New preprint out!📃 This work uncovers how the clathrin adaptors Ent5 & Sla2 undergo LLPS, revealing distinct structural drivers that shape endocytic and trafficking dynamics. @lucasdefelipe.bsky.social @katharinchen.bsky.social @embl.org @cssbhamburg.bsky.social 👉 www.biorxiv.org/content/10.1...

New paper from our postdoc @fedevignale.bsky.social, et.al! Studying microbialites in Argentina 🇦🇷, they show how extreme, early Earth-like conditions shape microbes, minerals & biosignatures- insights for Earth’s past and life beyond 🌎 🧬. 👉 www.nature.com/articles/s43... @embl.org @ebi.embl.org

We’re looking for a GL! Join us at EMBL Hamburg! 🧫🦠🧬 The position will be based at CSSB @cssbhamburg.bsky.social , an interdisciplinary research centre focused on infection biology, and will be integrated into EMBL's research programme. @embl.org Find out more and apply here: lnkd.in/dJU9pee7

At EMBL Grenoble, lead an independent research group using bold, original approaches to integrate complementary structural biology methods with emerging nano X-ray imaging technologies, bridging scales and modalities to unravel molecular mechanisms. embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

Check it out the latest open position to join EMBL in Heidelberg! @embl.org

Congrats to the Grünewald, Topf groups & et. al @cssbhamburg.bsky.social on their Nature paper! 📃 🍾 Trapping and resolving the elusive prefusion form of HSV gB - neutralizing HSV-1 & HSV-2 with a single nanobody is no small feat!🦙 Glad that our SPC facility have contributed to this [email protected]

Excited to be part of the Instruct Centre Germany! @jankosinski.bsky.social @landaulabcssb.bsky.social @topf-lab.bsky.social @carobarisch.bsky.social @bosse-lab.bsky.social @spcembl.bsky.social

Exciting to be with part of my group at the 15th European Biophysics Congress (EBSA) in beautiful Rome, Italy 🇮🇹 If you are around, join my talk today about tools for the analysis of biophysical data 💡🧩 Check our posters for open discussion and networking !📃🖇️ @embl.org @cssbhamburg.bsky.social

KinGenie, an online tool for the analysis of kinetics data, has been introduced on the 4th MOSBRI Scientific Conference in Paris, France 🇫🇷 A great addition to our eSPC web server💡🚀 Reach out to us for further input! @osvalb.bsky.social @mosbri.bsky.social @embl.org @cssbhamburg.bsky.social

4th MOSBRI Scientific Conference starts today 📍in beautiful Paris, France 🇫🇷 Excited to see familiar and new faces from our TNA site, network and continue collaborating on research infrastructures projects in molecular biophysics 🧬🧫 🤝 @mosbri.bsky.social @embl.org @cssbhamburg.bsky.social

Happy to co-host a workshop on lipid nanoparticles together with @embl.org Hamburg this week. The workshop is a part of the @eugloh.bsky.social ‘Entrepreneurship meets Health Innovation at Large-Scale Facilities’ conference. @landaulabcssb.bsky.social @spcembl.bsky.social

Our latest research is out 📄 ! This study provides an interaction map of Sla2 & the regulatory proteins Sla1 & Pan1, predicted by AI modeling & confirmed by molecular biophysics. @lucasdefelipe.bsky.social @meytallandau.bsky.social @emilgustavsson.bsky.social @embl.org @cssbhamburg.bsky.social

🔊 Thrilled to share our latest work, just published in NAR! 📃 We present ChiraKit, open-source tool to process raw CD data and perform advanced analysis! Access via our eSPC web-server! ➡️ spc.embl-hamburg.de @osvalb.bsky.social @lucasdefelipe.bsky.social @embl.org @cssbhamburg.bsky.social

Just want to say thanks to @spcembl.bsky.social for developing ChiraKit and allowing quick and informative analysis of CD data - more here www.biorxiv.org/content/10.1... best news of the day today as we were stuck with beautiful but hard to analyze data 🙂 #scienceisawesome

We're hosting an Ask Me Anything about Biophysics on Bluesky today with BPS Ambassador Alumnus Gonzalo de Prat Gay! Tweet your questions with #BiophysicsAMA and tune in at 11am USA Eastern time.

