🚨 Our search for a postdoctoral researcher is still on! Contact me if you feel passionate about investigating neuroimmune mechanisms in neurodegenerative disorders. Candidates should have proven experience with rodent models of neurodegenerative disorders.

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Do sex diff shape white matter vulnerability in autosomal dominant Alzheimer’s disease? Our new paper in Brain Communications suggests they do, revealing sex-specific patterns of microstructural alterations linked to pathology and structure-function coupling. Check it out! doi.org/10.1093/brai...

Brain-engrafted monocyte-derived macrophages from blood and skull-bone marrow exhibit distinct properties - Neuron @cellpress.bsky.social www.sciencedirect.com/science/arti...

Scary…

🚨 PhD Programme – Vascular Dementia Research New 4-year PhD funded by BHF & UK DRI on vascular mechanisms in dementia. Training across UCL, Oxford, Leicester & Edinburgh with lab rotations. 📅 Deadline: 14 April 🎓 Start: Sept 2026 Apply: CV + statement + 2 refs → [email protected] Please share!

OBS Neuroimmunology Webinar — Monthly on the 3rd Thu, 12 PM ET Skull bone channels regulate immune infiltration @eemescolan.bsky.social (Center for Immunology of Marseille-Luminy) MR1/MAIT cell axis in 5XFAD mice @seasonjohnson.bsky.social (Indiana Univ) *Zoom: us02web.zoom.us/meeting/regi...

Excited to share our new study using engineered immune proteins to quench inflammation in aged brains!! Congratulations to Paloma Navarro and the entire team! Fantastic collaboration with Chris Garcia's lab, Tony Wyss-Coray's lab, and Saul Villeda's lab! www.cell.com/immunity/ful...

#WeekendRead! #EveryCellIsAnImmuneCell! Vollmers Turley &co show @natimmunol.nature.com that lack of CSF1 in skin #fibroblasts decreases macrophage numbers dampening wound repair, and in turn boosts fibroblasts! In human #scleroderma the cellular circuit between fibroblasts & macrophages is altered!

Brain-wide mapping of oligodendrocyte organization, oligodendrogenesis, and myelin injury: Cell www.cell.com/cell/fulltex...

What accounts for the progression from healthy aging to Alzheimer's disease over an extended period of time? The critical role of the immune system, particularly T cells and microglia. A new, excellent review www.cell.com/immunity/abs...

Registrations and abstract submissions for #AstrocyteCafe2026 are now OPEN!!! Spread the word 🤩 We hope to see many of you on June 3-5 in Pamplona!!! Thanks Kernel Science, for our brand new website and for helping organize this conference! 👇👇👇👇 astrocytecafe.com#/conference-...

The Da Mesquita lab at Mayo Clinic (www.mayo.edu/research/lab...) is looking for a postdoctoral researcher to work on projects investigating the role(s) of the meningeal lymphatic vasculature in models of neurodegenerative diseases. Please spread the word and contact me in case you are interested! 😃

Go SCOTUS! it’s been a while since they got one right…

Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease | PNAS www.pnas.org/doi/10.1073/...

Lu lab shows tumor-derived cystatin-C attenuates AD amyloid pathology by acting as molecular glue between microglial TREM2 & amyloid oligomers. This study links cancer biology & AD, spotlighting therapies aimed at clearing existing amyloid plaques www.cell.com/cell/fulltex...

Predicting when symptoms of Alzheimer's disease will occur with a single elevated p-tau217 blood test and a person's age, even 20+ years in advance @naturemedicine.bsky.social nature.com/articles/s41...

Liver exerkine reverses aging- and Alzheimer’s-related memory loss via vasculature: Cell www.cell.com/cell/fulltex...

Sleep-dependent clearance of brain lipids by peripheral blood cells www.nature.com/articles/s41...

🚨We're hiring a new editor!🚨 We're especially looking for someone with expertise in neurodegeneration and cellular/molecular neuroscience. Must have a Ph.D. and be able to work from Madrid, Shanghai, or Pune. Deadline to apply is March 9. springernature.wd3.myworkdayjobs.com/SpringerNatu...

How does inflammation kill neurons, and what can we do about it? Check out our latest paper where we consider this question: rdcu.be/e4nfP.

