Unlocking secrets of #meiosis! Wei et al. reveal how Mei5-Sae3 complex enhances Dmc1p assembly by stabilizing Dmc1p clusters on ssDNA, altering RPA dynamics, paving way for successful interhomolog recombination. Fascinating proteins in action! #yeast #Genetics www.yeastgenome.org/reference/39...

Insights into mitochondrial #ribosome reveal mL44 mutations linked to childhood #cardiomyopathy, neuro issues. Box et al. study #yeast homolog MRPL3, show evolutionary divergence, translation hierarchy in mitochondrial protein synthesis #Mitochondria #Genetics www.yeastgenome.org/reference/38...

Cap-binding protein eIF4E links protein synthesis to metabolic regulation. When depleted, cells adapt by upregulating amino acid catabolism and biosynthesis. Read how this regulation helps maintain balance during stress. #CellBiology #ProteinSynthesis #yeast www.yeastgenome.org/reference/38...

2026 #Yeast #Genetics Meeting is 13–17 June 2026 in Pacific Grove CA. Conference website has invited speakers, abstract submission topics, preliminary schedule, etc. Bookmark the site as additional updates will be published as they become available. #YEAST26 genetics-gsa.org/yeast-2026/

The 33rd Fungal Genetics Conference is accepting abstracts - due December 4, 2025! genetics-gsa.org/fungal-2026/... #FUNGAL26

📣Advance your skills in #pathogen genomics — no coding required — with the #Fungal Pathogen Genomics (Virtual) course #FungiDB @ensembl.org #mycocsm @yeastgenome.bsky.social #CGD 🗓️ 1–5 June 2026 Deadline: 16 March 2026 Apply here: coursesandconferences.wellcomeconnectingscience.org/event/fungal...

Abstract submission and registration now open for the 33rd #Fungal #Genetics Conference at #Asilomar! Abstracts due December 4, early registration deadline December 5. genetics-gsa.org/fungal-2026/

Nature has published an article on the crisis facing MODs Model organism databases face budget cuts and closures www.nature.com/articles/d41... @zfinmod.bsky.social @xenbase.bsky.social @yeastgenome.bsky.social @mousegenome.bsky.social @ratgenome.bsky.social @geneontology.bsky.social @nature.com

Utterly devastating: FlyBase zapped. www.thetransmitter.org/community/ha... #modelOrganism

Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited

Latest #yeast #microPublication: Schiemann et al. Functional Analysis of the Yeast Counterpart to the Human GCN2 p.Glu738_Asp739insArgArg Variant www.micropublication.org/journals/bio... @micropub7n.bsky.social

WormBase announces its final major update, WS298, will be in Oct2025. No more new WormBase releases; existing data will be moved into Alliance of Genome Resources, ensuring vital C. elegans datasets remain accessible. Stay tuned for more updates. Read more: blog.wormbase.org/2025/07/23/a...

#YeastNomenclature reminder: Protein Name Format #Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).

On 16 June, a federal court in Boston will hear two cases challenging the terminations of hundreds of National Institutes of Health grants.

FlyBase needs your help! Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org

Noticing slowness on the SGD website? Thank the web-scraping AI bots www.nature.com/articles/d41...

#YeastJob: 2-year postdoc available at #Sorbonne Université (central Paris) to investigate dynamic architecture of natural polyploid genomes in #Saccharomyces cerevisiae focusing on resolving complex genomic structure of polyploids at population level. More info docs.google.com/document/d/1...

Virtual #Conference: 5th Annual CanFunNet #Fungal #Biology August 6-8 "From Local to Global" canfunnet.conferences.uwo.ca Abstract submissions, early registration open until May30 Topics include: Evolutionary Pathways of Fungal Pathogens, Fungal Genomics, Host Interactions, Fungal Resilience

SGD Newsletter is out! www.yeastgenome.org/blog/sgd-new... - SGD’s Latest #GENETICS Publication - #Pathway Annotations Available as GO Annotations - New #Yeast #Phenome Links - #microPublications – Latest Yeast Papers - Alliance of #Genome Resources – Release 8.1.0 - Upcoming Conferences & Courses

There are 220 #BiochemicalPathways in #Yeast, involving 557 different #genes - all this info has now been incorporated into #GeneOntology annotations - check it out! www.yeastgenome.org/blog/yeast-b...

Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out! meetings.cshl.edu/courses.aspx...

#YeastJob: Postdoc in Environmental Micro and Genomics Food Nutrition and Health Program, UBC in Vancouver Wine Research Centre collab w/ Renaissance Bioscience Corp www.renaissancebioscience.com Lab of Dr Vivien Measday measday-lab.landfood.ubc.ca community.alliancegenome.org/t/postdoctor...

The Pacific Northwest Yeast Club is holding their annual meeting on June 20th, 2025 in beautiful Vancouver, Canada! There are only 100 spots and registration is open now: www.pnwyc.net

New SGD paper! Saccharomyces Genome Database: advances in genome annotation, expanded biochemical pathways, and other key enhancements academic.oup.com/genetics/art...

Friendly reminder that community resources like SGD rely on your usage and citation for continued funding. Make sure to follow the citation guidelines and include in-text citations, not just links. #modelOrganism

Apply by March31 for the 2025 Yeast Genetics and Genomics Course Jul22–Aug12 www.yeastgenome.org/blog/apply-n... This year’s instructors –Grant Brown, Soni Lacefield @lacefieldlab.bsky.social, and Greg Lang– have designed a comprehensive course covering all things yeast from genetics to genomics!

Article by Dr. Kurt Williamson, Biology at #William&Mary: "I work with undergraduate students at the very beginning of their professional careers. The loss of training and support of new and early-career scientists is a particularly hard blow that will affect all of us for years to come."

