Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

Huntingtin binds and bundles F-actin! Thrilled to team up with the Humbert (Sorbonne Université) and Song (KAIST) labs on this discovery. We had a blast doing cryo-ET on this unexpected complex — and now so many new questions lie ahead! #TeamTomo #CryoET #HTT #actin doi.org/10.1126/scia...

Please vote for Frankie’s image 👇 (if you like it!). Frankie is screening compounds to regenerate heart muscle. Your vote will help raise funds for this remarkable work.

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

#drosophila @flybase.bsky.social request emergency funding: "As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate! www.philanthropy.cam.ac.uk/give-to-camb...

Started my first day as a Walter Benjamin Fellow! 🥳 Looking forward to study symmetry-breaking in morphogenesis using and connecting concepts from soft matter physics & cell/molecular biology @yap-lab.bsky.social. 👉 physics meets biology! Big thanks to the @dfg.de for funding my research.

Our new review paper from @yap-lab.bsky.social is online - together with Virgile Viasnoff! 👉 'New directions in epithelial mechanoadaptation' www.sciencedirect.com/science/arti...

Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social www.science.org/doi/epdf/10....

📢Registration is open for our IPLS Annual Symposium, 11th June 2025! We will showcase exciting #interdisciplinary #research performed by IPLS researchers and collaborators. Limited spaces, register early to avoid disappointment 👇 ucl.ac.uk/physics-livi...

Has been added to our history collection on droso4public: droso4public.wordpress.com/history/

Flocking and active solid behavior of epithelial cells in our new study in @pnas.org Great work of Y. Shen, J. O'Byrne and @andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez! | PNAS www.pnas.org/doi/10.1073/...

We’ve had an incredible experience being hosted at the AIC at Janelia for iPALM imaging. Tremendous support and expertise. If your project could benefit from advanced imaging, check out their instruments (FIB-SEM, iPALM, LLSM and others) and get in touch.👇

If you train people in ImageJ, Fiji, whatever, even if it isn't your day job, please let us know, and please share this post! Thanks a ton, we really appreciate it. (2/2) forms.gle/C8dUpg8qZkbD... #bioimaging #microscopy #bioimageanalysis

Here we share our opinions on "Practical considerations for data exploration in quantitative cell biology" journals.biologists.com/jcs/article/... Joanna, Hanna and I worked quite a bit on this piece and I hope you find it useful Many thanks to @jcellsci.bsky.social for publishing it

For all you interested in small GTPase biology and membrane pattern formation - this is an essential read from the labs of Peter Bieling and Bill Bement www.embopress.org/doi/full/10....

We may not have really squared the circle — but we came close! 😉 In our @NaturePhysics paper w/ @fakhrilab.bsky.social, light-triggered membrane excitability enables programmable shapes — a step toward engineering living matter. 🔗 www.nature.com/articles/s41... #biophysics #syntheticcell #softmatter

AusBIAS is now on bluesky! We have a website, a logo, and a dream to connect all the bioimage analysts in Australia.

"How are memories formed and stored in the brain?...Long-term memory acquisition was found to be associated with a selective increase in multisynaptic boutons..". Groundbreaking new study from my friend and colleague Anton Maximov's lab: www.science.org/doi/10.1126/... Bonus: My son Luca's first pub

PREPRINT OUT ✨ "hack" your microscope to work as a 3D printer! print micrometer sized features at cm scale. a method for easy and cheap microfabrication, with a focus on biological applications. THREAD ↓ www.biorxiv.org/content/10.1...

Working on actin cytoskeleton and Arp2/3 complex? Check out our latest work～https://www.biorxiv.org/content/10.1101/2025.01.31.635869v1 In this work, we found SPIN90 forms a dimer, facilitating bidirectional actin filament nucleation by activating two Arp2/3 complex #Cryo-EM #Actin #Arp2/3

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me. Please amplify. If you are also able to host fly strains, add your name as well.

Announcing this upcoming conference: GASTRULATION RELOADED: Developing, engineering, and evolving the body plan Join us as we explore the latest research on gastrulation and axis formation/elongation, featuring common, exotic, and synthetic embryos! 📅 14–17 October 2025 📍 Paris, France

First official post! A new paper out about #cytokinesis in #epithelia www.embopress.org/doi/full/10.... Explore our journey as we uncover how regulators of cell-cell and cell-matrix interactions modulate cytokinesis efficiency, while revealing new roles for the Dystrophin-Dystroglycan complex.

If you're interested in theory in biology, please consider applying for this EMBO|FEBS Lecture Course "Emergence & Evolution of Multi-Level Regulatory Systems", organized by @yoginho.spore.social.ap.brid.gy, @nrepina.bsky.social, and James DiFrisco. meetings.embo.org/event/25-mul... #philsci #evobio

Interesting study by Delgado et al Lennon lab (@institutcurie.bsky.social), shows that Arp2/3 regulates Langerhans cells & nuclear shape, #cellmigration, and genome stability [In collab with @manellab.bsky.social, Benvenuti, Fachinetti, @sandraiden.bsky.social] Full www.biorxiv.org/content/10.1...

