David McKellar
@dwmckellar.bsky.social
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RNA Tech Dev Romix Bio | Tech Inno @ NYGC | PhD @ Cornell BME | postbac @ NHGRI mckellardw.github.io
reposted by
David McKellar
Waggoner Lab
about 2 months ago
Spatial transcriptomics maps host–gut microbiome biogeography at high resolution
www.nature.com/articles/s41...
@natmicrobiol.nature.com
@dwmckellar.bsky.social
@ntekasi.bsky.social
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reposted by
David McKellar
Yannis Ntekas
about 2 months ago
Our work with Lena Takayasu and
@dwmckellar.bsky.social
in Iwijn De Vlaminck's lab is now out in
@natmicrobiol.nature.com
! 🎉 Spatial transcriptomics maps host–gut microbiome biogeography at high resolution
rdcu.be/e7i7o
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Still time to sign up for this event next week! So far, across the ~120 registrants we have 7 academic institutions, 4 companies, and 2 journals represented!
add a skeleton here at some point
11 months ago
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Not a bad spot to talk science...
12 months ago
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Very excited to announce the first **RNA x Tech Dev Mini-Symposium** in collab with the Tri-I RNA Club! Talks from Chris Mason, Ildar Gainetdinov,
@xuebingwu.bsky.social
, and Sanja Vickovic! Come down to
@nygenome.org
and hear about the latest in RNA technology development being done in NYC!
12 months ago
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Happy Single-Cell Genomics Day!
#SCGD25
satijalab.org/scgd25/
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Single Cell Genomics Day
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https://satijalab.org/scgd25/
about 1 year ago
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A window into the future of diagnostics from one of my favorite scientists,
@alexpellancheng.bsky.social
. Awesome work!
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about 1 year ago
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Very cool work from the team at Kanvas on HiPR-Map!
www.biorxiv.org/content/10.1...
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Multiscale Spatial Mapping of Microbial Communities for Biotherapeutic Development
Live biotherapeutic products (LBPs) are emerging as powerful tools to modulate the microbiome using well-defined microbial communities. Yet, designing, manufacturing, and delivering LBPs remains chall...
https://www.biorxiv.org/content/10.1101/2025.03.31.646377v1
about 1 year ago
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Designing/building a Toyota is just as hard as a designing/building Ferrari in biology
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about 1 year ago
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reposted by
David McKellar
Itai Yanai
over 1 year ago
📢New Yorkers! We're meeting for the second session of the 'Postdoc Night Science NYC' club on January 30th 5-7pm. This time we'll be at NYU (Washington Square campus), with the topic of 'A hypothesis is a liability'. Space is limited so please register:
docs.google.com/forms/d/1Shc...
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reposted by
David McKellar
Matthew Alexander, PhD
over 1 year ago
And without further ado, the top muscle paper for 2024 as voted on by you is: 1. Sequeira et al., Dev. Myonuclear position and blood vessel organization during skeletal muscle postnatal development.
tinyurl.com/bduvtpa8
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Myonuclear position and blood vessel organization during skeletal muscle postnatal development
Summary: A comprehensive analysis of the first 20 days of mouse skeletal muscle postnatal development focusing on myonuclear positioning and interactions of myonuclei with blood vessels.
https://tinyurl.com/bduvtpa8
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reposted by
David McKellar
Neville Sanjana
over 1 year ago
Delighted to share new work from our lab: MultiPerturb-seq 🎛️ ❌ ↕️ Over the last few years, we've been combining CRISPR screens with multimodal readouts of gene expression (RNA) and chromatin accessibility (DNA). In this study, we bring those together within the same cells.
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Come talk RNA with us!
add a skeleton here at some point
over 1 year ago
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reposted by
David McKellar
Yannis Ntekas
over 1 year ago
Spatial structure shapes the host-microbiome interactome. Our new method to map the host-microbiome interface at high-resolution, now on bioRxiv! Co-led with Lena Takayasu &
@dwmckellar.bsky.social
collab between the De Vlaminck and Brito labs
doi.org/10.1101/2024...
A thread⬇️
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High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing
Inter–microbial and host–microbial interactions are thought to be critical for the functioning of the gut microbiome, but few tools are available to measure these interactions. Here, we report a metho...
https://doi.org/10.1101/2024.11.18.624127
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