@lehtinenlab.bsky.social
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New BioRxiv Post‼️ A Multi-Modal atlas combining human pathology, mouse modeling, transcriptomics, and advanced imaging. Check out the pre-print here:
www.biorxiv.org/content/10.6...
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Multi-modal choroid plexus pathology in aging and Alzheimer’s disease
Brain barriers, cerebrospinal fluid (CSF) dynamics, and peripheral factors are implicated as significant contributors to Alzheimer’s disease (AD). The choroid plexus (ChP) is a blood-brain interface t...
https://www.biorxiv.org/content/10.64898/2025.12.30.697051v1
about 1 month ago
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Led by
@scienceyael.bsky.social
& out today in
@natneuro.nature.com
: the brain's fluid-secreting organ — the choroid plexus — can reshape neural development through a powerful, little-known process. & it can be hijacked by serotonergic drugs like LSD. 🧠👇 A thread
rdcu.be/eoaSY
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Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development
Nature Neuroscience - The choroid plexus (ChP) provides molecular cues for brain development. However, the underlying mechanisms are unclear. This study identifies an apocrine secretion mechanism...
https://rdcu.be/eoaSY
9 months ago
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