In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...

What an amazing opportunity to work on cutting edge biology and biophysics with a great mentor. Apply!!!!

Unquestionably the result of combined effort from all current and former lab members, support from colleagues @CSU and @CU, and support from @hhmi-science.bsky.social and NIH over decades. A heartfelt 🙏 to my nominators and of course @vilcekfoundation.bsky.social. vilcek.org/prizes/prize...

on Holocaust Remembrance Day

Time by Luxmuralis at the Washington National Cathedral

Having grown up in a small Bavarian farming village of 600 people, it’s incredibly rewarding to finally be properly recognized. #Grassland #Pasture #MiaSanMia #MDPI

Gingerbread 2025 Dumpster 🔥

Janelia is hiring! "Invent new imaging methods, molecular tools, or protein chemistry approaches" www.janelia.org/content/lead...

Today I departed from @hhmijanelia.bsky.social knowing that the next time I come here, I will be a visitor. Thank you all for having me. I will miss you a lot.

Holiday party 2025 @hhmijanelia.bsky.social

Day 2 also covers Fourier Optics, with a fantastic lecture from Dr. Peter Kner! You'll never understand Fourier transforms better than you do after Peter explains it, trust us. Apply now to join us and finally understand #Fourier space! bit.ly/49YQl7q #microscopy

We are highlighting Jennifer Waters, a @focalplane.bsky.social Scientific Advisory Board member, Director of CITE, Harvard Medical School, and creator of MicroList (now featured in FocalPlane) and Microtutor, as an extraordinary biologist. #100biologists @jencwaters.bsky.social

Attempt number seven at uploading this video of intermediate filaments in an enormous COS7 cell. I have a feeling the BlueSky compression will not do it any favors.

We are happy to share our latest work, 4Pi-SIMFLUX, which combines structured illumination with interferometric detection to achieve near-isotropic 3D localization precision of 2–3 nm and resolve sub-10 nm structural features across whole mammalian cells. www.nature.com/articles/s41... rdcu.be/eQVxt

We moved the AI@MBL course "Deep Learning for Microscopy Image Analysis" to HHMI Janelia (@hhmijanelia.bsky.social). Join us for two weeks of intense lectures, exercise, and hands-on project work! Course dates: June 4-18 2026 Application by: January 15 2026 www.janelia.org/you-janelia/...

Oh no!

New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇 www.biorxiv.org/content/10.1...

TODAY (Sunday Nov 9th) starting at 4pm. Please join me in an interactive performance at the Athenaeum in Alexandria VA #interactiveart #performanceart

Exciting draw and late @fcbayernmunich.bsky.social comeback against Union Berlin in der alten Försterei. See you next Saturday morning when we play Freiburg at home #miasanfamily♥️ #washingtondc #MiaSanMia

Our photoswitchable HaloTag is out in Angewandte Chemie @angewandtechemie.bsky.social ! We now also show that this system can be used to control emitter density in SMLM. Congrats to Franzi, Bego, and our amazing collaborators. Check it out: onlinelibrary.wiley.com/doi/full/10....

Our confirmed count stands at 8.1 million participants worldwide for yesterday’s No Kings protest. Thank you to everyone who helped verify the numbers through our submission website. While some MAGAs attempted to submit false or misleading data (such as reporting “one person” for major cities)

Very excited to be co-organizing this meeting. Hope to see you there!

Maud Menten was born in Canada in 1879 and completed her UG and MD education at University of Toronto. As a research assistant with Leonor Michaelis in 1912, they wrote the classic paper describing the “Michaelis-Menten” model of enzyme kinetics.. #WomenInScience

Just heard him speak at Janelia just now. Wonderful talk!

(Part 1) Hear from @hhmi_news Investigator David Stern about his research program and what he's uncovering in the lab. Stern will join the Institute in February 2026, bringing his lab and HHMI appointment to Kansas City. @hhmi.org Read more: bit.ly/4np96Fb

"Her work made it impossible to separate what we learn from our obligation to protect it. Generations of researchers have tried to follow that example." - Jennifer Doudna (2/2)

The culmination of many years work. One of the most advanced light-sheet microscopes in the world! -> A large field of view Snouty light-sheet microscope, with any immersion remote refocus and real-time multi-angle projections! For details see previous posts and here: github.com/amsikking/HT...

