We have two open PhD positions at the Ernst-Ruska-Centre of the Forschungszentrum Jülich on amyloid fibril structure determination by cryo-EM. Find more information here: www.schroderlab.org/jobs.html

Trump has insulted and tariffed his European allies, persuaded Denmark to prepare for a US invasion and, by pressuring Ukraine and not Russia, encouraged Putin to keep fighting. All of which he has forgotten. www.theatlantic.com/ideas/2026/0...

New on bioRxiv 🧪 📄 A fresh look at how domain-specific ligand binding controls TRPM2 activation ⛓️‍💥 This work disentangles the roles of distinct nucleotide-binding domains and their contribution to gating — a long-standing question in the field.  👉 www.biorxiv.org/content/10.6... @embl.org

Our latest @biorxivpreprint.bsky.social: "Prion-like transmission of human tau strains in the mouse brain" 🥳 With Michel Goedert and Masato Hasegawa. www.biorxiv.org/content/10.6...

ROCKET 🚀 inference-time optimization of AlphaFold to fit structural data is published! rdcu.be/fa9YH Since our preprint, we’ve pushed it to regimes where other methods break: low resolution, weak signal, real experimental edge cases. Here’s what we learned: 1/15

A 60-year-old climber from the Czech Republic died on March 27 while climbing on the Greek island of Kalymnos, one of the world’s leading sport climbing destinations, after several bolts failed, raising - again - the issue of aging equipment. gripped.com/news/rock-cl...

David Attenborough reveals that “some British gardens are almost as diverse as a tropical rainforest” and that “our gardens cover a greater area than all of our national nature reserves combined”. www.theguardian.com/tv-and-radio...

Do we grow wiser as we age? I spent 15+ years chasing glam journals, wasting time and energy (and frustrating my team and co-authors). I don’t want to wake up at 70 and realize my life went into convincing a few editors my work was trendy enough. Enough. I’ll try to be smarter.

Added a little script to chimerax-trimmings to automate the creation of panels for model-map fit figures. It zones the map around (by default) 40aa parts of each chain (but doesn't cut in the middle of helices). Saves each as a png, metadata to csv. Saves each view as a scene for tweaking views.

The newly established NeCEN Utrecht is looking for a #cryoEM scientist! www.uu.nl/en/organisat... Work with a new Krios 5 + pFIB and support cutting-edge life science research. 📍 Utrecht | 🗓 Apply by 30 April Please share with your network!

I'm grateful for having been featured, together with Holger Heyn, in one of the main Sunday supplements in Spain (XL Semanal). Check out here how we talked all about the implications of single-cell atlases for understanding biology! www.hoy.es/xlsemanal/ci... @hoheyn.bsky.social

The last 11 years have been the hottest years ever recorded. Earth’s energy imbalance has reached its highest than at any time in observed history, with heat reaching deeper into the ocean. This is the Global #StateOfClimate 2025. 📰 Press release: https://bit.ly/4ds4r2V #WorldMetDay

Weak.

Surface ice ruining your cryo-ET lamellae? We showed you can sublimate it away — inside the SEM, no extra hardware, no devitrification. 🧊→✨ New preprint from @KarolinskaInst 3D-EM 🧵👇

Denmark and allies were flying in blood products and preparing for blowing up the airstrips as Trump threatened Greenland in January. Surprising no-one the 'exercise' Arctic Endurance was in fact an active operation, planned since 2025 with France, Germany and Nordics (+UK?).

We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo. #OpenSoftwareAcceleratesScience

If you consider 'hiring’ AI instead of a graduate student, you're saying the quiet part out loud: PhDs are viewed as a PI's labor force not academics studying for an advanced degree... www.science.org/content/arti...

Holy smoke. What ultimately happened???

Hi Fabio, the facility in Umeå does. You can find info including facility contact here (I am a user but I don't work at the facility): www.umu.se/en/research/...

Hello BlueSky Community, do you know of any European Cryo-EM facility which possess a High-pressure freezer being used under BSL-2 safety level? The sample would be a bacterial biofilm.

Just ONCE I want to travel by train @deutschebahn.com in Germany without delays, missed connections and cancelled trains. Today was not that day. I'll keep trying. Still beats driving by a long shot!

If you ever want to read a paper for free and can't find it otherwise, email the lead author and politely ask for a copy. You will not be bothering the person. You will in fact make their whole entire day. I have had scientists get so excited I asked they sent me everything they ever published.

When someone says „Scientists do not want you to know“ you can dismiss everything from there on. Scientists want you to know. They are desperate that you know. They can’t shut up about what they found out and want you to know.

