Congratulations Pete, Zach, and team!

Congratulations @genlichem.bsky.social and Xiao! Very clever probe design.

My work assessing the effect of preorganization on dihydrazide activity is out in @jacs.acspublications.org. We find that dihydrazides with flexible tethers can replicate much of the catalytic activity of complex dihydrazides with preorganized foldamer scaffolds. #Chemsky doi.org/10.1021/jacs...

Excited to share a new pre-print on a joint study between my group and @chembiobryan.bsky.social‬! Directed Evolution of Enzymes for Bioorthogonal Chemistry Using Acid Chloride Proximity Labeling. chemrxiv.org/engage/chemr... 1/n

Really proud of Riley's preprint on a new class of chiral Lewis acid photocatalysts. This project benefitted from a terrific collab with @chemguyeli.bsky.social chemrxiv.org/engage/chemr...

Excited to share our new preprint, which was years in the making! chemrxiv.org/engage/chemr... New reactions are typically developed by trial and error. How can we speed up this process? Read on to learn how we used DNA scaffolding to perform >500,000 parallel reactions on attomole scale. 1/n

Despite ~20 years in/around #chembio research, I went to my first Bioorganic GRC this week. This community is amazing and so supportive. I feel energized (and tired, lol) and find myself rooting for the next generation of chemical biologists. Sooooo much awesome science - We can’t/won’t be stopped!