9 more days … #Africa #Bioinformatics #Health #Informatics #Education

“From Data to Discovery: Opportunities with the African Bioinformatics Institute” delivered at the recent Data for Health in Africa Meeting & 5th DS-I Africa Consortium Meeting in Accra, Ghana. Explore ABI’s vision as well current and future activities: www.linkedin.com/pulse/showca...

How do histone mutations contribute to cancer development? Our new study reveals that these mutations impact critical sites where histones interact with DNA or proteins, in some cases disrupting genome maintenance. academic.oup.com/nar/article/...

From #NAR journal | #Cancer #histone mutations impact protein binding and DNA repair with possible links to genomic instability | From my friend @davidlandsman.bsky.social & former colleague @panchenko-lab.bsky.social | #Bioinformatics #Genomics 🧬 🖥️ 🧪 🔓 🇨🇦 ⬇️ academic.oup.com/nar/article/...

Microbiology and Immunology and the Michael Smith Labs are seeking candidates for an Assistant Professor of Teaching in STEM Public Engagement position. Learn more and apply at: www.msl.ubc.ca/careers/ #IndigenousinSTEM #BlackInNature #WomenInSTEM #MinoritiesInSTEM #DiversityInSTEM #STEMEducation

Ezra Klein thinks that “black people are stupid” and “gay people should be stoned to death” is practicing politics the “right way” Can we stop pretending he is some political sage?

My review of computational methods for anthropological genetics with @kwittadna.bsky.social is out for the Yearbook issue of AJBA. We talk about all sorts of cool methods that YOU could use too! Also check out this great figure we commissioned from @janey1216.bsky.social doi.org/10.1002/ajpa...

Stephen Jay Gould was born OTD in 1941. “Organisms are not billiard balls, propelled by simple and measurable external forces to predictable new positions on life's pool table.... Organisms have a history that constrains their future in myriad, subtle ways.” 🦫🦋🐋🌱🧠🗃️🧪#HistSTM #PhilSci #EvoBio

From @cp-patterns.bsky.social | #Bioconductor: Planning a third decade of comprehensive support for genomic data science | #Bioinformatics #Genomics #OpenScience #OpenSource 🧬 🖥️ 🧪 🔓 ⬇️ www.cell.com/patterns/ful...

From @plos.org #Computational #Biology | Catalyzing computational biology research at an academic institute through an interest network | #Bioinformatics #Education #OpenScience 🧬 🖥️ 🧪 🔓 ⬇️ journals.plos.org/ploscompbiol...

🐭 Thanks to the RefSeq team at NCBI, we now have an annotated genome assembly for the meadow vole (Microtus pennsylvanicus), found throughout eastern North America! (1/4)

after a long effort, gathering a lot of input from many people, we finaly put it all together: Ten Common Misconceptions About Galaxy (and Why They Are Wrong!) https://www.preprints.org/manuscript/202509.0823 Thank you very much to all people involved !

🎉 Big news! Galaxy Training Network workflows are now automatically registered on WorkflowHub. Easier discovery, citation, & direct Galaxy execution → boosting FAIR & accessible training! training.galaxyproject.org/training-mat...

I asked claude nicely, to come up with a small De Bruijn graph example for me. This is what it came up with (this is after 3 rounds of trying to get it to do better). The AI apocalypse is upon us!

📢 Venue confirmed! #Biocuration2026 will take place at Lagoon Beach Hotel, Cape Town 🇿🇦, April 20–24, 2026. ✨ Science, collaboration & stunning views await! 🔗 More info: www.bioinformaticsinstitute.africa/events/6/19t...

13 days to go until applications for Group Leaders are due ‼️ More details below ⬇️

From @biorxivpreprint.bsky.social | Out-of-the-box bioinformatics capabilities of large language models (LLMs)** | #Bioinformatics #Genomics #LLMs #OpenScience 🧬 🖥️ 🧪 🔓 ⬇️ www.biorxiv.org/content/10.1...

From @plos.org #Computational #Biology | Ten practical tips and tricks to improve the effectiveness of biological network alignment | #Bioinformatics #Education #OpenScience 🧬 🖥️ 🧪 🔓 CC/ @ppalagi.bsky.social ⬇️ journals.plos.org/ploscompbiol...

