature
Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...
https://www.nature.com/articles/s41586-025-08615-w
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Austin E. Y. T. Lefebvre
10 months ago
Do you LOVE organelles?? Well I am THRILLED to announce that Nellie has been published in
@naturemethods.bsky.social
! Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy 🧵1/N
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11 months ago
It’s so nice to be able to celebrate something this week. Newest work from the group! How are nuclear contents delivered to the cytosolic autophagy machinery while maintaining nuclear integrity? Nuclear envelope gymnastics! Cool role for Dnm1/Drp1.
www.nature.com/articles/s41...
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A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope - Nature Cell Biology
Mannino et al. provide a quantitative and ultrastructural timeline of nucleophagy in yeast with lattice light sheet microscopy and correlative light and electron tomography. They identify a role for d...
https://www.nature.com/articles/s41556-025-01612-1
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Claudio Bussi
11 months ago
www.science.org/doi/10.1126/...
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Protein codes promote selective subcellular compartmentalization
Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that prote...
https://www.science.org/doi/10.1126/science.adq2634
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I am sure that Angelina will be a brilliant group leader and, more importantly, a great mentor 🎉
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11 months ago
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Lipid-CLEM!
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11 months ago
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Beck Laboratory
11 months ago
In a great collaboration with
@hummerlab.bsky.social
and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell:
authors.elsevier.com/sd/article/S...
@mpibp.bsky.social
@uniheidelberg.bsky.social
A thread below:
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