The Da Mesquita lab at Mayo Clinic (www.mayo.edu/research/lab...) is looking for a postdoctoral researcher to work on projects investigating the role(s) of the meningeal lymphatic vasculature in models of neurodegenerative diseases. Please spread the word and contact me in case you are interested! 😃

PIP2 corrects an endothelial Piezo1 channelopathy | PNAS www.pnas.org/doi/10.1073/...

Excessive #inflammation? We uncover @cp-immunity.bsky.social that #IFN-I via #ISG15 in macrophages lowers #mitochondrial membrane potential, boosts #efferocytosis, and self limits #ISG amplification: a built in brake that promotes resolution. Open-access: www.cell.com/immunity/ful... #immunosky

Can confirm

Today’s CBO report says US consumers pay 95% of tariffs. 🤡 @brendanvduke.bsky.social www.cbo.gov/system/files...

Targeting lymphatic vessels enhances bone regeneration by augmenting osteoclast activity in mouse models of amputation

Overjoyed to share our new work exploring the antigen specificity of CSF-expanded CD8+ T cells in #multiplesclerosis #EBV in @natimmunol.nature.com #immunology 🧪🧵1/ www.nature.com/articles/s41...

Meningeal blood vessel blockage enhances anti-glioblastoma immunity www.cell.com/cell/fulltex...

Can tell how bad it is from 1st sentence: “While peer review is an essential part of funding meritorious scientific research, it is also important to consider other factors…”

Meningeal B cells: Emerging players at the brain border: Immunity www.cell.com/immunity/abs...

@science.org is looking for a new research editor to handle papers in the field of next-generation #medicine! Spread the word!!! bit.ly/4bWOJfn

@jengommerman.bsky.social lab reveals that dynamic changes in the brain, leptomeninges, & dural B cells are associated w/ age-dependent disease severity in an animal model of progressive #MultipleSclerosis rupress.org/jem/article/... 📘 #Immunology Update Winter 2026 👉 rupress.org/jem/collecti...

Very cool work on T cell responses in the human meninges of neurodegenerative disease patients from the group of our soon-to-be Mayo Clinic colleagues Betsy Bradshaw and Wassim Elyaman. Check it out 👇🏻

The Venkatesh lab is looking for a junior technician to join us this summer. If you are interested in working in cancer neuroscience, check out the job description below and see if it is a good fit for your goals! www.linkedin.com/jobs/view/43...

A #Dartmouth study in Nature Communications reveals that immune cells in the brain use a surprising two-step process to power their search-and-destroy missions: the brain’s emergency responders arrive powered by sugar, then build roads to recruit reinforcements for longer-term damage control.

Please see our jobs page for new roles we are hiring for (including postdoctoral researchers, scientists interested in functional genomics and machine learning, and a bioinformatics engineer): arcinstitute.org/jobs

Plasma extracellular vesicles from APOE3 Christchurch carriers display a protective phenotype in early stages of autosomal dominant Alzheimer's disease alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

precisely this OMB’s push for multi-year funding (MYF) is an accounting fiction designed to kill the most promising and novel science in its infancy

Trump has been in office for one year. We at @nature.com did a deep dive looking at the administration's disruption of science in numbers. Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social

NIH budget bill out today. It’s the result of heavy negotiations in Congress over past month+. 🧪 Big pic: NIH budget now is abt more than funding. It’s abt restraining the technical ways NIH is being broken by Proj 2025. And the restraints in the bill are tepid 🤷‍♂️ Also: watch ICE/DHS budget. 🧵1/

Seeing my mentees thrive brings me, by far, much more joy than personal success! Huge congrats on your F31 NOA, Lupe!!! Let it be the first of many more achievements in 2026! 🎉🎊🍾 @sanchezlulu.bsky.social

3 papers in Cell @cellpress.bsky.social today exploring the mechanistic connection between Epstein-Barr virus and multiple sclerosis #MultipleSclerosis cell.com/cell/fulltex... cell.com/cell/fulltex... www.cell.com/cell/fulltex...

Depletion of Microglia Increases Cortical Oligodendrocyte Density During Remyelination onlinelibrary.wiley.com/doi/10.1002/...