From @plos.org #Computational #Biology | Ten simple rules for training by researchers for researchers in a rapidly evolving workforce | #Education #Bioinformatics #PLOSCBTSR #Rstats #OpenScience 🧬 🖥️ 🧪 🔓 CC/ @carpentries.carpentries.org @rladies.org ⬇️ journals.plos.org/ploscompbiol...

From #OUP 's @bioinfoadv.bsky.social journal | Opportunities and considerations for using artificial intelligence in bioinformatics education | #Bioinformatics #Education #AI #LLM #OpenScience 🧬 🖥️ 🧪 🔓 ⬇️ academic.oup.com/bioinformati...

🌊 In 2023, the ocean carbon sink weakened for the first time in a record-hot year 🌡️🌎 Our new study in Nature Climate Change quantifies this unexpected decline and explains how it came about. 👇 doi.org/10.1038/s415...

From #NCBI Insight | Updated #Bacterial & #Archaeal Reference #Genome Collection Available from NCBI | #OpenScience #OpenData 🧬 🖥️ 🧪 ⬇️ ncbiinsights.ncbi.nlm.nih.gov/2025/09/02/b...

I don't speak French, but I still love the term "moronisation"!

La moronisation des États-Unis www.lapresse.ca/internationa...

The Disease Ontology's August release is now available 🎉 Learn about the Disease Ontology's 11,946 disease classes and latest updates at github.com/DiseaseOntol... #DiseaseResearch #Biocuration #Bioinformatics #FAIR #ComputationalBiology

From asfiston.bsky.social & colleagues in @plos.org #Computational #Biology | Why and how to set up a Bioinformatics Learning Lab (BILL) | #Bioinformatics #Education #OpenScience #OpenEducationalResources 🧬 🖥️ 🧪🔓CC/ @ppalagi.bsky.social ⬇️ journals.plos.org/ploscompbiol...

This is one of the most beautiful things I have witnessed, the craft here is impeccable.

From #NCBI Insight | #GenBank Release 268.0 | 258,320,620 traditional records containing 5,676,067,778,413 base pairs of sequence data | #OpenScience #OpenData #Bioinformatics #Genomics 🧬 🖥️ 🧪 ⬇️ ncbiinsights.ncbi.nlm.nih.gov/2025/08/26/g...

Want to explore biodiversity patterns? Galaxy’s Phylodiversity workflow lets you: 1️⃣ Match species occurrence data with a phylogenetic tree 2️⃣ Calculate diversity & endemism indices 3️⃣ Map phyloregions for conservation insights Try the tutorial 👉 training.galaxyproject.org/training-mat...

From @jxtxfoundation.bsky.social | JXTX + CSHL 2025 Genome Informatics Scholarships | Up to $750 for domestic or $1,250 for international travel | Application deadline is September 15, 2025 | #OpenScience 🧬 🖥️ 🧪 ⬇️ jxtxfoundation.org/news/2025-6-...

From @plos.org #Computational #Biology | Ten simple rules for being a co-author on a many-author non-empirical paper | #Education #Bioinformatics #PLOSCBTSR #OpenScience 🧬 🖥️ 🧪 🔓 ⬇️ journals.plos.org/ploscompbiol...

Sign up for our webinar on Tuesday 26th August on how new long read technologies (including the first CycloneSeq vertebrate genomes) are helping elucidate the sex determination of sex-changing reptiles cassyni.com/events/SWHRe...

The long-bodied mandarin fish joins the T2T genome club (and our T2T genomes thematic series) The telomere-to-telomere gap-free reference genome and taxonomic reassessment of Siniperca roulei doi.org/10.1093/giga...

From #NCBI Insight | Upcoming Changes to #GenBank Project Lists and Symlinks | #OpenScience #OpenData #Bioinformatics #Genomics 🧬 🖥️ 🧪 ⬇️ ncbiinsights.ncbi.nlm.nih.gov/2025/08/20/u...

From #NCBI Insight | #PubMed Central (PMC) Beta Search to Replace Current Search | #OpenScience #OpenAccess 🧬 🖥️ 🧪 🔓 ⬇️ ncbiinsights.ncbi.nlm.nih.gov/2025/08/19/n...

Coolest thing. @bffo.bsky.social, Ryan Brinkman & I started this cross-YVR bioinformatics seminar & networking series when you were lucky to see a sequence alignment in someone's talk. Ppl found collaborators, jobs, grad school supervisors, made friends, learned stuff. Still going after 23 years.

