No Genetics? Try ASOs – A non-genetic approach to silence genes at the phage-host interface. We use it to study jumbo phage biology and anti-phage defence. @jorg-vogel-lab.bsky.social @helmholtz-hiri.bsky.social @uni-wuerzburg.de @helmholtzhzi.bsky.social published now in @nature.com

Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…

🚀 New publication alert! 🚀 We just published in @natbiotech.nature.com: 👉 Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes doi.org/10.1038/s415...

Excited to share our new preprint co-led by @jnoms.bsky.social! Here we reveal an exceptional diversity of viral 2H phosphodiesterases (PDEs) that enable immune evasion by selectively degrading oligonucleotide-based messengers. This 2H PDE fold has evolved striking substrate breath & specificity.

🚀 Today we're launching the 'Night Science Institute', a non-for-profit organization to lead a cultural shift in science! You may say we're dreamers 😉, but we think we're not the only ones. Perhaps today you will join us to make the Day Science and Night Science parts of the process live as one!

I am super excited to announce that I will be starting my lab at the Department of Pharmacology of the University of Zurich in Switzerland next year!

A new preprint led by Sonomi Yamaguchi in our lab describes a bacterial anti-phage defense system named Clover that uses nucleotide signals to both activate and inhibit host immunity. www.biorxiv.org/content/10.1...

We have written up a tutorial on how to run BindCraft, how to prepare your input PDB, how to select hotspots, and various other tips and tricks to get the most out of binder design! github.com/martinpacesa...

'Structural insights into Cas9-mediated prespacer selection in CRISPR-Cas adaptation' Check out our preprint on #bioRxiv on the #Cas9-Cas1-Cas2-Csn2 supercomplex involved in #CRISPR spacer acquisition: www.biorxiv.org/cgi/content/... Thread below.

PhDs, Postdocs and young PIs listen up! Next to connecting young scientists, we organised an engaging Night Science 💫 workshop (by @itaiyanai.bsky.social and Martin Lercher), and an epic social event at one of Vilnius’ best venues 🍻 .

This year's EMBO Young Scientists’ Forum (EYSF) will take place in Vilnius, LT from 24–26 Sep 2025. The EYSF brings together scientists across #Europe for #networking and scientific exchange – Apply now! 🧪 Abstract submission by 1 Aug Registration by 15 Aug meetings.embo.org/event/25-eysf

I'm looking for a postdoc in computational evolutionary phage genomics, with the goal to better understand how protein innovation arises in viruses, at @jagiellonskiuni.bsky.social in Krakow (Poland). Drop me a line if it sounds cool! Deadline: 20.06. Link here: mcb.uj.edu.pl/documents/15...

We are very excited about our latest work, which just came out @embojournal.org – www.embopress.org/doi/full/10..... The work @MCB_UJ was driven by Anna Biela and Ting-Yu Lin 林亭妤 in collaboration with @jmbujnicki.bsky.social…a short🧵

And here it is, the completed BASEL collection finally published as early access in @plosbiology.org - see the thread for more details. 🤗🧬🎣

Please spread the word! We have an opening in the Atkinson lab for a post-doc with a focus on the molecular mechanisms of microbial immune systems. Can be a fully computational or experimental or hybrid project. Read more and apply here: lu.varbi.com/en/what:job/... #phage #bioinformatics

Science is an investment that pays enormous dividends. So if you’re business-minded, it’s an offer you can’t refuse! Here's my full speech from the Stand Up For Science rally in DC today: www.youtube.com/watch?v=eemj...

Dive into our lab’s first peer-reviewed publication—co-led with our friends @benadler.bsky.social and Muntathar Al-Shimary from the @doudna lab! If you’ve already read the preprint, don’t miss the new updates: doi.org/10.1038/s415... @naturemicrobiol.bsky.social

Friends: Science is under threat! Worldwide, forces seek to make it corporate-like, focused on deliverables, or even the enemy of society. It's time to take a stand to celebrate the science we know and love. Introducing: Woodstock.Bio2 + Night Science June 10-13, Prague & Woods of Bohemia Join us!

🚨 🧬 Updated preprint on the completed BASEL collection - what's new? Some fun with bacterial immunity and a new P22 relative infecting E. coli K-12. A thread 🧵