Let's not forget that the convicted rapist Donald Trump is in the Epstein Files.

Question for the #cryoEM crowd: have you played with ModelAngelo, CryoAtom and EMProt, and would you care to offer thoughts/notes on the comparison? I have ModelAngelo installed and I love it, but the other two claim improved performance - which should I try first?

Very proud of Bader Rayan for leading this work uncovering RNA as a regulator of peptide assembly and phase behavior, reshaping the bioactivity of virulent amyloids and host-defense peptides at the interface of bacterial virulence and innate immunity. In @elife.bsky.social: doi.org/10.7554/eLif...

We paid tribute to the fallen heroes of Ukraine at Maidan. I am also thinking of their comrades, bravely holding the line in the trenches. Fighting for peace. Fighting for a better future for their children. Fighting for a free and sovereign Ukraine, at the heart of a free Europe.

Four years have passed since Russia's full scale invasion of Ukraine. Russia was supposed to win in three days. Instead, Ukraine reinvented modern warfare, built a drone industry, and can destroy a thousand Russian soldiers in a day. Ukraine can win.

I’m embarrassed that I cheered for this group of absolute assholes.

This is the kind of thing a rich CEO says at the beginning of a science fiction movie to establish for the audience that he is a sociopath and the villain.

I LOVE when science is applied to "toddler questions" like "Why is the sky blue?" or "Why is ice slippery?" Because the answers can be so SUPRISING. Let's dig into recent revelations about how ice skates work & why tires skid across black ice. First, we'll dismiss 3 VERY GOOD hypotheses as wrong.

The amyloid packing difference (APD) is a new metric to compare amyloid structures. Analysis of disease-specific structures provides context for the interpretation of APDs for new comparisons. I hope it will be useful! 🤗 www.biorxiv.org/content/10.6...

Whoah. This hits hard: unreplug.com/blog/dear-mi...

An early career researcher asks Nature Careers for advice on what to do when their idea shared in a poster presentation is published by someone else. #Academicsky 🧪

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳 mrc.tal.net/vx/mobile-0/...

I had Claude make this as a mini-game for Relay's disconnect screen (like Chrome's dinosaur), but then pivoted to stand-alone. In this game, you have to find Euler angles matching the target projection, i.e. cosplay RELION. It can be pretty hard. Works on mobile too! warpem.github.io/euler-hunt/

I am excited to share our latest preprint - An evolutionarily divergent herpesvirus with a giant tail. Featuring symmetry breaking and genome annotation from structure using ModelAngelo. doi.org/10.64898/202...

After a 12 year wait, the best players in the world are again playing in the Olympics. Let's fucking go! #icehockey #trekronor #olympics

🎉 Happy International Day of Women and Girls in Science 🔬 Some of our group leaders shared insights into what they love most about their jobs in science. ❤️ CSSB supports women and girls in science through initiatives like Girls‘ and Boys‘ Day. #WomenInScience @landaulabcssb.bsky.social

Amazing sprint, the Swedish women crushed the opposition! 🥇🇸🇪🥈🇸🇪🥉🇸🇪

omg everybody go draw a horse this is what the internet was made for gradient.horse

What a fantastic start to the Winter Olympics! 🇸🇪🥇Frida Karlsson 🇸🇪🥈Ebba Andersson

It’s a lonely job, leading a research group (professor, principal investigator, group leader – whatever you call it). You talk all day with everyone, but you’re mostly alone with the doubts and risks of the biggest decisions. Does it have to be though?? podcasts.apple.com/us/podcast/n...

Oh our Minneapolis, I hear your voice Singing through the bloody mist We’ll take our stand for this land And the stranger in our midst Directed by Thom Zimny Edited by Thom Zimny and Samuel Shapiro Production Footage: Pam Springsteen and Thom Zimny

Here's another deep field image from JWST. There's something pretty amazing hidden within it, which I'll talk about next. But open up this image and lose yourself in this almost impossibly vast view of our Universe. The six-pointed features are stars in the Milky Way. Everything else is a galaxy.

Archaea may not be well known, nor well studied, but these microorganisms can live in the most extreme environments, but also right on our skin. They’re everywhere. EMBL researchers are now exploring their unique ecosystem adaptability and link to evolution. www.embl.org/news/science...

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good. Stay free

And now out in Nature Comms (congrats Wyatt et al.): www.nature.com/articles/s41....

Andreas #Boland's group and collaborators diagnosed a rare genetic disease (ATTR) using a simple skin biopsy. This work paves the way for new diagnostic methods for degenerative diseases. @mocel.bsky.social @sciencesunige.bsky.social @natcomms.nature.com www.unige.ch/medias/en/20...