In need of a positive outlook on the future (of developmental biology)? Read our perspectives by my fellow @dev-journal.bsky.social PI fellows and myself. I'm hoping my future will contain much more TE biology and mammalian genome regulation! journals.biologists.com/dev/article/...

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

The reality in science is that creativity is not treated as a core skill while hypothesis testing is, and that is the imbalance that we want correct through the Night Science Institute! www.technologynetworks.com/genomics/art... www.night-science.org

Great commentary, we all need to understand this

Hydra body axis balance: a fight between two transcription factors This Research Highlight showcases the work from Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios D. Tsiairis: journals.biologists.com/dev/article/...

Out in @science.org! We found that the intestine doesn’t just push out cells when crowded. Instead, cells are in a mechanical tug-of-war, and weaker ones are extruded. A new view of how our gut keeps its balance and stays healthy. www.science.org/doi/10.1126/...

What a week! A huge thank you to all the students and teachers for the for the engaged discussions, thoughtful questions, and good vibes. Rock on, and stay curious! 🤓 ✨ #VeniceEvoDevo #levels #morphogenesis #sysbio #evodevo

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

BIG NEWS!! We will be hiring a new professor with 25 years of endowed funding at the @biozentrum.unibas.ch @unibas.ch, focused on using biophysics and structural biology to explore climate-related fundamental science topics. Come start an innovative research cluster with us! 🧪🔬🧶🧬🌾🌍

We're happy to announce the 2025 International OME-NGFF workshop 🎉 📅 Dates: - Symposium: Nov 10–11, 2025 - Hackathon: Nov 12–14, 2025 📍 Location: Zurich, Switzerland Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...  #bioimaging #openscience #OMENGFF #OMEZarr (1/x 🧵)

A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics https://www.biorxiv.org/content/10.1101/2025.06.06.658228v1

Our latest "Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data" A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making Applied to ventral neural tube development www.biorxiv.org/content/10.1...

🚨📣 New preprint alert! Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos! A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social 📄 www.biorxiv.org/content/10.1... #devbio #mechanics

This is so reasonably wonderful!!!!! 🤩

My favorite NPR story blog - “Goats and Soda” sent a writer and photographer to a rural school in India; an early adopter of Foldscope. A wonderful photo story of kids “reading nature”. In this current challenging climate - the kids show us the way with joy and wonder. www.npr.org/sections/goa...

Last chance to come join us, don’t forget to apply (by tomorrow March 31st)!!!

Deadline is TOMORROW night (Mar 31). Not tonight, like wrongly announced at first. And that's good news: because you get another 24hrs to apply, if you have not yet done so! What are you waiting for!? 😉 Registration link below:

Our teachers this year: Mihaela Pavličev Mihaela co-chairs the Department of Evolutionary Biology at Uni Vienna. She studies mammalian reproduction to understand how organismal organization affects variation. She will present a model of tissue evolution based on metabolic interdependence.

Our teachers this year: Thibaut Brunet (@thibautbrunet.bsky.social) Thibaut studies the evolutionary origin of animal morphogenesis at Institut Pasteur in Paris. He will be teaching us about this and also how multicellularity first arose in evolution.

Our teachers this year: Wallace Marshall (@wallaceucsf.bsky.social) Wallace studies how cells solve engineering problems, how geometry arises within cells, and how it shapes and constrains cellular behavior. He'll be telling us how cell shape constrains underlying pathways.

Our teachers this year: Dan Brooks (@dsbrooks.bsky.social) Dan's research interests span the history & philosophy of the life sciences, concept usage in science & theory in biology. At our school, he'll have a thing or two to say about levels of organization, what they are & where they come from.

Well well, timely! 😉 www.cell.com/cell-systems...

Nature research paper: Topological segregation of stress sensors along the gut crypt–villus axis https://go.nature.com/4b4jcpC

Our teachers this year: Nicole Repina (@nrepina.bsky.social) Nicole is using quantitative imaging to study how complex tissue shape can emerge from cell interactions. In Venice, she will be speaking about how we can use imaging for multiscale analysis of multicellular systems.

Our teachers this year: James DiFrisco James is a philosopher of science and theoretical biologist working @crick.ac.uk on the evolution of gene regulatory networks, modularity and pleiotropy, vertebrate gastrulation, and the developmental basis of morphological homology/tissue organization.

📢‼️ Exciting new preprint from the lab by @nikhil-mishra.bsky.social et al, now out on @biorxivpreprint.bsky.social, reveals that the early embryo geometry spatiotemporally patterns zygotic genome activation (ZGA) in zebrafish. 🐟 tinyurl.com/Biorxiv-nmis... Read on to learn more... 👇

*** Registration deadline approaching! Apply to our Summer School in Evolutionary Systems Biology in Venice before MARCH 31, 2025 Reflect on your science in a beautiful and inspiring environment! Food & accommodation for the whole week are included in the course fee. Registration link below.