🚨The registration for the Functional #Amyloid Meeting is finally open, check it out on landau-cssb.de 🧪🧬🧶

Congratulations to George who had his PhD defense today! 🥂🍾🥳🎉 @uni-hamburg.de @embl.org @cssbhamburg.bsky.social

Happy International Women's Day! #IWD2025 We encourage everyone to #AccelerateAction and support #DEI. @carobarisch.bsky.social @landaulabcssb.bsky.social @topf-lab.bsky.social @mariarosenthal.bsky.social @bosse-lab.bsky.social @jankosinski.bsky.social

🚨 New preprint alert 🚨! 👉🏼 @fedevignale.bsky.social 🏔️ Our latest study explores seasonal biogeochemical variations in a modern microbialite reef at Laguna Pozo Bravo 🇦🇷 - a site with conditions reminiscent of early Earth 🌍🦠 📖 Read here : doi.org/10.1101/2025... @embl.org @cssbhamburg.bsky.social

If you’re attending the BPS 2025, don’t miss the poster of our ARISE fellow @osvalb.bsky.social He’s presenting eSPC, online data analysis platform on biophysics ! 🔎 Date : 18/02/25 Time : 13:45 Session: “Protein stability folding & chaperones” Poster : B38 @embl.org @cssbhamburg.bsky.social

Looking forward to making new connections at #BPS2025👨 Meet me at poster B38 on Tuesday 18 Feb 13:45. Session "protein stability folding and chaperones"

Today,on #InternationalDayOfWomenAndGirlsInScience, we celebrate the contributions of women in structural biology & biophysics! As an international team of women scientists 🇦🇷 🇷🇺 🇩🇪 🇻🇪 , we’re proud to push the boundaries of discovery 🧬🦠 #WomenInSTEM #ScienceForAll @embl.org @cssbhamburg.bsky.social

Scientists at University of Buenos Aires, EMBL Hamburg, and others mapped yerba mate’s genome, providing surprising facts about its biochemistry and evolution of caffeine biosynthesis. 🧉🧬🧪 Find out more: www.embl.org/news/science... @spcembl.bsky.social

Exciting work on the Yerba mate (Ilex paraguariensis) genome providing new insights into convergent evolution of caffeine biosynthesis 🧬🧉 Amazing work from our postdoc Federico Vignale and our STO @lucasdefelipe.bsky.social @embl.org @cssbhamburg.bsky.social 🔗 elifesciences.org/articles/104759

After many months of gathering user feedback and improving our software, we think it's time to share it with the community. Enjoy our latest tool 🥳 , and stay tuned for the next one 😉

🔊 Our latest biophysical tool for circular dichroism analysis, ChiraKit, is out 🔍 To read more about it, visit www.biorxiv.org/content/10.1... ChiraKit can be accessed at spc.embl-hamburg.de @osvalb.bsky.social @lucasdefelipe.bsky.social @embl.org @cssbhamburg.bsky.social @mosbri.bsky.social

Yerba mate makes the third-most popular caffeinated drink in the world, but it’s unrelated to tea and coffee. The first reconstruction of its genome is helping us understand how multiple species have evolved to synthesise caffeine. https://buff.ly/4jnWk82

Congratulations to the Sondermann Group and our core facility user, Sophia Mortensen, and collaborators. Amazing work on the discovery and characterization of this new family of bacterial enzymes named as diDNases. @embl.org @cssbhamburg.bsky.social 🦠🧬

📣We are looking for an enthusiastic postdoctoral candidate to work on an interdisciplinary project on biophysics of extremophiles! 🤝A collaboration with Donato Giovannelli @donatogiovannelli.bsky.social and Vikas Trivedi @viktri08.bsky.social 📩Contact: [email protected]

Don’t forget to register for the new @embl.org /@EMBO symposium on Mechanisms of drug resistance and tolerance in bacteria, fungi, and cancer! Abstract submission: 12 Jan 2025 Registration (On-site): 4 Feb 2025 Date: 18 - 21 Mar 2025 Location: EMBL Heidelberg www.embl.org/about/info/c...

Happy holidays! Best wishes from the SPC Facility & EMBL HH @embl.org @cssbhamburg.bsky.social

What about joining us for an interdisciplinary postdoc between Hamburg,Naples&Barcelona working on the biochemistry and biophysics of extremophiles?!

Our SPC core facility at EMBL Hamburg has been awarded the Bronze level on sustainability and efficiency as part of the LEAF programme 🏆 ! We’re committed to engage in our lab work while reducing waste, recycling ♻️ , saving energy 🔌 and help our planet 🌏 ! @embl.org @cssbhamburg.bsky.social

Congratulations to our SPC facility user, Karthi Dhamotharan and the Schlundt Lab, for such an achievement on SARS-CoV-2 nucleocapsid protein and RNA binding 🦠🧬 Well done ! 👍 @embl.org @cssbhamburg.bsky.social

📣We are looking for an enthusiastic postdoctoral candidate to work on an interdisciplinary project combining Biochemistry of extremophiles and Structural Biology! 🤝The position will be held in collaboration with Donato Giovannelli and Vikas Trivedi ! 📩Contact: [email protected]

New preprint alert 🔔 ! New insights into the clathrin-mediated endocytosis machinery! Sla2 emerges as a central hub interacting with Clathrin Light Chains and the Pan1/End3/Sla1 complex. Read the full study: doi.org/10.1101/2024... #embl @cssbhamburg.bsky.social @lucasdefelipe.bsky.social

🔊 I am delighted to share our latest paper “Subtleties in Clathrin heavy chain binding boxes provide selectivity among adaptor proteins of budding yeast” Our publication ⬇️ rdcu.be/dZujI