Make some noise about this 🧪 www.npr.org/2026/06/03/n...

WHY?

SPLICECRAFT v1.0 IS LIVE!!!!!!!!!!!! Open your terminal and type in "pipx install splicecraft" if you want to try it out, then spam "splicecraft update" often as I push updates frequently. A labor of love for the community I adore. Enjoy! 💚

Exam question idea: give a question with AI answering it. The student needs to explain what is wrong with the AI answering.

Night market in Santa Clara this weekend!!! www.santaclaraca.gov/recreation-c...

Evolution of my print. Printing TPU 85a is way harder than I expected.

I accidentally made a better stirring system

Much needed good news www.canarymedia.com/articles/cle...

Either I like to eat scorpions or I don’t…

Claude is way better anyway

Mass surveillance and killer robots are not for me.

My new cup holders, which change color when heated.

🔭🛰️🧪

Exciting! Stanford researchers have developed a UNIVERSAL INTRANASAL vaccine. A study in mouse models shows that vaccinated mice were protected against Covid & other coronaviruses. Still a long way to humans. This study was #NIH funded. A potential game changer. 🧪 med.stanford.edu/news/all-new...

The system acts as near-permanent archival storage for backup of critical data. It stores 4.8 terabytes, the equivalent of around 2 million printed books Data survives for 10,000 years at a temperature of 290ºC and much longer at room temperature. 🧪🦠 www.nature.com/articles/d41...

I suspect one reason science social media has done reasonably well post-Twitter is that it didn't get (too badly) scattered. There's a viable population on both Bluesky and Mastodon. Here's one (opt-in) way of of connecting those two populations to make sciencesky even bigger. 🧪

🧪⚛️ Ever wondered what would happen if you thrashed around in a water tank, creating a blob of turbulence, and then watched it spread and gradually dissipate energy? So did we. But we did the experiment, now out in PNAS and on the cover! It only took us 7 years ... www.pnas.org/doi/10.1073/...

Why is Windows do this every time my computer updates?

Okay, but for #BlueSky to gain a fraction of the value in networking that we once enjoyed over at #Twitter, we all need to be reposting pretty much everything we see. Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky url: academic.oup.com/icb/article-...

🤞

Another cool pipette rack pattern!

Wow. This is devastating. www.science.org/content/arti...

Another 3d printed pipette rack

My new pipette holder

This figure really grabs your attention!

Is there an easy way to get saw RNA-seq data and turn it into a table of differentially expressed genes? Like, without installing 12 programs and taking a bioinformatics course?

I hope their antibodies are better than their legos. The design is very flimsy, but I enjoyed the challenge.

Taaaaalllllll

Surprise mother$#@%er! Q: What does this mean for neural systems to understand them? A: We absolutely need the wiring diagram. All synapses, chemical and electrical. #Connectomics

They win for best use of parafilm: www.nature.com/articles/s41...

👀

How to write an R01 type grant that isn’t “too high risk”, but is still exciting, novel?

This is VERY cool! 🧪

Son got sick (severe cold) in Taiwan, no insurance. Saw a doctor in 10min, $15 including the acetaminophen and ibuprofen the doctor gave us. How much would that be in the USA?

More squirrel.

This website was meant for scientist runners! They literally cut the shoes in 1/2 and do all sorts of testing on them! runrepeat.com/saucony-ride...

PI sharing with his student a competitor's ERC that he's reviewing

Wow, this is really cool! www.nature.com/articles/s41...

Update, I grabbed 10 colonies and combined into one @plasmidsaurus.bsky.social reaction. All of them were too small and most were the same, the TE inserted in the same place. So screening colonies won't likely work.

Boolean logic-gated protein cargo release! @coledeforest.bsky.social's group previously used the molecular topology with proteases as inputs to release fluorescent proteins from hydrogels, and they now extended the platform for other protein cargoes! 🧬 onlinelibrary.wiley.com/doi/abs/10.1...

Has anyone had this show up in their plasmid, and how to prevent it? "E. Coli IS10L Transposon"

AI can mess things up real fast! 😭

I tried to "squeeze gel purify" DNA, sent it for sequencing, and it worked! ~Protocol: 1) cut out band 2) poke hold in small tube, put gel in it, put in big tube 3) Spin for 2-3 seconds 4) sequence the liquid in the bottom tube This may not always work, but cool! @plasmidsaurus.bsky.social

iGEM is not your typical scientific conference! @igemcommunity.bsky.social

“Bang-Bang optimal light control for maximum protein production in yeast” - love this title hal.science/hal-05323963...

So many beautiful pictures and I love papers that benchmark a bunch of tools.

If you want your research to sound “basic”, call it “basic research”. - I don’t think the general public will think it is very important. I like “fundamental science” better. Today I saw “frontier science”, which sounds cooler and more important.

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

A paper in Nature Communication reports on a new method to produce strong, biodegradable plastic from bamboo. The bioplastic resembles oil-based plastics in strength, shapeability, and thermal stability but can biodegrade in soil within 50 days. go.nature.com/4h1xv0X 🧪