It's #FollowFriday #FF Follow this year's #VeniceEvoDevo teachers: @bensteventon.bsky.social @dsbrooks.bsky.social @thibautbrunet.bsky.social @wallaceucsf.bsky.social @rashmi-priya.bsky.social and organizers (James is extremely offline): @nrepina.bsky.social @yoginho.spore.social.ap.brid.gy

After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. www.nature.com/articles/s41...

Ski day at our joint @ehannezo.bsky.social @priscaliberali.bsky.social lab retreat! 🤗 #ischgl #austria ❄️☃️ @davidbrueckner.bsky.social

If you're interested in theory in biology, please consider applying for this EMBO|FEBS Lecture Course "Emergence & Evolution of Multi-Level Regulatory Systems", organized by @yoginho.spore.social.ap.brid.gy, @nrepina.bsky.social, and James DiFrisco. meetings.embo.org/event/25-mul... #philsci #evobio

Thank you for the highlight Rita! We also think these types of tools will open many new avenues, both fundamental and applied. And kudos for the very thoughtful and fair process @naturemethods.bsky.social

What a wonderful initiative in Alma's memory

Yamini @yamini-ravichan.bsky.social changed the topology of Hydra to show that actin orientational defects of Hydra induce the full program of head regeneration: www.science.org/doi/10.1126/... Mechanics controls development! Thanks to Dan Pearce, Karsten Kruse, Matthias Vogg & Brigitte Galliot.

Just in time for the holidays! Chapter 11 of #BeyondTheAgeOfMachines is here! A centerpiece of the book called "The Art of Modelling:" https://www.expandingpossibilities.org/11-the-art-of-modelling.html Including a number of illustrations by @mneustetter […] [Original post on spore.social]

check out my new dispatch article with @wallaceucsf.bsky.social in @currentbiology.bsky.social about cellular cognition! www.cell.com/current-biol...

What if plate tectonics had something to do with development? We found a new framework for dynamic origami in tissue folding in a nerveless animal. Will share thread; but if you are at #cellbio2024, see @cbrannon.bsky.social poster B399 today. Not at ASCB; read www.biorxiv.org/content/10.1...

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...

How can randomness be a source of living order? Can physics explain how an embryo emerges out of chaos? In this new paper in Science, Bernat Corominas-Murtra, @ehannezo.bsky.social & cols. show how embryos solve their own Rubik’s cube ist.ac.at/en/news/from...

Entropy is one of those formulas that many of us learn, swallow whole, and even use regularly without really understanding. (E.g., where does that “log” come from? Are there other possible formulas?) Yet there's an intuitive & almost inevitable way to arrive at this expression.

Super excited to announce my new lab at the University of Michigan opening Jan 2025! 🎉We’ll study how cells work together to shape the GI tract, with ties to regeneration & disease. Hiring at all levels—esp. a research tech to help launch the lab! Info: huyckelab.org #DevBio #CellBio #Hiring

Not in the genes.. and not in the hand-clapping either 😉

Entry-level position (80 - 100%) for bioimage analysis specialist at the Imaging Core Facility (IMCF) of the Biozentrum, University of Basel www.biozentrum.unibas.ch/open-positio... @unibas.ch #Biozentrum #Basel #research #science #joboffer #scientific

🚨Hyped to share our new article in @natureportfolio.bsky.social! We show that crocodile head scales develop from compressive folding that arises from constrained skin growth 🐊🔬 Really proud of this one - it's cool 😎 Please read & share! 🧪 @genevunige.bsky.social www.nature.com/articles/s41...

Brilliant!

What a nice perspective on the complexity of multicellular systems. Can a cell be defined by its interactions? We need to move beyond scRNAseq to categorize cell identity.

Membrane tension determines whether you get nibbled or gobbled 🤩

Do you know any cool papers about the multi-level nature of living and ecological systems? Especially papers that don't get enough attention? Modeling, experiments, philosophy, whatever. Let us know. We'd like to discuss them on here. #VeniceEvoDevo

Birds, bugs, microbes, dinosaurs, fungi, plants, algae, fish, rocks and minerals...everything in the natural world is worthy of art. If you post your nature art, nature journals, and/or sci art work and would like to join, please let me know! #sciart #birds go.bsky.app/ASnS846

Where does pattern come from inside cells? in this revised preprint, @aralbright.bsky.social Shows that regionalization of mRNA in a Stentor cell depends on dynein motors and the microtubule cytoskeleton doi.org/10.1101/2023...