This piece discusses seven frontiers in RNA modification research. The examples cited highlight technological advances, regulatory principles both unique & broad-spanning, & questions about how biological information is post-transcriptionally encoded in chemical marks comprising just a few atoms.

I think there is a need for a complete re-think for organoid modeling. As long as the architecture of organoids that you produce is not directly compared to a 3D map of the organ (say, a fallopian tube) or disease to be modeled, it will be approximate. More here: www.science.org/doi/full/10....

This post is definitely a milestone for Merriam-Webster

Fil RH #CNRS d’avant le week-end #ESR Les données 2025 viennent d’être intégrées au sein du module Zento RH et donc je vous propose quelques mises à jour des informations RH générales au CNRS. Ne zappez pas, la suite va vous surprendre ! (oui, ici on est putaclic) 1/12

Scientific paper mill: the model flagged 10% of the research papers in cancer research as problematic 😱 www.bmj.com/content/392/...

Les fausses publications scientifiques menacent de submerger la recherche contre le cancer

Scientific paper mill: the model flagged 10% of the research papers in cancer research as problematic 😱 www.bmj.com/content/392/...

It’s finally out! Together with @embopress.org and @reviewcommons.org, we conducted a structured side-by-side comparison of human peer review and our AI scientific review (see thread 👇👇👇🔥).

10°C temperature anomalies...

The function of nuclear speckles is revealed! This is an incredibly important paper with absolutely beautiful data! Wow! www.cell.com/cell/fulltex...

#Drosophila calling. Delighted to share our new collection of ShineGAL4 drivers for CNS, FB, muscles, enterocytes, oenocytes and MTs made by @vgirard.bsky.social, @sebsorge.bsky.social and colleagues @crick.ac.uk. All at Bloomington @bdsc.bsky.social @dev-journal.bsky.social tinyurl.com/4jpw9jd6

DNA replication globally disrupts the epigenome. But does this create a chromatin-access opportunity for TF binding to facilitate cell identity change? Now 𝐫𝐞𝐩𝐥𝐢-𝐀𝐓𝐀𝐂-𝐬𝐞𝐪 shows 𝘥𝘦 𝘯𝘰𝘷𝘰 chromatin opening & TF binding occurs specifically post-replication, in cellular differentiation & reprogramming!

Join us for a day of talks, posters, and discussions, featuring a morning joint lecture with Nobel Laureates Eric F. Wieschaus and Christiane Nüsslein-Volhard! Date: Monday, May 4th, 2026 Location: University of Copenhagen, Mærsk Tower sites.google.com/view/emergin... Free to participate

Very excited to be advertising this project with the excellent cosupervision of Peter Mergaert through @i2bcparissaclay.bsky.social and @uniexecec.bsky.social. This position is open to international applicants and will involve stints in both Penryn UK and Paris France. Please share! Apply: adum.fr

Environ 336000 signataires pour la pétition contre Duplomb 2 : c'est trop peu ; et il s'agit vraiment de se réveiller pour empêcher cette mesure de destruction de notre santé (n'hésitez pas à republier ce post ou à alerter vos propres abonnés) : petitions.assemblee-nationale.fr/initiatives/...

Brainwashing, 2026 edition. This paper shows how X's algorithmic feed shifts people's views rightwards. It's a sophisticated, highly effective form of reorientation. And it is utterly chilling. If you're still on that platform, unhook yourself now. www.nature.com/articles/s41...

Bravo Liza, Brendan and colleagues for the elegant work on multiple live imaging strategies to untangle mechanisms of muscular dystrophy! www.nature.com/articles/s41...

Group Leader Call at the @cbitoulouse.bsky.social in Genome biology, projects at the interface with devbio will be given particular attention. please share :) cbi-toulouse.fr/wp-content/u...

Updated climate indicators graphics, now including 2025 ed-hawkins.github.io/climate-visu...

The registration is open! Junior #Drosophila PIs, join us for inspiring scientific discussion, contribute a talk and listen to our keynote speaker, Eugenia Chiappe. We meet in Palmela, Portugal from June 1st to 3rd. Register soon as spots are limited! congressos.mundiconvenius.pt/geral/inseri...

Happy to share scHiCAR, an ultra-high throughout (millions of cells), low cost (5 cents/cell including NGS), and trimodal platform for integrated single-cell level analysis of mRNA, open chromatin, and 5-kb resolution looping with ground-truth data the same individual cell.

🔬 Recruiting a Postdoc!!!! I’m looking for a motivated postdoc to join my lab and work on characterizing the role of a heterochromatin protein involved in a sex-ratio meiotic drive system in Drosophila. If you know someone who might be interested, please share widely!

This will feature an #EPIC scientific program. Something you have not seen before. Trust me 😉 CBG Alumni of all nations, unite!

Dear UK #drosophila @FlyBase Cambridge is now able to accept PO orders for support. So please get in touch with https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

Un poste de Professeur des Universités va être ouvert lors de la campagne d’emploi 2026 à l’université Claude Bernard Lyon1 - Profil Recherche : Biologie Moléculaire des Eucaryotes. Profil Enseignement: Biologie Moléculaire. Profil ci-joint. Merci de diffuser dans vos réseaux.

