A single-cell cytokine dictionary of human peripheral blood: 9.7M cells, 12 donors, 90 cytokines www.biorxiv.org/content/10....

From the @geneontology.bsky.social team in the @narjournal.bsky.social #NARDatabaseIssue | The Gene Ontology knowledgebase in 2026 | #Bioinformatics #Database #OpenScience #GO #Ontology #GeneOnlology #OpenData 🧬 🖥️🧪🔓 ⬇️ academic.oup.com/nar/advance-...

See 👇 our new manuscript introducing SpaCEy, an explainable method for predicting clinical outcomes from spatial omics data 🧬 📄 Paper: www.biorxiv.org/content/10.6... 💻 Code repo: github.com/saezlab/SpaCEy

1/ We are excited to announce Parathaa: a new method for improving taxonomic classification of amplicon sequencing data. Parathaa aims to directly model sequence ambiguity to identify amplicons to the finest taxonomic level possible. academic.oup.com/nar/article/...

As the year ends, we decided to select our favorite papers of 2025 Turns out, it is impossible as we love them all! So, we picked 'some' that exhibit the range of microbiology highlighted through the columns of Nature Microbiology. Here is a glimpse into #EditorPicks of 2025 #MicroSky 🦠

Grateful to share our paper on gene-specific selective sweeps in human gut microbiomes, now out in Nature! It has been a joy to work with @rwolff.bsky.social, whose insights and hard work made this possible. www.nature.com/articles/s41...

👋@sbmeubc.bsky.social and @bccancerfdn.bsky.social are seeking a successful candidate for the Dr. Connie Eaves Chair in Cancer Stem Cell Research (Professor or Associate Professor with tenure). Please apply if you have innovative engineering solutions and technologies! www.nature.com/naturecareer...

Tier 2 Canada Research Chair in Cancer Biotherapeutics @westernu.ca London Canada! Join our world-class cancer research initiative developing novel therapies that transform patient outcomes. @schulichmeddent.bsky.social www.uwo.ca/facultyrelat... #AcademicJobs #AcademicSky #AcademicChatter

Nature Reviews Genetics Focus issue: Eco-evolutionary genomics of microorganisms www.nature.com/collections/... 🧬🖥️🧪🦠 🧵 1/

#JobAlert - Canada Research Chair (CRC) – Tier 1 Chair in Metabolomics for Novel Therapeutics at the Schulich School of Medicine & Dentistry at the University of Western Ontario. Info here: csmb-scbm.ca/canada-resea...

2 new studies that show how fasting/caloricrestriction can help vs breast cancer in the experimental model www.nature.com/articles/s42... www.nature.com/articles/s41...

👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen rdcu.be/eT1Su

Tolerance to the antifungal drug fluconazole is mediated by tuning cytoplasmic fluidity https://www.biorxiv.org/content/10.64898/2025.12.03.691994v1

“To make this discovery accessible, the researchers developed EVMap, a free, interactive online resource that lets scientists worldwide explore the molecular makeup of blood EVs“ #ExtracellularVesicles #Blood #Science #Scicomm phys.org/news/2025-11...

This is fascinating “Furthermore, these findings raise questions about whether anti-PD-1 blockade during cancer immunotherapy provides a short-term anti-tumour effect at the cost of diminishing efficacy due to progressive loss of these critical high-affinity precursors.” #Immunology

Happy to see this work finally published in Microbiome! link.springer.com/article/10.1...

The Canadian Bioinformatics Hub is accepting applications for their recognition awards. Three awards are available: CBH Research & Innovation Award, Francis Ouellette Community Award, and CBH Impact Trainee Award. Apply by Dec 8, 2025: www.iscb.org/cbhc2026/cal...

🚀 Ready to lead the next frontier of AI in health care and research? UHN is hiring a Coordinator to spearhead the Blue Vest #AI Initiative at @PMResearch_UHN @PM_CDI to train student volunteers and empower clinicians & scientists. 📍 Toronto 🔗 Apply: smrtr.io/vC7zh

The Canadian Bioinformatics Hub Training Award application deadline is coming up soon on Dec 1, 2025! Successful applicants will receive up to $2,500 CAD to attend a workshop, tutoral, or other training event in 2026. Learn more and apply: bioinformatics.ca/hub/training...

I'm happy to share a perspective that @soniamodilevsky.bsky.social and I wrote about a new and exciting paper in @science.org with big implications for IBD. Check it out: A bacterial toxin disarms gut defenses against inflammation | Science www.science.org/doi/10.1126/...

Our new paper is out in Nature - online today! Huge congrats to shared first authors Sofía Ibáñez-Molero & Johanna Veldman, the whole team & all collaborators. 📄 Open-access paper: www.nature.com/articles/s41...

Akkermansia muciniphila has potential as a next-generation #probiotic, but can it claim a niche and persist in a pre-existing, complex microbial community (in vitro)? 🦠🔍 #microsky #microbiomesky #glycotime link.springer.com/article/10.1...