Congratulations Jie! @jiexiaolab.bsky.social

🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/

Nobel laureate Jennifer Doudna tells Jeffrey Goldberg that vaccinations have been so successful that "there's been a collective forgetting that measles, and mumps, and rubella—these used to be diseases that would kill people in fairly large numbers." #TAF25 bit.ly/46a5DUE

Today’s work, aside from meetings.

@embl.org Heidelberg is looking for a new Head of Scientific Instrumentation! This is an exciting opportunity at the interface between scientific research and technology development, overseeing our mechanical and electronic workshops! embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

Beautiful work led by @oliveringe.bsky.social. It was great fun to be involved with this project. See Ollie’s paper and thread 👇

Thanks Misha for the shout-out! It has been a truly mind-opening journey. WHOLISTIC is one step towards whole-organism neuroscience and a true physiological observatory - with extensions on the way! I am continually amazed by what the data reveals - so much remains to be discovered and mined.

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

Results so stunningly clear they inspired this classic xkcd (xkcd.com/2400/):

This is absolutely the most significant glycobiology paper so far this year. Increasing cell surface N-glycosylation makes viable allo CAR-T cells without deleting the endogenous TCR #glycotime

Vaccines save lives, pass it on.

(1/n) A simple, ultrastable, and cost-effective oxygen-scavenging system for long-term DNA-PAINT imaging Please check out our new study on the benefits of sodium sulfite as oxygen scavenging system for DNA-PAINT. 👇🧵 #SuperResolution #DNAPAINT #SMLM #Microscopy

A new 25-camera multifocus microscope can capture 3D volumes of living organisms at high speeds. Using the microscope, the researchers were able to view a fruit-fly larva’s heart beating at about 2 Hz. Read the OPN story: bit.ly/4muEQbx #imaging #microscopy 💡⚛️🧪

One of the people I'm indebted the most for creating stunningly beautiful #mesoSPIM samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best #microscopy images & videos! www.linkedin.com/company/mart...

Clever mug :-)

Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday www.nature.com/articles/nme...

Wim Wenders war bei Alles gesagt? Der bedeutendste deutsche Filmregisseur unserer Zeit wird heute, am 14. August 2025, 80 Jahre alt.

We’re excited to welcome @kevin-dean.bsky.social to the #mesoSPIM2025 Symposium! Explore his innovations in Multiscale Cleared-Tissue Axially Swept Light-Sheet Microscopy for imaging from organ to subcellular levels. 🗺️Oct 13–15 | Zurich & hybrid Interested? Register now: t.uzh.ch/1Ss

I have some BIG NEWS to share today! Today I begin my next adventure as Chief Editor of Nature Biomedical Engineering!! (a thread) @natmethods.nature.com @natbiomedeng.nature.com @natureportfolio.nature.com

I still can’t believe that all NIH grants to my colleagues at Harvard and Harvard Medical School have been nullified. And that, as a nation, we’re somehow okay with this illegal, arbitrary, and petty act. Just think of the consequences: scientists, students, and patients will all suffer.

Nature Methods is hiring! We are seeking a new editor with expertise in microscopy, imaging technology, and/or cell biology. The position is available in NYC/Jersey City or Shanghai/Beijing on a hybrid working model. Apply by August 3! springernature.wd3.myworkdayjobs.com/SpringerNatu...

Fantastic talk by @hhmijanelia.bsky.social alumna and @embl.org group leader Dr. Claire Deo (@clairedeo.bsky.social). Stay tuned for her HHMI YouTube recording youtube.com/playlist?lis... #openscience @prevedel-lab.bsky.social @markkitti.bsky.social @kaydanych.bsky.social @rhodamine110.bsky.social