Reminder - a great job opportunity at @ucdavis.bsky.social Dean, College of Biological Sciences jobs.sciencecareers.org/job/676649/d...

New Title Alert: Protein-Hunter- a tool for exploiting structure hallucination within diffusion for protein design. A fast, fine-tuning-free framework for de novo protein design. Learn more here: buff.ly/DrCDsKH #SBGrid #StructuralBiology #SBGridSoftware

Tired of drawing cilia or centrioles for slides and papers? I feel you. Check out CiliaBuilder for ChimeraX → cxtoolshed.rbvi.ucsf.edu/apps/chimera... Build custom 3D cilia & centriole models (tips + primary cilia included).

Multiplex mapping of protein–protein interaction interfaces www.pnas.org/doi/10.1073/...

We're hiring for multiple open rank positions in the broad areas of biochemistry, molecular biology, and computational biology. With the recruitment of a new chair our Departmental strengths now include nuclear architecture, genomics and ancient DNA. jobs.sciencecareers.org/job/676677/b...

We have an opening for a research support officer. Come and join us! Please share.

New preprint! We found that the flavin-dependent halogenase RebH catalyzes sequence-tolerant Trp bromination in peptides 🧪https://www.biorxiv.org/content/10.64898/2025.12.17.694899v1

Ever wondered how TIMELESS/TIPIN can sit at the leading edge of the replication fork regulating its speed, but also bind polymerases and ssDNA/RPA in replication stress? We have an idea how it might work! Check out our new preprint, any feedback is highly appreciated! www.biorxiv.org/content/10.6...

Multidisciplinary training, over time, produces the highest impact people www.science.org/doi/10.1126/...

Very important 🧵 🧪 Amplifying for greater reach

Chromatin buffers torsional stress during transcription | Science www.science.org/doi/10.1126/...

Looking for a faculty job at one of the world's great research stations? We're looking for a marine invertebrate biologist at UW's Friday Harbor Labs. apply.interfolio.com/178804

Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us! We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK! Sign up here: meetings.embo.org/event/26-arc... #ArchaeaSky

Talin didn’t evolve for integrins... integrins evolved for talin 🤯 pN force coupling via talin is ancient, conserved from amoebae to humans; signaling came later. Read this amazing paper here 👇🏽 www.nature.com/articles/s41...

Awesome to see Ye's work from my lab featured on the cover of @rnajournal.bsky.social 's January issue! It's an awesome story about 3' splice selection and how Prp8 and Prp22 may communicate with one another! The structure shown is @maxewilkinson.bsky.social 's P complex (9DTR)

Our latest paper on the molecular mechanisms of XPF-ERCC1 recruitment to SLX4-dependent DNA repair pathways has been published! Congratulations to first author Junjie Feng, and a heartfelt thank you to all our collaborators for their contributions to this study! www.nature.com/articles/s41...

📢 Telomere community: Registration and abstract submission are now open for the EMBO Workshop “Telomere function and maintenance in health and disease”, May 25–30, 2026, in Lazise, Italy 🇮🇹. Looking forward to an exciting meeting! Please re-post. meetings.embo.org/event/26-tel...

NIGMS R35 Maximizing Investigator's Research Award (MIRA) for Outstanding Investigators new NOFO is available!! Submission dates starting in January 2026 through May 2028. See link below: simpler.grants.gov/opportunity/...

1/ I’ve reviewed hundreds of bioinformatics GitHub repos in my career. Here’s the brutal truth: most tool documentation fails the people it’s meant to help. And it’s not because the algorithms are bad.

@pravrutharaman.bsky.social got super intrigued about EZHIP/CATACOMB, previously identified as a histone H3K27M mimic of PRC2. You can read about her efforts here: www.biorxiv.org/content/10.6... We hope these analyses will help spur more analyses in this very cool gene! 1/

Just got word that we are a go for the Bacterial Cell Biology and Development GRS and GRC at Southern New Hampshire University! GRS will be on June 5-6, 2027 GRC will be from June 6-11, 2027 Block off your calendars Prokaryotic Cell Biologists! More details to come! Please repost!

Can one map the genome-wide binding (1) and its protein partners (2) simultaneously from the same sample? Yes, one can. with CUT&ID ✂️🪪 Spearheaded — singlehandedly — by @annanordin.bsky.social No need of transgenesis, cloning and overexpression. Check it out, it's fast and its works.

We are hiring a lab manager, for our research group, the Synthetic Neurobiology group (aka Boyden Lab) at MIT/HHMI (on the MIT campus, Cambridge, MA)! Please apply if you're qualified and interested, and spread the word! hhmi.wd1.myworkdayjobs.com/External/job...

An early Christmas present for those interested in chromatin and transcription! Fantastic work from @au-ho-yu.bsky.social and @aleksszczurek.bsky.social . Thanks to Inge and Michiel for their help. Please repost! www.biorxiv.org/content/10.6...

I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...

We are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!