From the past: #VanBUG Nov 2002: Lincoln Stein (LS) is the invited speaker. In pic (L2R): @bffo.bsky.social, Roger Foxall (then @ @genomebc.bsky.social ), Steven Jones (@bcgsc.ca), LS, Ryan Brinkman & @stefaniebutland.bsky.social. 🧬 🖥️ 🧪 🔓 🇨🇦 #OpenEducationalResources ⬇️ www.vanbug.org/archive/2002...

From @bmc.springernature.com #Bioinformatics | GenMasterTable: a user-friendly desktop application for filtering, summarising, and visualising large-scale annotated genetic variants | 🧬 🖥️ 🧪 🔓 | #Genomics #OpenSource #OpenScience ⬇️ bmcbioinformatics.biomedcentral.com/articles/10....

From @amirbahmani.bsky.social‬ & Michael Snyder and colleagues in @medrxivpreprint.bsky.social | Achieving inclusive healthcare through integrating education and research with AI and personalized curricula | 🧬 🖥️ 🧪 🔓 #AI #Education #Research #Healthcare ⬇️ www.medrxiv.org/content/10.1...

Many have sworn off spreadsheets, others swear by them. Some swear profusely when they’re forced to use them. New @nature.com, six questions to make the most of your spreadsheets in science. 🧪 Feat @yabellini.bsky.social @cghlewis.bsky.social & more #datasci www.nature.com/articles/d41...

Release 53 of #Cellosaurus is ready: www.cellosaurus.org It contains information regarding 165'949 #celllines and cite 29'655 publications. Author name representation has changed from listing the surname followed by initials to a full-name format that spells out the given name(s) in full

From @plos.org #Computational #Biology | Ten simple rules for leading a many-author non-empirical paper | #Education #Bioinformatics #PLOSCBTSR #OpenScience 🧬 🖥️ 🧪 🔓 ⬇️ journals.plos.org/ploscompbiol...

From bioinformatics.ca | Call for CBW Instructors and Teaching Assistants | If you like to teach bioinformatics (and you are good at it) this is a great opportunity! | 🧬 🖥️ 🧪 🇨🇦 #OpenScience #OpenEducationalResources #Education #Bioinformatics #RStats ⬇️ bioinformatics.ca/workshops/fa...

“The path forward is… to embrace transparency. Inviting the public into the process of knowledge building will reveal why it is slow, imperfect, & indispensable. Science is a human endeavor w flaws & biases. Scientists strive toward truth by identifying & correcting those very flaws.“ #openScience

From #NCBI Insight | New Ranks in NCBI Taxonomy: Domain & Realm | #OpenScience #OpenData #bioinformatics #Genomics 🧬 🖥️ 🧪 ⬇️ ncbiinsights.ncbi.nlm.nih.gov/2025/02/27/n...

From @plos.org #Computational #Biology | Ten simple rules for research with humans | I like all of the rules, but particularly like Rule 2. Balance consent and confidentiality | #Education #Bioinformatics #Genomics #OpenScience #PLOSCBTSR 🧬 🖥️ 🧪 🔓 ⬇️ journals.plos.org/ploscompbiol...

📢 Update: Registration Deadline Extended! You now have until August 28 to register for EuroBioC 2025 and the pre-conference Bioconductor Carpentry workshops 🧬🛠️ If you haven’t signed up yet, there’s still time to join us in Barcelona this September! 🔗 eurobioc2025.bioconductor.org #EuroBioC2025

From Hangjia Zhao & @mbaudis.bsky.social in #OUP 's @bioinfoadv.bsky.social journal | #pgxRpi: an R/ #bioconductor package for user-friendly access to the #Beacon v2 API | #Bioinformatics #RStats @bioconductor.bsky.social #OpenScience CC/ @ga4gh.org 🧬 🖥️ 🧪 🔓 ⬇️ academic.oup.com/bioinformati...

🧬🖥️ I am strongly of the opinion that bioinformatics needs to move away entirely from text-based and "loosely" structured file formats for essentially any type of data. File formats should be binary-first, and designed for *correct* and *efficient* machine parsing 1/3

We already have sra, bam, cram, 2bit, ab1, scf, sff, CHP, IDAT, and others. For me, this becomes the Tower of Babel with no Rosetta Stone in a hundred years. Reversion to text (eg Bam to Sam) serves a human need. cc: @jbonfield.bsky.social @bffo.bsky.social @lh3lh3.bsky.social