Tier 2 Canada Research Chair in Cancer Biotherapeutics @westernu.ca London Canada! Join our world-class cancer research initiative developing novel therapies that transform patient outcomes. @schulichmeddent.bsky.social www.uwo.ca/facultyrelat... #AcademicJobs #AcademicSky #AcademicChatter

MIT book Introduction to Machine Learning Systems by Vijay Janapa Reddi: • PDF www.mlsysbook.ai/assets/downl... • EPUB www.mlsysbook.ai Data Engineering Model Development Optimization Deployment Infrastructure Monitoring Security, Privacy, Safety Scaling Responsible AI Future

The AIRR-ML-2025 challenge is LIVE on @kaggle.com! We’re challenging the best in #MachineLearning & #DataScience to decode the immune system. 💰 $10,000 prize pool 📄 Co-author a NatureMethods paper

Very excited to share our latest work in Science on metagenomic editing (MetaEdit) of the gut microbiome in vivo & directly modifying unculturable immune-modulatory SFB bug in the small intestine. 🦠🧬🛠️ www.science.org/doi/10.1126/...

We wrote the Strain on scientific publishing to highlight the problems of time & trust. With a fantastic group of co-authors, we present The Drain of Scientific Publishing: a 🧵 1/n Drain: arxiv.org/abs/2511.04820 Strain: direct.mit.edu/qss/article/... Oligopoly: direct.mit.edu/qss/article/...

Come join us @westernu.ca @schulichmeddent.bsky.social as Canada Research Chair (CRC) Tier 2 in Cancer Biotherapeutics: uwo.ca/facultyrelat... DM me with questions. As a CRC 2 recruit to ACB, I highly recommend it!

Introducing Cancer Trials Canada - a new website to make it easier than ever to find cancer clinical trials happening across Canada. Clinical trials test new ways to prevent, detect and treat cancer. They help advance research that can lead to better care and save lives.

#NewResearch Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes @rstepanauskas.bsky.social & co #microsky www.nature.com/articles/s41...

How do GWAS and rare variant burden tests rank gene signals? In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck! 🧬🧪🧵 www.nature.com/articles/s41...

Great to see this finally published! Metalog: curated and harmonised contextual data for global metagenomics samples now out in @narjournal.bsky.social academic.oup.com/nar/advance-...

very cool paper: t.co/mxObUMC8R4 Cancer cells can transfer their mitochondria to T-cells which impairs the immune response t.co/dkEv5L5Bb0

Our @narjournal.bsky.social manuscript is out! It explores the growth of the GTDB (gtdb.ecogenomic.org) since its inception, as well as updates to the website, methodology, policies, and major taxonomic and nomenclatural changes over the past three years. academic.oup.com/nar/advance-...

Systematic benchmarking of high-throughput subcellular spatial transcriptomics platforms across human tumors www.nature.com/articles/s4...

We’ve entered a new era in health care, driven by collaboration across disciplines and powerful tools like artificial intelligence and big data. Your support will accelerate breakthroughs and improve patient care. #AllinWesternU Learn more: allin.westernu.ca/optimizing-h...

#Candida albicans is a leading opportunistic fungal #pathogen of humans. Ci Fu, Leah Cowen &co expand the GRACE #Calbicans #FunctionalGenomics resource, identifying genes important for temperature-dependent fitness & highlighting its power to reveal vulnerabilities @plosbiology.org 🧪 plos.io/3Wft0Xg

Congrats to Yancong, Amrisha, Xochitl, Eric and all co-authors!!!

MrVI, based on deep generative modeling, is a unified framework for integrative, exploratory, and comparative analyses of large-scale (multi-sample) single-cell RNA-seq datasets. @justjhong.bsky.social @canergen.bsky.social @elhamazizi.bsky.social www.nature.com/articles/s41...

Want to be our colleague? We have a faculty position in microbial systems biology looking for candidates. Please share. www.rh.ulaval.ca/emplois-disp...

We’re launching a major #recruitment call for staff scientists in #ComputationalBiology, #DataScience, and #AI to strengthen Sweden’s life science research. 🧪🖥️ Positions are based at SciLifeLab sites across Sweden’s leading universities. Learn more and apply ↓ www.scilifelab.se/news/scilife...

Microbiology & Immunology at Western University is hiring a tenure-track Assistant Professor in the area of Neurovirology. Read the description here: www.uwo.ca/facultyrelat...

Microbiology & Immunology at Western University is hiring a tenure-track Assistant Professor in the area of T cell Biology and Neuroimmunology - one of two positions available. Full description here: www.uwo.ca/facultyrelat...

We are looking for a postdoc to study single-cell transcriptional heterogeneity in the human skin microbiome. We have a new protocol mostly developed, but need someone to see it through. Experience with protocol dev or RNAseq appreciated. Funded by a new grant from MIT-HEALS.

Scvi-hub is a versatile and efficient platform for model-based analysis of single-cell sequencing studies with access to a diverse array of datasets and downstream analysis. @canergen.bsky.social www.nature.com/articles/s41...

High costs motivate efforts to predict spatial transcriptomics from H&E images w/ deep learning. In our recent preprint, we show that noise, sparsity & resolution in ST data impact performance, highlighting the importance of training data quality: www.biorxiv.org/content/10.1... 🧵1/n

Now is the time to sign up for the Run for the Cure! From now until 11:59 p.m. PST on September 10, 2025, all donations in support of the #CIBCRunForTheCure will be matched by CIBC, dollar for dollar, up to $500,000.

Conditional generation of real antigen-specific T cell receptor sequences @natmachintell.nature.com www.nature.com/articles/s42...

Tomorrow begins #GloMiNe2025 organized by @microbiotavault.bsky.social & #MVIF Atlantic session will be open by Gloria Dominguez-Bello & @cpavloud.bsky.social Pacific session by Safarina Malik & Célio Dias Santos Júnior Both sessions will be LIVE! Check the details: cassyni.com/s/mvif-glomi...