Ulcerative colitis induces stem- and effector-like γδ T cell subsets influencing therapeutic response @sciimmunology.bsky.social www.science.org/doi/10.1126/...

2/ Bioinformatics isn't just data processing. It’s not: “Load → Analyze → Publish.” It’s exploration, interpretation, ITERATION. It’s art.

This #MucosalMonday @bainlab.bsky.social and @lizihegarty.bsky.social are in the Authors Corner discussing their recent #macrophage work from MI. Then @kknoop.bsky.social brings you more allergy and anaphylaxis with Caroline Sokol and @stephanieeisen.bsky.social: www.iheart.com/podcast/269-...

Tools 'To address this knowledge gap, we developed “cytokine cellular locating platforms” (CyCLoPs), a reporter system that translates cytokine receptor engagement into a genetically traceable signal.' #Immunology www.cell.com/cell/abstrac...

279 postdoctoral fellowships! Download freely our database of postdoctoral fellowships and grants. For each entry, we provide eligibility criteria, $ amount, deadline, etc. Good luck! Here: research.jhu.edu/rdt/funding-...

2026 is here! We’re excited to share Global Immunotalks first semester poster, featuring an outstanding lineup! Please share and help us spread the word!

Here's a summary of all the data that supports adding more red meat to your diet

Nature research paper: Neuro-epithelial circuits promote sensory convergence and intestinal immunity go.nature.com/4qeRjlt

Colonic macrophage heterogeneity revealed by CD11c and CD163 www.mucosalimmunology.org/article/S193...

Re-submitting the paper to other journals

💥New paper alert!💥 What’s better than starting 2026 with an @annualreviews.bsky.social #Immunology, often a once-in-a-life honor ❤️?! Check it out if you want to know everything about type III interferons #IFN! Thanks to my wonderful team for their amazing work 🤗 doi.org/10.1146/annu...

@drjonlim.bsky.social & @reisesousalab.bsky.social show cDC1s & DNGR1 favor "tethered" neoantigens from F-actin proteins, trapping them in necrotic debris for better cross-presentation! Calls for prioritizing these neoantigens for cancer vaccine design #Immunotherapy www.nature.com/articles/s41...

On the use of murine models: Results should be interpreted with caution. Batf3-deficient mice have been traditionally used as a model to study the function of cDC1; however, this transcription factor seems to play other essential roles in other immune populations👇

Blog post: Just quit Quitting projects in science is hard, but we should be doing a lot more of it. open.substack.com/pub/arjunraj...

Now online! Gut microbiota promotes immune tolerance at the maternal-fetal interface

We wrote two reviews on cell migration, published today in Nature Methods. They provides practical guidelines how to select a cell-migration assay and how to analyze cell-migration data Review 1: nature.com/articles/s41... Review 2: nature.com/articles/s41...

The issue features The neutrophil collective, a Review focusing on both traditional properties of neutrophils and those that challenge existing dogmas. www.cell.com/cell/fulltex...

Urs Mörbe, William Agace et al. characterize and spatially map the fibroblast landscape within human large and small intestinal gut-associated lymphoid tissues, including Peyer’s patches and isolated lymphoid follicles, during homeostasis and #Crohns disease. rupress.org/jem/article/... #IBD

Have you heard about the Night Science Podcast, where we talk about the creative process of doing science? We explore this with discussions with brilliant scientists & philosophers and artists, to figure out the tricks of the creative scientific trade. podcasts.apple.com/us/podcast/n...

Human gut M cells resemble dendritic cells and present gluten antigen @nature.com @hansclevers.bsky.social www.nature.com/articles/s41...

🎉 Registration is NOW OPEN! 🎉 We’re excited to welcome you to next year’s International Conference on Innate Lymphoid Cells, where leading experts, innovators, and researchers will come together to share insights, spark collaborations, and shape the future of ILCs and beyond. #ILC6 (1/3)

Macrophage-toxic bacteria from patients with ulcerative colitis worsen gut inflammation in mice @science.org www.science.org/doi/10.1126/... www.science.org/doi/10.1126/...

..cross your 't's folks.. here's how! www.nature.com/articles/s41...

My thoughts on Rosalía’s ‘Lux’ and the complicated symbolism of classical music

Raise a glass for Rosalind Franklin tonight and honor her memory and scientific contributions

Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n openrxiv.org/enabling-rev...

🧬 Excited to share Nicheformer out now in Nature Methods! A transformer foundation model linking single-cell & spatial omics, learning spatial context from gene expression to map tissue organization. Led by Ale Tejada & Anna Schaar 👏 👉 www.nature.com/articles/s41...

