Jie Yang
@jieyang437.bsky.social
📤 136
📥 443
📝 4
Group Leader of Cancer Immunology University of Oxford
One week left to apply for the postdoc position in my lab at Oxford
@ox.ac.uk
Join our exciting cancer immunology research at
@oncology.ox.ac.uk
,
@oxfordcancer.bsky.social
&
@oxcio.bsky.social
. Deadline: 11 August 2025 (noon).
add a skeleton here at some point
4 months ago
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We're recruiting a postdoc to join my lab at
@oncology.ox.ac.uk
&
@oxcio.bsky.social
to understand immune regulation in cancer and develop new approaches for cancer prevention and metastasis. Deadline: 11 August 2025
my.corehr.com/pls/uoxrecru...
Lab info:
www.oncology.ox.ac.uk/team/jie-yang
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Job Details
https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10&p_refresh_search=Y&p_display_in_irish=N&p_process_type=&p_form_profile_detail=&p_applicant_no=&p_internal_external=E&p_recruitment_id=180940&p_display_apply_ind=Y
4 months ago
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reposted by
Jie Yang
Roychoudhuri Lab
8 months ago
New results from the ALASCCA prospective randomised controlled trial showing daily
#aspirin
reduces colorectal cancer recurrence by ~50% in patients with PIK3CA or related mutations. Findings extend benefits of aspirin beyond Lynch syndrome cancers to nearly 40% of CRCs
ascopubs.org/doi/10.1200/...
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Low-dose aspirin to reduce recurrence rate in colorectal cancer patients with PI3K pathway alterations: 3-year results from a randomized placebo-controlled trial.
LBA125Background: Colorectal cancer (CRC) affects 1.9 million individuals globally each year. Among patients with stage II-III CRC, 20-40% develop metastatic disease. Aspirin lowers the incidence of a...
https://ascopubs.org/doi/10.1200/JCO.2025.43.4_suppl.LBA125
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reposted by
Jie Yang
Roychoudhuri Lab
8 months ago
Research Highlight of our recent paper by
@jieyang437.bsky.social
on Aspirin and cancer metastasis in Nature Reviews Immunology. Thanks to Yvonne Bordon for a crystal clear account of the experimental findings
www.nature.com/articles/s41...
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Aspirin helps T cells to stop cancer spread - Nature Reviews Immunology
Drugs like aspirin can enhance the anti-metastatic activity of T cells by blocking a platelet-mediated pathway of suppression.
https://www.nature.com/articles/s41577-025-01160-7
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reposted by
Jie Yang
Seth Coffelt
9 months ago
Congrats to
@jieyang437.bsky.social
& Rahul for this awesome work on metastasis
www.nature.com/articles/s41...
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Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity - Nature
Inhibition of cyclooxygenase 1 releases T cells from immunosuppression by platelet-derived thromboxane A2, thereby enhancing the immune response against metastasis.
https://www.nature.com/articles/s41586-025-08626-7
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reposted by
Jie Yang
Klaus Okkenhaug
9 months ago
Brilliant new paper from Jie Yang
@jieyang437.bsky.social
and Rahul Roychoudhuri
@roychoudhurilab.bsky.social
linking aspirin to immune-mediated prevention of cancer metastasis.
www.nature.com/articles/s41...
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Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity - Nature
Inhibition of cyclooxygenase 1 releases T cells from immunosuppression by platelet-derived thromboxane A2, thereby enhancing the immune response against metastasis.
https://www.nature.com/articles/s41586-025-08626-7
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