The Gonzalez Lab at Columbia University is seeking a scientific leader! Join us in a Research Scientist position, driving single-molecule, structural, and biochemical studies of translation, translational control, and other RNA-based processes. Apply: apply.interfolio.com/176949

PRIorI: a graph-based mining of structural arrangements in protein-protein interfaces https://www.biorxiv.org/content/10.64898/2025.12.03.692053v1

Star student & postdoc Kiarash Jamali is setting up his own group at the Ellison institute in Oxford. Join him for the most exciting machine learning research in structural biology and beyond!! 🤩 #ProudPI

I’m excited to announce that I will be starting my research group on computational enzyme design at the Generative Biology Institute, Oxford, UK (@eitoxford.bsky.social)! PhD applications are open, deadline is Jan 8th (www.chem.ox.ac.uk/genbio-dtp). Email [email protected] with any questions!

Iowa State Dept of Molecular Biology is hiring for biomolecular solution NMR facility staff #NMRchat #Chemjobs #Chemsky (I am NOT the hiring manager for this position, but I will refer any questions you have to the appropriate person.) isu.wd1.myworkdayjobs.com/IowaStateJob...

@science.org 🧬🔬 Multiscale structure of #chromatin condensates explains phase separation and material properties | Science www.science.org/doi/10.1126/... @janhuemar.bsky.social et al.

Over the past century, quantum mechanics has served as the foundation for modern physics theories, including quantum field theory. The theoretical groundwork is now being transformed into new disciplines. Learn more in a new special issue of Science: https://scim.ag/4oz1y2a

Come join our team! The deadline is December 7, but the application is quick. Only a cover letter, CV, and a short Research Highlight are needed #chemsky #chemjob #chembio

Mapping single-cell diploid chromatin fiber architectures using DAF-seq - @uwgenome.bsky.social @uwdeptmedicine.bsky.social go.nature.com/4rFTAHy

Williams, Schekman et al. show that human cells shed extracellular vesicles in order to repair their membranes. rupress.org/jcb/article/... 📕 From The Year In Cell Biology: rupress.org/jcb/collecti... #CellBio2025

New @natcomms.nature.com paper today from Tracy Bryan's lab @cmri.bsky.social: "Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase". Happy our lab could play a small part. Congrats Tracy, Ash Harman, Noa Lamm and the whole team. www.nature.com/articles/s41...

579 high-quality human genomes from @humanpangenome.bsky.social, Arab Pangenome and individual papers (CHM13, CN1, KSA001, I002C, YAO and KOREF1). Sequences available in the AGC format (3.7GB) and FM-index in the ropebwt3 format (20.3GB). For details, see github.com/lh3/human-asm

Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions: Mentoring Profile raising Leadership training Network building Spread the word... www.biologists.com/grants/devel...

❄️The 2026 Winter Session of GIIN Webinars is here! Join us on the first Tuesday of each month at 5 PM (Rome) / 11 AM (NYC). No pre-registration needed, simply join via Zoom: uniroma1.zoom.us/j/95149984403 Want reminders? Subscribe here: docs.google.com/forms/d/e/1F...

Latest from Whitehead Institute's AI Fellow Na Sun 👇 Learn more about her work at the intersection of AI and biology: shorturl.at/K1AXP

Jay Bhattacharya and Matthew Memoli aren't bringing "gold standard science" to the #NIH, they are gutting research slowly but surely. When this time is over, they should be hauled before Congress, and shunned for the rest of their lives. www.nytimes.com/interactive/...

The world has lost a giant of virology, molecular biology and science advocacy David Baltimore’s obituary by Stephen Goff www.nature.com/articles/d41...

Our next extraordinary biologist is Grace Lim, a prolific preLighter @prelights.bsky.social and a contributor to @the-node.bsky.social and @dev-journal.bsky.social. #100biologists

How to keep in step when your (protein) partner speeds up… Here we investigated the adaptive remodeling of a protein-protein interaction surface essential for telomere protection. Congrats to whole team! www.science.org/doi/10.1126/...

The newly discovered archaean 𝘚𝘶𝘬𝘶𝘯𝘢𝘢𝘳𝘤𝘩𝘢𝘦𝘶𝘮 𝘮𝘪𝘳𝘢𝘣𝘪𝘭𝘦 has a genome with 238,000 base pairs, far fewer than humans (billions) or 𝘌. 𝘤𝘰𝘭𝘪 (millions). The species was named after Sukuna-biko-na, a Shinto deity known for being tiny.

Exciting collab with Paul Palme, Peter Imming, & Adrian Richter! Guided by @courbongautier.bsky.social's structure of myco ATP synthase bound to a squaramide, they have made SQAs that are less toxic, more potent, more stable than AstraZeneca's SQ31f #MedChem #TB #NTM pubs.acs.org/doi/full/10....

www.nature.com/articles/s41... Progressive coevolution of the yeast centromere and kinetochore 🤩 @helsenjana.bsky.social @gautamdey.bsky.social

We are recruiting a postdoctoral fellow to study mechanisms of DNA replication stress using single-molecule imaging tools. If you are excited about microscopy, replisome dynamics, and genome stability, we’d love to hear from you. Application deadline: 24 December www.crick.ac.uk/careers-stud...

Registration for #APSPM2026 closes soon. Everyone’s welcome! whether you study evolution, structure, or computational methods, join us in Brisbane (and online) Feb 16–18, 2026 to learn how protein structure meets phylogenetics. biosig.lab.uq.edu.au/strphy26 @official-smbe.bsky.social