So proud to watch Jana turn a side quest into an entire research programme. Couldn’t imagine a more well-deserved outcome. 😍 The mighty yeast reveals what we believe are general principles of centromere evolution! Behind the curtain: communities.springernature.com/posts/counti... #MEvoSky 🧪🌎

Last call for Les Houches! Apply now or never! ;) (ok, in 2 years again then) and share with your friends.

Job alert! We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? See also on the forum: forum.image.sc/t/research-e...

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Erdinc Sezgin to Receive 2026 Early Independent Career Award www.biophysics.org/news-room/er...

Congratulations @jiexiaolab.bsky.social . This is so well deserved.

Jie Xiao to Receive 2026 Carolyn Cohen Innovation Award www.biophysics.org/news-room/ji...

Sarah Veatch to Receive 2026 Agnes Pockels Award in Lipids and Membrane Biophysics buff.ly/AdSMhCT

Congratulations to @ceesdekker.bsky.social . This is so well deserved!

Cornelis (Cees) Dekker to Receive the 2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics buff.ly/fIexyZu

Please share: The application for Les Houches is open (until Oct 31) fluorescenceleshouches.wordpress.com *This is for you, if you ever wanted to learn all about fluorescence markers & how to apply them for your biological research!* PS: no fees this year, you just need to get there, that's all!

@embl.org Heidelberg is looking for a new Head of Scientific Instrumentation! This is an exciting opportunity at the interface between scientific research and technology development, overseeing our mechanical and electronic workshops! embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

🚨New preprint from the lab🚨 🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK. www.biorxiv.org/content/10.1...

To all post-docs: The Genome Biology dept ‪@embl.org has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

I’m excited to start my sabbatical at the EMBL in beautiful Heidelberg hosted by @sinemsaka.bsky.social Looking forward to learning more about DNA barcoding technologies, spatial omics, MINFLUX and more. Really excited about the exchange with all the amazing scientists at EMBL!

💥 We have 3 positions open in my lab in Basel, Switzerland🇨🇭: #nanopores #smFRET #biomolecular #dynamics #singleMolecules We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech. Please share broadly, thank you!🤝 schmid.chemie.unibas.ch

Our new non-denaturing nanoscale 3D DNA tracing technology provides single-cell (and sister-chromatid specific!) readout of chromatin structure with 10kb genomic resolution - Check it out! www.nature.com/articles/s41... Congratulations to Kai and Oyvind!!

🚨Join us! We're soon opening 3 postdoctoral positions in #AIDrivenBiology. Seeking biologists (especially microbiology and infection biology), computer scientists, and microscopy developers. Ideal candidates are those eager to use or develop next-gen tech for cell biology. Get in touch (DM/email)

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio meetings.embo.org/event/26-org...

Out latest preprint, from @cpane94.bsky.social in the lab, is out today! Maternal exercise rescues fetal akinesia-impaired joint and bone development. www.biorxiv.org/content/10.1... So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️

👇 Reminder on deadlines for i) early bird, ii) free child care option and iii) abstract talk selection! 👇

👉🏻 so glad to see this work out now ... a masterpiece conceived, led and driven by 👉🏻 Christoph Spahn 👏@michriscopy.bsky.social (🚨 #NewPI) and with great collaborations 🙏 @henriqueslab.bsky.social @seamusholden.bsky.social @gomez-mariscal.bsky.social

Here: Baby KJ at home with his mom Nicole. This really happened, folks. Hundreds of people from 8 organizations (led by Rebecca Ahrens-nicklas and Kiran Musunuru) came together to make a bespoke gene editor for this kiddo. He was once in the 7th percentile of body weight. Look at him now! ❤️

In case you needed a smile this Tuesday: 10-month-old baby KJ, who received a bespoke gene-editing therapy after a six month scientific sprint - "graduated" from the hospital @childrensphila.bsky.social today and went HOME! YAY SCIENCE! Here's his story: wapo.st/451ZQjT

🚨 New #preprint alert! We're excited to share our latest work: "Single-Allele Chromatin Tracing Reveals Genomic Clustering of Paralogous Transcription Factors as a Mechanism for Developmental Robustness in T Cells"🔗 tinyurl.com/4ve26tbd

We are happy to participate in the ARISE program and have a range of collaborative opportunities for various backgrounds including biochemistry, imaging, omics or lab automation. Get in touch if interested!

Our invited speakers : - Dominique Bourgeois - Johannes Broichhagen - Peter Dahlberg - Joerg Enderlein @joergenderlein.bsky.social - Ulrike Endesfelder @uendesfelder.bsky.social - Michelle Frei @michellefrei17.bsky.social - Dorus Gadella - Viktorija Glembocykte @glembockyte.bsky.social ../..

