Thank you for coming to my TED Talk 🎤 If you’ve read this far and still need convincing, please check out our preprint arxiv.org/abs/2511.04820 and this infographic: doi.org/10.5281/zeno... 10/10

As I worked on this #sciart piece this weekend, it got me curious about the origin of the mouse strains we use in biomedical research today: so welcome to my rabbit hole! A 🧵

This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social Day 19/31 Prompt ARCTIC Pdb: 3UYU Meet ice-binding protein (LeIBP) from Arctic yeast that acts like antifreeze! Next: RIVALS Suggestions?

Painted some xylem for a thing. Pretty pleased. #sciart

Thrilled to share this work from my postdoc with Tom Carmichael, available online @ Neuron! Long story short: we find even more evidence that all reactive astrocytes are not equal, and we can take advantage of those differences to improve repair after stroke. www.sciencedirect.com/science/arti...

PREACH! www.nature.com/articles/s41...

Paper Alert!! Our collaborative work with Giger Lab at UMich is out now in #ScienceTranslationMedicine Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury | Science Translational Medicine @science.org www.science.org/doi/10.1126/...

🧪🥤Researchers find Canada’s first sugary drink tax lowered odds of consumption nearly 25% New report highlights the potential of the tax to improve public health @avisfavaro.bsky.social www.heartandstroke.ca/what-we-do/m...

Very sorry to hear of Jane Goodall’s passing. Her scientific contributions and her work as a conservationist are extraordinary. #goodall #chimpanzee #conservation #primatology 🧪 Gift article

Occasional PSA: Intracellular molecular processing, especially in neurons, is not about differential RNA expression or even protein abundance for that matter. Not about quantity. It’s about qualitative, functional states. The sooner we get there as a community the faster the science advances

10/10 use of Lego bricks!

new out in Nature www.nature.com/articles/d41...

After a #stroke, patients typically undergo extensive #rehabilitation and a slow journey to recover the ability to do everyday tasks. However, ASNR Past President Dr. Tom Carmichael is developing a drug to produce the same effects as rehabilitation and could augment or replace rehab after a stroke.

Scientists discover the secret behind the shrew’s amazing ability to shrink their brains 🧠 The clever trick sheds unwanted weight without compromising too much on cognition. Find the 5-letter word 👇 Study by @cecibaldoni.bsky.social Dechmann Lab #shrewcrew et al www.ab.mpg.de/743885/news_...

New review from Lennol, @maudgratuze.bsky.social and colleagues @inp-marseille.bsky.social assesses all the available evidence regarding how two crucial elements are intertwined in #Alzheimers disease pathophysiology: tau and apoE. rupress.org/jem/article/...

Discovery happens less when you're trying to be the expert and more when you're trying to be the learner.

Rainbow retinas! While at @mblscience.bsky.social I had the opportunity to check out frog and octopus retinas using super neat birefringence microscopy invented by Michael Shribak, with student Jenna Tijerina. The vertebrate inner retina is so optically clear compared to the outer segments! 🧪🐸🐙👀

New pre-print on sex differences in the choroid plexus- the 🧠's fluid secretion organ. Important differences in secretory signaling & immune compartments that can impact the 🧠 in health & disease. ‪@karol-kaiser.bsky.social‬@violesilvar.bsky.social‬ Luca von Allmen. 🧪 www.biorxiv.org/content/10.1...

Last year I calculated how much money it cost to use my bike as my primary mode of transportation. It was less than 2k, and that’s on the high end for most people, as I don’t do much of my own maintenance. #YEGbike

this is your periodic reminder that young neuroscientist Zoe thought that the "squid giant axon" was actually the "giant squid axon" and it will forever make me giggle

"It didn’t happen overnight, but Paris is forever changed, and now local residents of the French capital are reaping the rewards. Top of list? Cleaner air. A lot cleaner." momentummag.com/paris-proves...

Painting phase of this “poster” is done! #SciArt #LaurierBiology

Systematic reviewers have a 10.7% error rate when screening papers for potential inclusion. In other words, about 1 in 9 abstracts are categorised incorrectly (i.e., false inclusion or false exclusion). This really drives home the benefit of having at least two screeners

Another beautiful study by the lab of @andyshihlab.bsky.social published today in @natureportfolio.nature.com 👏🏻👏🏻👏🏻 #cerebrovascular #aging

Microscopy most especially. To be the first human to ever lay eyes on something. What a feeling.