What happens to our immune system with aging, reducing vaccine response? Our memory T cells undergo a dramatic shift resulting in dysregulated B cell antibody production @alleninstitute.org @nature.com www.nature.com/articles/s41...

Researchers in #ScienceTranslationalMedicine present a new method to generate stable, antigen-specific regulatory #Tcells in large quantities using the body’s own conventional T cell pool, and show the resulting cells can treat IBD and GvHD in mouse models. https://scim.ag/47dDYBm

Arai, Kawakami, Sakaguchi (2025 #Nobel laureate) and colleagues show that oral antigen exposure combined with CD28 costimulation blockade generates functionally stable antigen-specific CD101⁺ pTreg cells even in previously antigen-sensitized hosts. rupress.org/jem/article/...

Latest in our #WomenInSTEM series from researchers discussing their science and the process of setting up a lab as an independent researcher, as well as the unique challenges they face as women scientists in their respective scientific environments: rupress.org/jem/article/...

When Macrophages Disappear, Skin Blood Vessels Age! Check out our new study @nature.com that uncovers how the loss of capillary-associated macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology 👇👇 www.nature.com/articles/s41...

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

Happy to share new work from #theonlylabever, lead by the phenomenal @sltai.bsky.social - who developed a tool to study the biology of ILC3s, identifying their role in controlling CSF2-dependent myeloid cells. 🤗 @mucosalimmunol.bsky.social @societymucosalimm.bsky.social OA: doi.org/10.1016/j.mu...

Congratulations to new Nobel Laureate and AAI Distinguished Fellow Shimon Sakaguchi, co-winner of the 2025 Nobel Prize in Physiology or Medicine for his foundational discoveries on regulatory T cells and peripheral immune tolerance! Published in The JI in 1995: ow.ly/LGk150X7984.

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" Stay tuned for more. #NobelPrize

Interested in learning how to be a good speaker and give effective talks? Season 2 of the NYC Postdoc Night Science Club begins October 15th. Join us NYC Postdocs for a 2hr workshop and maybe also a drink at a bar! Free registration (usually ~100 come): docs.google.com/forms/d/1dII...

📢 📢📢📢 📢 Mechanosensitive fibroblasts fuel strictures via YAP/TAZ signaling—opening doors to new anti-fibrotic therapies. Grateful to be part of this transformative study with the Longaker lab! 🙏🙏🙏 www.sciencedirect.com/science/arti... STAY TUNED for more in IBD damage from the #Naiklab

This looks like an amazing fix and I will definitely try. The overnight transcription factor staining protocol was already a game changer and I recommend it to everyone.

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

Review @natimmunol.nature.com Microbiota-mediated mechanisms of mucosal immunity across the lifespan www.nature.com/articles/s41...

After many years of work I’m so happy to share our work on #scienceimmunology on how Treg cells modulate nociception to dampen skin inflammation! My handle will make a lot more sense now!🕵🏻‍♀️

Discovery of the number of ways cancer cell hijack other cells to promote their growth and spread keeps proliferating www.cell.com/cell/fulltex...

Excited to share our new preprint! We studied how T cells are functionally & clonally shaped across organs over time. With the new TRACK mice, we genetically label recently activated T cells with tdTomato and track their migration across tissues. #immunology #science www.biorxiv.org/content/10.1...

🚨 New article! Our study "Human monoclonal antibodies protect against death caused by mpox" is now published: 👉 www.cell.com/cell/fulltex... [1/9]

Looks interesting! www.nature.com/articles/s41...

Also on #IUIS2025 Day 3: keynote by Ruslan Medzhitov. Pet shop mice have pre-existing immunity (look at the size of those LNs!) and a crowded "antigenic space" with Th1/17/reg immunity. Allergic sensitization in SPF mice is possible because the antigenic space is available for full blown Th2

Hey everybody! @drjuliawester.bsky.social and I have a new paper! We surveyed over 800 scientists, science communicators, and science educators who use social media. Conclusion: Scientists no longer find Twitter useful or pleasant, and many have switched to Bluesky! 🧪🌎🦑 doi.org/10.1093/icb/...

1/ Excited to share the first preprint from my lab! 🎉 My postdoc Paz asked how cholera toxin (CT) helps Vibrio cholerae thrive in the gut. Turns out, CT rewires epithelial metabolism toward L-lactate production—fueling pathogen growth in the small intestine during disease