Lucas A. Defelipe
@lucasdefelipe.bsky.social
📤 107
📥 259
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Senior technical officer @ EMBL Hamburg. Biophysics and Structural Biology
reposted by
Lucas A. Defelipe
SPC Facility & Garcia-Alai Lab
8 months ago
🔊 Thrilled to share our latest work, just published in NAR! 📃 We present ChiraKit, open-source tool to process raw CD data and perform advanced analysis! Access via our eSPC web-server! ➡️ spc.embl-hamburg.de
@osvalb.bsky.social
@lucasdefelipe.bsky.social
@embl.org
@cssbhamburg.bsky.social
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reposted by
Lucas A. Defelipe
SPC Facility & Garcia-Alai Lab
11 months ago
🔊 Our latest biophysical tool for circular dichroism analysis, ChiraKit, is out 🔍 To read more about it, visit
www.biorxiv.org/content/10.1...
ChiraKit can be accessed at
spc.embl-hamburg.de
@osvalb.bsky.social
@lucasdefelipe.bsky.social
@embl.org
@cssbhamburg.bsky.social
@mosbri.bsky.social
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reposted by
Lucas A. Defelipe
Osvaldo Burastero
about 1 year ago
Just out! 🥳🥳 Great work done at the
@spcembl.bsky.social
to understand clathrin-mediated endocytosis. We investigated how clathrin and adaptor proteins interact in vitro and in vivo. Kudos to the 1st author
@lucasdefelipe.bsky.social
!
www.nature.com/articles/s41...
www.embl.org/news/science...
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reposted by
Lucas A. Defelipe
SPC Facility & Garcia-Alai Lab
about 1 year ago
New preprint alert 🔔 ! New insights into the clathrin-mediated endocytosis machinery! Sla2 emerges as a central hub interacting with Clathrin Light Chains and the Pan1/End3/Sla1 complex. Read the full study:
doi.org/10.1101/2024...
#embl
@cssbhamburg.bsky.social
@lucasdefelipe.bsky.social
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Sla2 is a core interaction hub for Clathrin Light Chain and the Pan1/End3/Sla1 Complex
The interaction network of Sla2, a vital adaptor protein in the endocytic mid-coat, undergoes constant rearrangement incorporating or replacing interacting proteins over time. Sla2 serves as a scaffol...
https://doi.org/10.1101/2024.11.14.623549
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