An incredible collaborative effort led by @kiranmusunuru.bsky.social @ahrensnicklas.bsky.social @urnov.bsky.social & others. Congratulations to @rachelsilverstein9.bsky.social who designed the Cas9 enzyme that went into this drug. Wishing K.J. & his family all the best 🙏

Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism" —the 1st human to undergo custom genome editing —from decades of NIH funded research www.nejm.org/doi/full/10.... @nejm.org www.nejm.org/doi/full/10.... www.nytimes.com/2025/05/15/h...

Excited to share our new @science.org paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals. www.science.org/doi/10.1126/...

For the first time, doctors have created a customized treatment using the revolutionary gene-editing technique known as CRISPR to treat a baby with a rare, life-threatening genetic disorder.

In a landmark scientific feat published in NEJM, a CHOP & Penn Medicine team treated the first patient with personalized #genetherapy, designed uniquely for newborn KJ, who was diagnosed with a rare #ureacycledisorder at birth. Learn more: http://ms.spr.ly/63327Sw92F

Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j49xBy

A baby named KJ, born with a rare genetic disorder called CPS1 deficiency, is thriving thanks to the world’s first personalized gene-editing treatment. 🧬✨ Doctors at @childrensphila.bsky.social used base editing—a tool invented by HHMI Investigator David Liu and his lab at Harvard.

Another breakthrough made possible by federal funding The result “is a triumph for the American peoples’ investment in biomedical research” Baby Is Healed With World’s First Personalized Gene-Editing Treatment www.nytimes.com/2025/05/15/h...

Inspiring story by colleagues from Penn Medicine, CHOP and others made possible by many years of federally funded research. Science saves lives! www.nytimes.com/2025/05/15/h...

How do altered levels of lamins and other nuclear envelope proteins contribute to cancer metastasis, and what role does #mechanobiology play here? Learn more in our recent review by fantastic Sarah Henretta, now out in NPJ - Biological Physics and Mechanics, open access: doi.org/10.1038/s443...

The amazing tour de force of the great @lcferme.bsky.social is now out in its final form in @ScienceAdvances (not on Bluesky???). It was hard work and all the conceptual advance was her doing. Check it out: www.science.org/doi/epdf/10....

Steven M. Block | 2025 Benjamin Franklin Medal in Life Science fi.edu/en/awards/la... youtu.be/yeZJXeQo3JQ?... via @YouTube

Lots of fun and great conversation about fluorescent proteins, probes, biosensors and Fret at @aqlm.bsky.social course at MBL. Also great to be in such close proximity to Shimomura GFP!

🔬 Science Through an Artistic Lens🎨 🧬Led by Prof. Maria-Elena Torres-Padilla, the #RepliFate Artist-in-Residence Program brings #artists and #scientists together. 👉 t1p.de/j5pi8 @epihmgu.bsky.social @metorrespadilla.bsky.social @ec.europa.eu @annadumitriu.bsky.social @replifate.bsky.social

Join us for the 2025 GRC Genome Architecture www.grc.org/genome-archi... @spp2202.bsky.social @jobdekker.bsky.social @metorrespadilla.bsky.social @jopkind.bsky.social @dimplenotani.bsky.social @stanleyqilab.bsky.social @andybelmont.bsky.social @fondufemittendorf.bsky.social @boyanbonev.bsky.social

Excited to to see our collaboration with @gburslem.bsky.social published today! This is part of our ongoing long term goal of achieving scalable non-disruptive and direct imaging and perturbation of the endogenous proteome

Excited to see this out in @science.org today!! www.science.org/doi/10.1126/...

AWESOME talk today by Melike Lakadamyali @melikel.bsky.social in the Cell & Molecular Biology Seminar Series @stjuderesearch.bsky.social! Very cool use of super resolution imaging techniques to understand how the cell works! 🤩 THANK YOU for visiting us!

Here is-🥳🥳😇 tremendous effort by @palmrinmoy.bsky.social brilliantly supported by @tamas-schauer.bsky.social &super help by federico,iliya,tsune,adam,@mamartirenom.bsky.social Very happy to see this come to fruition- Look forward to feedback from colleagues ! More 👉 www.cell.com/cell/fulltex...

Check out our paper, now extensively revised and published in @cp-molcell.bsky.social! This has been a real tour de force led by Stephanie Sansbury and @ysereb.bsky.social and we are very excited about the findings and future potential of this approach www.cell.com/molecular-ce...