bioRxiv Cancer Bio
@biorxiv-cancer.bsky.social
📤 3877
📥 0
📝 5429
X-CODE: a dual RNA barcoding system for multi-platform clonal tracking and spatial phenotyping
https://www.biorxiv.org/content/10.64898/2026.02.10.705126v1
about 8 hours ago
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CDK9 pharmacological inhibition with PRT2527 has antitumor activity in marginal zone lymphoma models and can improve the effects of BTK, PI3K, and BCL2 inhibitors
https://www.biorxiv.org/content/10.64898/2026.02.10.705084v1
about 8 hours ago
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Integrated Cytotoxic and Safety Mechanism of IMV-M (TM), a MUC16 x DR5 Bispecific Antibody
https://www.biorxiv.org/content/10.64898/2026.02.10.705083v1
about 8 hours ago
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MAPK ERK5 Is a Novel Regulator of MHC-I in Cancer Cells
https://www.biorxiv.org/content/10.64898/2026.02.10.705047v1
about 12 hours ago
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Diet-induced macrophage-driven inflammation fuels pancreatic plasticity and aggressiveness
https://www.biorxiv.org/content/10.64898/2026.02.10.703309v1
about 14 hours ago
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Oxidative Stress-Induced Immunogenic Cell Death Enhances Whole-Cell Vaccine Efficacy in a Syngeneic Pancreatic Cancer Model
https://www.biorxiv.org/content/10.64898/2026.02.09.704828v1
about 17 hours ago
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NRF2 co-opts the SWI/SNF complex to drive liver cell plasticity
https://www.biorxiv.org/content/10.64898/2026.02.09.704724v1
about 17 hours ago
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Network-based integration of gene expression and DNA methylation identifies prognostic biomarkers for early-stage pancreatic cancer
https://www.biorxiv.org/content/10.64898/2026.02.09.704985v1
about 17 hours ago
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CAR-T Targeting of Mutant Calreticulin Establishes a Potentially Curative Stem Cell-Directed Therapy for Myeloproliferative Neoplasms
https://www.biorxiv.org/content/10.64898/2026.02.09.704856v1
about 17 hours ago
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Nerve Injury-Induced Protein 2 Is Necessary for the Lysosome Membrane Integrity and Protects Cells from Ferroptosis
https://www.biorxiv.org/content/10.64898/2026.02.09.704867v1
about 18 hours ago
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Obesity and Tumor Development Reprogram the Proteome and Metabolic Effects of Adipose- and Tumor-Derived Extracellular Vesicles
https://www.biorxiv.org/content/10.64898/2026.02.08.704727v1
1 day ago
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RaDRI: A computational model for radiosensitisation by DNA double strand break repair inhibitors
https://www.biorxiv.org/content/10.64898/2026.02.08.704735v1
1 day ago
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Lineage-restricted dependency on an oncofetal SNHG29-IGF2BP1 RNA axis in acute megakaryoblastic leukemia
https://www.biorxiv.org/content/10.64898/2026.02.07.704501v1
2 days ago
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Targeting one-carbon metabolic vulnerabilities of metastasis with therapeutic potential
https://www.biorxiv.org/content/10.64898/2026.02.07.704548v1
2 days ago
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Membrane-coupled conformational switching of VISTA regulates immune checkpoint signaling via CC' loop accessibility
https://www.biorxiv.org/content/10.64898/2026.02.07.704574v1
2 days ago
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Systemic hypoxia suppresses solid tumor growth
https://www.biorxiv.org/content/10.64898/2026.02.09.704975v1
2 days ago
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Targeting Myc activates a tissue-specific tumour resolution programme
https://www.biorxiv.org/content/10.64898/2026.02.06.704498v1
3 days ago
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The DNA damaging properties of the experimental G-quadruplex (G4) drug QN-302 are potentiated by the DNA repair inhibitor Olaparib and mitigated by the molecular helicase PhpC
https://www.biorxiv.org/content/10.64898/2026.02.06.704351v1
3 days ago
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Evaluation and application of chemical decrosslinking in the context of histopathological spatial proteomics
https://www.biorxiv.org/content/10.64898/2026.02.06.704439v1
3 days ago
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Morphospatial profiling of cancer-associated fibroblasts reveals architectural subtypes of pancreatic ductal adenocarcinoma
https://www.biorxiv.org/content/10.64898/2026.02.06.704414v1
3 days ago
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Ex vivo drug testing in metastatic biopsies reveals patient-specific vulnerabilities to cancer targeting and immune activating drugs
https://www.biorxiv.org/content/10.64898/2026.02.06.704037v1
3 days ago
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Reconstruction of epithelial transcriptional trajectories reveals heterogeneous progression and early therapy-resistance programs in high-grade serous carcinomaprecursors
https://www.biorxiv.org/content/10.64898/2026.02.06.704093v1
3 days ago
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In situ vaccine effect of radiotherapy is associated with intratumoural ERV reactivation and RNA virus sensing
https://www.biorxiv.org/content/10.64898/2026.02.06.704391v1
3 days ago
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A genome-wide CRISPR screen reveals cancer-specific regulators of hyaluronan binding and cellular invasion
https://www.biorxiv.org/content/10.64898/2026.02.06.704476v1
3 days ago
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1
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BAP1 Loss Induces Senescence and Enhances the Response to Radiation Therapy and Senolytics
https://www.biorxiv.org/content/10.64898/2026.02.05.704104v1
3 days ago
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A macrophage-derived noncanonical WNT niche drives immune exclusion in pancreatic cancer
https://www.biorxiv.org/content/10.64898/2026.02.05.704114v1
3 days ago
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Pharmacological induction of mitochondrial stress counteracts therapy resistance in glioblastoma stem-like cells
https://www.biorxiv.org/content/10.64898/2026.02.05.704021v1
3 days ago
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The ITCC-P4 PDX platform of pediatric cancers for preclinical testing
https://www.biorxiv.org/content/10.64898/2026.02.04.703023v1
3 days ago
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Proteomics and single-cell transcriptomics identify LRP1 as a diagnostic biomarker for atypical fibroxanthoma and pleomorphic dermal sarcoma.
