www.nature.com/articles/s41... Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy

A game changer in our hands... www.nature.com/articles/s41...

Thrilled to announce the launch of my lab @cri-utsw.bsky.social at UTSW this January! We will explore how cells sense and respond to mechanical forces, focusing on membrane mechanics to reveal how tension and signaling work together to shape cell behavior.

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

Cell-surface DNA - wowser! 🧬❤️

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues. www.biorxiv.org/content/10.1...

#Micorscopy community, does anyone know where I can order this type of bottle from? Or even what the proper name is for them?

Our new paper, in collaboration with Bristol Myers Squibb, on a Natural Killer cell immune therapy, is just published here: www.pnas.org/doi/10.1073/... #immunesynapse #nkcells #immunetherapy #microscopy

Check out this excellent paper from Khodor Hazime and @dandavis101.bsky.social! It's got NK cells, it's got engagers, plus super-resolution microscopy!

'Novartis is buying the rights to potential cardiovascular medicines from a Chinese biotech in a deal worth up to $5.2bn, as big pharmaceutical companies become increasingly reliant on Chinese innovation to replenish their drug pipelines.'

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...

This is such a great work! Congratulations to everyone 🥳🥳🥳

Durable B-Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis onlinelibrary.wiley.com/doi/10.1002/...

✨We’ve just launched our new guide to #vaccinations during #pregnancy! Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond. Download a copy for trusted information: bit.ly/4fuRqVw

Engineering B cells to treat and study human disease www.nature.com/articles/s41... @natbiotech.nature.com

How do lipids shape life? I explore this question in my recent talk for the Build-a-Cell 🦠 seminar series. Thanks to @kateadamala.bsky.social for hosting! Watch it here: youtu.be/JnF7hPCiSbI?...

We’re excited to share a new pre-print from the lab! Led by Carmen Ramirez Moncayo and a fantastic collaboration with several groups from across @mrc-lms.bsky.social & @imperialcollegeldn.bsky.social. Interested in #OvarianCancer, #PARPinhibitors or #DrugDistribution? please read on! bit.ly/45lpekS

Very glad and honored to contribute to this cool study. Check out the latest story on my favorite protein "NINJ1": www.nature.com/articles/s41...

This Friday, UK Cell Motility Club symposium in Cambridge, UK: exciting PhD student and Postdoc speaker line up! A few last minute spots available. Follow us on @uk-cmc.bsky.social cytoskeleton.wixsite.com/londoncellmo...

I did my PhD using flies as a model system🩷. FlyBase is amazing, without it my PhD would be much more painful. I can’t imagine it stopping its existence 😥. Sharing for greater reach! Please donate 🙏

David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏 youtu.be/8YhJM6zxYDw?...

Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse @pnas.org @katelynspillane.bsky.social www.pnas.org/doi/10.1073/...

Here come our new palette of fluorescent dyes. The BD dyes endeaves to balance glowy brightness, robust photostability, and biocompatibility. Let's boost 4D dynamic super-resolution imaging!!! www.nature.com/articles/s41... @spirochrome.com

Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis: Immunity www.cell.com/immunity/ful...

🧠🍔 Just 48 hours on a high-fat diet can weaken gut immunity. Our new study shows saturated fats rapidly impair ILC3s! Proud to see this featured by @wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!

Looking forward to the Physics within the Cell workshop on 16th June. Join if you want to discuss molecular motors and intracellular transport with me. More info here: iop.eventsair.com/pwtc2025/

New paper out today in @pnas.org from Hannah, Anna, and Maro showing that antigen mobility influences the speed, probability, and precision of B cell antigen extraction in the immune synapse. @annbajur.bsky.social @maroiliopoulou.bsky.social www.pnas.org/doi/epdf/10....

Yes, that is me, for those who did not yet know. This was not planned but I am very happy to go 'home' even though I will miss a lot about Portugal. If you still want to visit, hurry, otherwise see you in Cambridge. If you want to know more contact me directly. www.pdn.cam.ac.uk/news/dr-care...

Really happy that my main PhD story is out! Huge thanks to everyone involved - especially @nadlerlab.bsky.social - for giving me the opportunity to work on this amazing topic.

Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...

B cell-derived acetylcholine promotes liver regeneration by regulating Kupffer cell and hepatic CD8+ T cell function (if you still doibt that B cells are super important 🙃) www.cell.com/action/showP...

The time is now to register! Early Bird Registration Deadline is May 1st, 2025, for the #AdiposeBiology Conference happening in Montreal, Quebec, Aug 19 & 20th, 2025. Go to: www.adiposebiology.com to secure your spot today! #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social

Very excited to see the first Beisaw lab publication out in its final form 🥳🥳 rdcu.be/ei1I7 if you’re interested in zebrafish heart regeneration and how cardiomyocytes replace the fibrotic injured tissue (spoiler alert: macrophages play an important role), then read it here 👇

An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in RA www.nature.com/articles/s41...

oh sad news

Just discovered this (somehow never saw it before), it's 8 years old, but still very up-to-date, and covers many aspects of what I do/want to do and what inspires me. I think it's also a cool listen for everyone not (yet) into mechanobiology, but just curious: 👉 wyss.harvard.edu/media-post/d...

New #MathOnco preprint now out from talented PhD student Nic Fan (not on Bluesky)! We explore how adding a friction term into agent based models for tumour growth leads to some quite cool effects (including allowing some nice simulation of vascular occlusion) www.biorxiv.org/content/10.1...

PhD on offer at Kew: Plants and their Products: Biocultural collections at Kew Gardens & the South Kensington Museum during the long nineteenth century If only I could apply! Fascinating mutual interests of Kew and the V&A in plants. Closes 16 May www.royalholloway.ac.uk/studying-her...

That's a wrap on the first full day at #DPG spring meeting in Regensburg! Many more interesting things to come this week. If you'd like to chat about forces, mechanics or synbio tools in living tissues, come find me at my poster (BP17.76) tomorrow night!

Press release on the self-driving multiscale microscope from @daetwylerstephan.bsky.social et al: www.utsouthwestern.edu/newsroom/art...

Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow. www.biorxiv.org/content/10.1...

Exciting discovery by Svensson lab and collaborators @stanfordmedicine.bsky.social, computational discovery of 2500 new bioactive peptides, including 12-mer named BRP that reduces food intake leading to weight loss w/o nausea in mice! www.nature.com/articles/s41...

Registration is open for the 2025 iteration of the wonderful @EMBOevents workshop on cell polarity and membrane dynamics #EMBOcellPolarity25 I am organizing with Ed Munro! Wonderful lineup wonderful please please sign up and share! meetings.embo.org/event/25-cel...

Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U

Your dignity honors the bravery of the Ukrainian people. Be strong, be brave, be fearless. You are never alone, dear President Zelenskyy. We will continue working with you for a just and lasting peace.

🇺🇦 ❤️