A long read from 2017 but well worth the time for any scientist who both loves their job and and often finds themselves questioning their life decisions. www.danielnettle.org.uk/wp-content/u...

14. There are huge benefits to converting your current journal clubs into preprint review clubs. *Share usable feedback and improve science *Help ECRs build a public track record *Actual training op-ed: buff.ly/3zjLltQ You could post the reviews to @prereview.bsky.social too! #PreprintAdvent

Important point from Editor of @plosbiology.org . See the two "Content verification" sections here journals.plos.org/plosbiology/...

We have a very cool (I know I am biased😁) project for a computational biologist (postdoc) interested in cancer evolution in collaboration with Nicky McGranahan’s lab! Perfect opportunity to expand your computational skills too! 👉 www.godinholab.com RT please 🙏🙏🙏👍👍

Our recent paper is now highlighted in #Kudos: link.growkudos.com/1pwlc1v9n28

I found a great excuse to make a bunch of fun ggplots. As if I needed one. github.com/thomasfelici... -- #rstats #generative #ggplot #rayshader

1/ One more preprint before the holidays! In which we find that chromatin compaction scales with cell size from interphase through mitosis. A collaboration from waaay back (see end of thread) with Melike Lakadamyali @melikel.bsky.social and Jerome Solon. A thread: 👇 www.biorxiv.org/content/10.1...

Here is a movie locally activating RhoA from our paper doi.org/10.7554/eLif... See fig. 4 for details. Our OptoLARG construct (pB3.0-optoLARG-mVenus-SspB-p2A-stargazin-mtq2-iLID) is adapted from this publication: doi.org/10.1038/ncom...

Sure! 🐌

Let's share some other classic, the beautiful Cells in culture film directed by Michael Abercrombie one of the father of quantitative cell imaging (University College London, 1955) is available here identity.wellcomecollection.org/works/z6h7jzv4

Mix two motors of opposite polarity with microtubules and they will partition space ! Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns. #morphogenesis doi.org/10.1073/pnas... (1/n)

New pre-print! To support a CDK-cyclin docking motif discovery and characterisation project led by Norman Davey and colleagues, @natalia-mg.bsky.social in my lab determined the #cryoEM structures of three peptide-bound CDK2-cyclin A complexes. Check it out! www.biorxiv.org/content/10.1...

🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1

Welcome to the #devbiolwriteclub Bluesky Boot Camp! I’ll be posting here regularly with thoughts and exercises to help scientists become better writers. Let’s start by managing expectations: I will NOT help you write better. I WILL help you become a better writer. 🧵 1/10

#CBIAS2024 attendees group photo. Is there a collective noun for a dense group of image analysts?

In May we published in #CellReports describing our study using high-throughput #lightsheet microscopy to investigate the #3D morphogenesis of melanoma cells during invasion, a process critical to #metastasis. Part of the Dynamical Cell Systems Team in-focus 2024. https://buff.ly/415jwBn

#Sentinal4D and my lab at the Institute of Cancer Research have developed Al methods to analyze videos of #cancer cells, and measure how #cellshape changes over time. We are using this technology to understand how drugs work, and find new cancer therapeutics. link.springer.com/chapter/10.1...

The strain on scientific publishing: we set out to characterise the remarkable growth of the scientific literature in the last few years, in spite of declining growth in total scientists. What is going on? direct.mit.edu/qss/article/... A 🧵 1/n #AcademicSky #PhDchat #ScientificPublishing #SciPub

We are happy to report that our journals and community sites now have Bluesky accounts. Follow them at: @dev-journal.bsky.social @jcellsci.bsky.social @jexpbiol.bsky.social @dmmjournal.bsky.social @biologyopen.bsky.social @the-node.bsky.social @prelights.bsky.social @focalplane.bsky.social

Here’s the updated Computational Biology Starter Pack! Let me know if you'd like to be included. go.bsky.app/QVPoZXp

At @rOpenSci.hachyderm.io.ap.brid.gy we're pairing first-time code contributors with experienced maintainers. If you are an rOpenSci or other #RStats package author and want to help build the road for new contributors and get co-maintainers, sign up for co-working! ropensci.org/blog/2024/10...

Pre-announcing the 10th Biennial European CellMech conference organized in Leuven 🇧🇪 from September 30th to October 3rd, 2025. cellmech2025.org Save the date !

Mitofilin/MIC60 in an U2OS cell, imaged with our latest generation oblique plane microscope (OPM). OPM is a light-sheet technique where both illumination and detection go through the same primary objective.

Check out our new paper in #eLife using high-throughput #microscopy and #imageanalysis, bayesian analysis and RNAseq to link single-cell NF-κB RELA nuclear translocation dynamics to actin dynamics in pancreatic cancer cells elifesciences.org/articles/86042 #hetereogeneity #PDAC #NF-kB #cytoskeleton

Even though there are great #devbio and #biophysics starter packs, I felt #morphogenesis & #organogenesis was missing as a subfield :D Far from complete or full. Tell me if you want to be added! go.bsky.app/PB6s8PQ