https://www.biorxiv.org/content/10.64898/2026.02.04.703892v1
3 days ago
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Effects of Spin4 ablation in aging mice: body composition, bone density, and malignancy prevalence
https://www.biorxiv.org/content/10.64898/2026.02.05.704000v1
3 days ago
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Chromatin architecture and physical constriction cooperate in phenotype switching and cancer cell dissemination
https://www.biorxiv.org/content/10.64898/2026.02.05.702638v1
4 days ago
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Recurrent Escape from Osimertinib-Induced Senescence Promotes Genomic Instability Associated with Therapeutic Resistance
https://www.biorxiv.org/content/10.64898/2026.02.07.704600v1
4 days ago
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Accurate somatic variant detection from formalin fixed, paraffin embedded tissue (FFPE) derived WES and WGS by DeepOmicsFFPE-PLUS, a sequence context-based transformer
https://www.biorxiv.org/content/10.64898/2026.02.05.702695v1
4 days ago
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Engineered probiotics for tumor-targeted combination chemoimmunotherapy
https://www.biorxiv.org/content/10.64898/2026.02.04.703875v1
5 days ago
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In situ programming of intratumoural stem cell-like memory CD8+ T cells enables durable antitumour immunity in immunosuppressive tumours
https://www.biorxiv.org/content/10.64898/2026.02.06.700840v1
5 days ago
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Schlafen 11 (SLFN11) overexpression and nucleolar localization in response to bortezomib in multiple myeloma
https://www.biorxiv.org/content/10.64898/2026.02.06.704297v1
5 days ago
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MERTK inhibition cooperates with immunomodulatory cyclophosphamide to induce CXCL9⁺ monocyte-macrophage programming and durable anti-tumor immunity in triple negative breast cancer
https://www.biorxiv.org/content/10.64898/2026.02.04.703648v1
5 days ago
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Photodynamic priming with Vitamin D and ALA-based PDT induces intratumoral immune cell recruitment and signaling pathway activation in murine cutaneous squamous cell carcinoma
https://www.biorxiv.org/content/10.64898/2026.02.04.703788v1
5 days ago
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Aurora kinase A is a synthetic lethal target in FANCA-deficient cancers
https://www.biorxiv.org/content/10.64898/2026.02.04.703705v1
6 days ago
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Data-Driven Mechanistic Computational Modeling of Human Cell Cycle Phases for Defining Inhibitor Combinations in Silico
https://www.biorxiv.org/content/10.64898/2026.02.04.703693v1
6 days ago
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Discrete Transcriptional States Define Biphasic Immune Response and Dynamic CMS Transitions in Colorectal Cancer
https://www.biorxiv.org/content/10.64898/2026.02.03.703597v1
6 days ago
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Multiaxial Biophysical Control of Oncogenic Phase Separation by Indoleamines: A Proof-of-Concept Synthesis of Landscape-Level Regulation
https://www.biorxiv.org/content/10.64898/2026.02.03.703596v1
6 days ago
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Next generation protein-corrole bio-assemblies provide effective tumoricidal treatment in a metastatic triple-negative breast cancer model
https://www.biorxiv.org/content/10.64898/2026.02.03.703292v1
6 days ago
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LIMK Inhibition and Metformin Block Mitochondrial Transfer Overcoming Macrophage Driven Therapy Resistance in Acute Myeloid Leukaemia
https://www.biorxiv.org/content/10.64898/2026.02.03.702377v1
6 days ago
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JAK-STAT Pathway Heterogeneity Governs Immunotherapy Response in Breast Cancer
https://www.biorxiv.org/content/10.64898/2026.02.03.703506v1
7 days ago
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Cellular mechanisms of acquired drug resistance against regorafenib in colon cancer cells.
https://www.biorxiv.org/content/10.64898/2026.02.03.703469v1
7 days ago
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Alkoxylated fisetin derivatives - the new potential drugs against head and neck cancers
https://www.biorxiv.org/content/10.64898/2026.02.03.703451v1
7 days ago
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Mutational signatures in cancer genomes alter protein sequence motifs in cellular signaling networks
https://www.biorxiv.org/content/10.64898/2026.02.03.703397v1
7 days ago
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TERT drives liver tumorigenesis beyond telomere elongation
https://www.biorxiv.org/content/10.64898/2026.02.02.703327v1
7 days ago
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Integrative Multi-Omics Analysis Identifies a Functional Enhancer Driving Tumorigenesis in Head and Neck Squamous Cell Carcinoma
https://www.biorxiv.org/content/10.64898/2026.02.03.703438v1
7 days ago
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