Carney is planing 15% budget cuts across most of government. @supportourscience.bsky.social and @u15ca.bsky.social worry what that would do to a research system that is already lagging behind other countries. My story for @science.org 🧪 www.science.org/content/arti...

In their Opinion article, Samantha Webster @llssam.bsky.social, Remi Brynn and Kate Poole @katepoole.bsky.social consider how perspectives from both cell biologists and biophysicists will be crucial for characterising mechanosensitive ion channels in vivo. journals.biologists.com/jcs/article/...

📰Latest from our lab (Open Access)! Brain Capillary Ion Channels: Physiology and Channelopathies This review attempts to concisely cover a fast-evolving research field on channels in🧠capillaries @apspublications.bsky.social journals.physiology.org/doi/abs/10.1...

Mast cells regulate the brain-dura interface and CSF dynamics @cellpress.bsky.social www.cell.com/cell/fulltex...

Finally published: “Top-down and bottom-up neuroscience: overcoming the clash of research cultures” www.nature.com/articles/s41... Looking for ways to better understand different neuroscientific perspectives and enable productive collaborations

Really useful & inspiring article from @labliston.bsky.social on building a positive and empowering research culture in the lab. Particularly liked the section about making others feel included - such an important aspect for meaningful leadership. wellcomeopenresearch.org/articles/9-3...

Absolutely thrilled to share the first half of my PhD work! Super proud to see it finally out! www.nature.com/articles/s41... Thread below for a quick (10 point) recap of what we found! 🧵🧪🧠

Dear all, PLEASE add comments on the importance of model organism research at this link:

Great new paper out of Jian Wang’s lab! Great to see transcriptomic assessment of intact contralateral tissue relative to uninjured controls, vs. using it as an internal control to the injured hemisphere. Expression changes in distal regions matter! Also- very nice comparison of ICH models here.

Central nervous system injury-induced chronic pain affects millions of people. A delayed-onset pain-like response is observed following selective corticospinal lesions. Xiaofei identified a key role for corticospinal control of deep dorsal horn interneurons in pain. www.jneurosci.org/content/earl...

Does everyone know there is a comment period re: changes in animal research at NIH? I didn't. Closes July 14. The scientific community need to respond en masse. I asked university leadership to distribute to reach our colleagues not on social media, you can too go.pardot.com/e/858023/duc...

We are excited to report: Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IP3R2-mediated Ca2+ signaling in mice Vittani et al. PNAS (2025) pnas.org/doi/10.1073/...

A Review on changing genes, cells and networks to reprogram the brain after stroke www.nature.com/articles/s41...

Not my paper, but a must-read for brain fluid nerds 🧠💧 Awesome new review on how CSF and ISF dynamics shift after ischemic stroke: fluidsbarrierscns.biomedcentral.com/articles/10....

Having an APOε4 allele may be risk factor for brain hemorrhage with apixiban, a commonly used blood thinner for atrial fibrillation jamanetwork.com/journals/jam...

Just spent half of today working on a career goals statement for a fellowship application only to realize that the max length was 2500 characters, not 2500 words 🙃 …Back to the drawing board.

Exploring Iron Deposition Patterns Using Light and Electron Microscopy in the Mouse Brain Across Aging and Alzheimer's Disease Pathology Conditions onlinelibrary.wiley.com/doi/10.1111/...

🚨 We’re looking for a curious mind to join our lab at the NIH! Passionate about #RNA biology, #MachineLearning, and the #genomics of #aging? Interested in a postdoc or a PhD research visit at NIH? Let’s connect. 📩 DM or email for details! #Bioinformatics #AI #ComputationalBiology

Identification of the velum interpositum as a meningeal-CNS route for myeloid cell trafficking into the brain: @cp-neuron.bsky.social www.cell.com/neuron/fullt...

An apocrine secretion mechanism in the choroid plexus that modulates the CSF protein composition and instructs cortical development @lehtinenlab.bsky.social www.nature.com/articles/s41...

Read our latest review article out in @thelancetneuro.bsky.social if you want to know more about CSF transport across the different compartments of the brain-meningeal border and its importance for neurological diseases with strong neuroimmune components 😉 authors.elsevier.com/a/1l7l75FFzL...