FEBS Workshop 2025 – Conservation and diversity of gene regulatory mechanisms across eukaryotes 16–20 June 2025 │ Sant Feliu de Guixols, Spain Deadlines: Registration closing: 15 March 2025 Abstract submission: 15 March 2025 community.alliancegenome.org/t/febs-2025-...

Join #Ensembl, #FungiDB / @veupathdb.bsky.social, @yeastgenome.bsky.social / #CGD and #MycoCosm / @jgi.doe.gov at this year's Fungal Pathogen Genomics course organised by @eventswcs.bsky.social 🍄🧬💻 Applications close on Tue, 18th March 2025 📆 2nd to 6th June 2025 📍 Virtual ℹ tinyurl.com/fpg2025

From the 52 Biodata resources listed on the GCBR website globalbiodata.org/what-we-do/g... 24 exist in the US, and of those, 12 are NOT mirrored, officially. Of these 52 resources, 29 are supported by the NIH. If Trump/Musk continue, we are FUBARed! #Bioinformatics #Genomics #SciPo 🧬 🖥️ 🧪

YEAST2025: 32nd International Conference on #Yeast #Genetics and Molecular #Biology Sorbonne Université, Paris, France ICYGMB32, July 21-24, 2025 premc.org/yeast2025/

Giving to SGD just got easier! We now accept donations by credit card with this form: give.stanford.edu. Select ‘Other Stanford Designation’ under ‘Direct your gift’ & in the ‘Other’ box, add: Saccharomyces Genome Database-Account:GHJKO, Genetics:WAZC. Thanks for your support!

CSH Asia: Yeast and Life Sciences Suzhou, China June 2-6, 2025 Abstract deadline: March 28, 2025 www.csh-asia.org?content/2721

Yeast Genetics & Genomics at CSHL July 22 - August 12, 2025 Application Deadline: March 31, 2025 Arrival: July 22nd by 6pm EST Departure: August 12th around 12pm EST For more info and to apply please visit the Yeast Genetics & Genomics course website: meetings.cshl.edu/courses.aspx...

If you are using bots to scrape SGD, please stop. You are overloading the database and adversely affecting other users.

Global Biodata Coalition is profiling SGD this week! Click to learn more about SGD's impact on scientific research - bit.ly/3W7XdI9

EXTRA! EXTRA! Read all about it! Latest SGD newsletter! www.yeastgenome.org/blog/sgd-new... - AlphaFold - YeastMine - Community wiki - SGD’s new GENETICS publication - New yeast microPublications - Alliance of Genome Resources 7.4 - Give a Gift/Support SGD - Upcoming conferences - Happy Holidays!

Announcing microBREW 2025: a free online webinar on assessment of undergraduate experiential learning in biology labs! We are seeking abstracts for lightning talks; more information on registration soon. Info and abstract submission on our website: brewmor.org/microbrew-20...

The Global Biodata Coalition has an open letter campaign to show support for sustainable funding for biodata resources. Please take a minute to read and sign globalbiodata.org/open-letter-...

Global biodata resources are at risk - funding models are fragile and unsustainable. GBC's open letter campaign needs your support to call for solutions. Science leaders have already signed the letter, please join them. Click here for more: globalbiodata.org/open-letter-...

AlphaFold protein structures now on SGD protein pages, now you can explore these comprehensive structural predictions directly within SGD for your favorite #yeast proteins check it out: www.yeastgenome.org/locus/set1/p...

❓ GO puts the FUN in function, yes - but what is phenomenal for phenomics??? ➡️ uPheno! Read more about the fantastic Unified Phenotype Ontology here: community.alliancegenome.org/t/ever-neede...

Due to ongoing funding cuts, SGD is trimming unused services. Next up is the SGD Community Wiki: wiki.yeastgenome.org/index.php/Ma.... We will move some of the pages to the SGD Help site: sites.google.com/view/yeastge... Donations are now critical for us to continue. More info: www.yeastgenome.org

Do you use GO GPAD files? Although mostly used for internal purposes, if you use GPAD files please be aware the format is getting an update to GPAD 2.0 and this is a breaking change. Details at community.alliancegenome.org/t/go-file-fo...

Ever see a #GeneOntology annotation that doesn't use a PMID as a reference, but instead has GO_REF: and a bunch of numbers? Find out what a GO_REF is & where to find full descriptions of them in this week's Alliance Forums post: community.alliancegenome.org/t/whats-a-go...

SGD distributes data via the SGD Downloads site: sgd-archive.yeastgenome.org For info regarding genes see the Chromosomal_features directory. For annotations, see the Literature directory. To access SGD Downloads, click on ‘Download’ in the black toolbar running across the top of SGD webpages.

YeastMine shutting down July 15: Due to ongoing cuts to our funding, SGD can no longer continue to provide the YeastMine data warehouse resource. It is with heavy hearts that we discontinue this service. community.alliancegenome.org/t/yeastmine-... #yeast

#Yeast as #art! www.yeastart.org/super-yeast

#Yeast Reference #Genome Annotation Update R64.5: *new ORFs: YDL204W-A, YFR035W-A, YGR016C-A, YMR106W-A, YNL040C-A, YNL155C-A *new uORFs for existing ORFs: ATG12, ATG19, ATG5, ATG13 *move start downstream: EFM4 *ORF upgraded from Dubious to Verified: YIL059C www.yeastgenome.org/blog/referen...

Give a Gift / Support SGD! Budget reductions and inflation continue to strain SGD's finances. Despite our efforts, we continue to have significant budgetary challenges. Donations are now critical for our work to continue.