Under the hood of cells, scientists find clues to how tissues adapt to diet and disease | EurekAlert! www.eurekalert.org/news-release...

Scientists just discovered new "controllers" of the brain's most elite security checkpoint. Jiefu Li & team at our Janelia Research Campus have ID'd proteins that help open & close the blood-brain barrier — a step toward treating Alzheimer's, Parkinson's, & more: hhmi.news/4mkrDT2.

sOrganellomics is a new strategy to map cell state diversity and functional cell changes across healthy and diseased tissues! Check out the latest version now on BioRxiv - Congratulations @feliciano-lab.bsky.social !!

Really happy to see this beautiful story out! Looking forward to more collaborations like this @cristinapujades.bsky.social lab! www.biorxiv.org/content/10.1...

📢 Submissions are now open for the CellMap Segmentation Challenge. Build the best method for segmenting cellular organelles in vEM using our 289 annotated volumes, 40 organelle classes, and 22 diverse cell and tissue types. 🔗 hhmi.news/410evJQ

🔬 The Shroff Lab & collaborators have developed a new AI method that produces sharp microscopy images throughout a thick biological sample without using adaptive optics, adding additional hardware, or taking more images. 🔗 https://hhmi.news/3DLUEF8

🦠A team led by the Lippincott-Schwartz Lab used a new technique developed at Janelia called high-resolution template matching, or HRTM, to uncover in unprecedented detail the movement of ribosomes – the molecular structures that synthesize proteins inside cells. 🔗 hhmi.news/401LKMq

We are looking for exceptional #AIScientist|s to join our #AI@HHMI initiative at #HHMIJanelia. We want to uncover fundamental principles underlying complex biological systems that are inaccessible without new innovations that combine #AI with experimental design. ai.hhmi.org#join-our-team 1/4

I am happy to see our first manuscript already in bioRxiv! This collaborative work present a strategy to image and extract single-cell organelle signatures in tissues. Shout-out to all the authors! www.biorxiv.org/content/10.1...