Expertise Before Augmentation: A developmental framework for sequencing AI use in PhD training doi.org/10.59350/ja1...

Spineless, Gutless RepubliKKKans.

Wow, big time preprint drop from @jacobsenucla.bsky.social lab! One of the holy grails of DNA methylation research. Also, the 2-figure paper reminds me of the classic Science Brevia from Simon Chan and Steve showing RNA-directed DNA methylation drives de novo DNAme www.biorxiv.org/content/10.6...

The New York Times reports that the Department of Homeland Security has sent Google, Meta, and other media corporations subpoenas for the names on accounts that criticize ICE enforcement. The department wants to identify Americans who oppose what it’s doing. I’ll save them time.

Sleep-dependent clearance of brain lipids by peripheral blood cells #Drosophila

Come join us for a great week of science in Dublin this summer! @brianstrahl.bsky.social @vanrechemlab.bsky.social @bonalditiziana.bsky.social @garcialabms.bsky.social @metorrespadilla.bsky.social

🚨🚨🚨 1/2 SFBD & JSDB joint meeting, June 9–12 in Hiroshima. Travel grants cover registration + part of travel/housing. Short talks & posters available. Students, postdocs & early-career researchers encouraged to apply by Feb 28. pub.confit.atlas.jp/en/event/jsd...

Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells Guest Editors: Alex Hughes (@hugheslabpenn.bsky.social) & Rashmi Priya (@rashmi-priya.bsky.social) Deadline: 1 March 2026 journals.biologists.com/dev/pages/ex...

Almost all of the scientists were previously at US institutions go.nature.com/4qMlrUR

The hard truth about how hard it is to publish in Development Editor-in-Chief @jamesbriscoe.bsky.social leads our team of Academic Editors in addressing the perception that Development is ‘too hard to publish in’ by discussing the journal's review process. doi.org/10.1242/dev....

Today, in news that shock nobody: "We found that none of the tested language models were ready for deployment in direct patient care. Despite strong performance from the LLMs alone, both on existing benchmarks and on our scenarios, medical expertise was insufficient for effective patient care"

#PressRelease🗞️ A specific molecular mechanism has been identified as the cause of the most frequent genetic forms of amyotrophic lateral sclerosis (ALS, also known as Charcot’s disease) and frontotemporal dementia (FTD). 👉 www.cnrs.fr/en/press/discov...

✨PPU Selection Week 2026 We welcomed 30 young scientists from 16 countries on our campus to dive into the heart of the PPU International Doctoral Program, offering a real immersion into what their next three years at the Institut Pasteur could look like 🎓 👉 www.pasteur.fr/en/education...

X-rays impact gene expression Exposing the wing discs of Drosophila to X-rays leads to heterogeneous changes in gene expression that are related to cell-cycle status and cell location. 🔗 buff.ly/6qXuLtV

Join the PALS Summer School in Transcriptomics🧬 🇸🇪 www.trippus.net/summerschool... and learn data integration -Single-cell multiome -ATAC-seq+3Dgenomics -Non-coding variants+Transcription Factors -Large-scale epigenomics -Spatial @scilifelab.se @kawresearch.bsky.social @remeseiro-lab.bsky.social

Apparently, USA asks your social media history for ESTA application since February 8th 👎 www.lefigaro.fr/voyages/cons...

Not something you see in textbooks very often: tripolar mitosis.

International AI Safety Report 2026 internationalaisafetyreport.org/publication/...

Here, the authors compile transcriptomic data from experimental evolution of a prokaryotic and five eukaryotic species in 22 environments to reveal that gene expression evolution is often repeatable and deterministic. www.nature.com/articles/s41...

The Centre for Research in Cellular Biology of Montpellier @crbm-montpellier.bsky.social is recruiting Junior/Senior Group Leaders. Check out the details on our cell biology jobs board: focalplane.biologists.com/cell-biology...

🧠⏰our latest paper is out now: how each neuron ages differently allowed us to define in silico screens for new therapeutic molecules that could prevent neurodegeneration @cecad.bsky.social @unicologne.bsky.social @uniklinikkoeln.bsky.social @meyerdh.bsky.social www.nature.com/articles/s43...

The latest #GENETICS study provides a detailed characterization of how yellow and white #Drosophila alleles affect ovarian response to a high sugar diet, demonstrating the influence of genetic background on behavior. buff.ly/Vr9WNkH

Make your gene knockouts more efficient with multiplexed Cas12a sgRNAs. Our new paper is out now, with tools available from @addgene.bsky.social , www.plasmids.eu and @vdrc-flies.bsky.social. www.nature.com/articles/s41... #CRISPR #geneediting #Drosophila 🧪🧬✂️🔬🪰 Summary 🧵 below.

A detailed characterization of the #Drosophila yolk-GAL4 transgene used for expression in the fat body shows that the Gal4 induces physiological defects in adult females. Learn more in #GENETICS about new alternative fly lines that mitigate this effect: buff.ly/SxA6L1E