🚨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimer’s shows superficial cortical Aβ cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @drneurochic.bsky.social authors.elsevier.com/a/1lxn85FFzL...

Why some people have more fit brain cells at 90 when others’ start dying at their 30s? Hard to say! It is hard to study because human 🧠 is the least accessible. @drneurochic.bsky.social et al discuss how to accelerate biomedical discoveries in brain health via transformative neuropathology. (1/5)

Every day is #InternationalWolfDay in our eyes, but today’s a great reminder of how amazing wolves are! 🐺 Support wolf recovery and conservation by donating or advocating for stronger protections. 🌎🐾 Learn more about ways to make an impact: nywolf.org

Interested to see how advanced microscopy holds the power to transform our understanding of therapeutics🔬🧠…come see our latest work. #AAIC25 Hall G session 2-3.30 pm integrative neuropathology in ADRD at 2.20 pm sharp @drneurochic.bsky.social

@alzassociation.bsky.social #GlobalImmersionExperience reception at Thompson Landry Gallery #Toronto

#USPOINTER study #sciencerockstars report #structuredlifestyleintervention improves #cognitiveperformance 🤓💪🏼🥳💜🧠 #ENDALZ

NEWSFLASH #2: @alzassociation.bsky.social commits over $40M to translate the positive outcomes of #USPOINTER #structuredlifestyleintervention to preserve your 🧠 💜 # ENDALZ 💪🏼 from global to local.

You can still be a grown a** adult and have an "I forgot my homework nightmare" ...There I sat in an audience and they call me as the next speaker and also from stage ask where my talk was😱 double booked today for two talks might have something to do with it😆 I'm excited though and pptx ready 💪

Thank you all for being great fan ❤

🧠 New preprint alert! We are excited to present the neurofibrillary tangle maturity scale, which integrates tangle maturity scores of pretangles, mature tangles, and ghost tangles to summarize tangle maturity predilection in the tissue. @drneurochic.bsky.social www.biorxiv.org/content/10.1...

academic.oup.com/brain/articl... My editorial on an actively immunised mouse model of NMDAR antibody encephalitis. Please note my scepticism of clinical trials in this field, towards the end!

Nominate a deserving early-career investigator today for a chance to attend #CCAD2026. If selected, they will compete for a $100,000, 2-year grant from #NewVisionResearch! View nomination criteria here 👉 newvisionresearch.org/ccad-2026/ Nominate here 👉 airtable.com/appjJE7FUGZY...

What you do makes a difference. 💚🩷 -E #GoodNews🏆 #GoodNews 🏆

Read our latest review article out in @thelancetneuro.bsky.social if you want to know more about CSF transport across the different compartments of the brain-meningeal border and its importance for neurological diseases with strong neuroimmune components 😉 authors.elsevier.com/a/1l7l75FFzL...

Learn about (generative) modeling in #ComputationalPsychiatry by attending the #CPCZurich2025. The BEST course for learning about different models (incl. tutorials), best practices, math backgrounds, and showcase your research in the poster session: www.translationalneuromodeling.org/cpcourse/

Curse of Neuroanatomy Training Part 4. Tessellation of Mona Lisa, but looks like gyri to us. Thanks to Dr. Jeff Browndyke. Original post by Kevin Atkinson Mathematical Tiling and Tessellation. #neuroskyence

ATTENTION New crowdsourced site collecting and sharing stories of public impact of research publicusaresearchbenefits.com Take a look and consider contributing. Let's make this as powerful as possible!

quite extraordinary story. Sometimes I think it’s the weird people that will save the world,

Today a pupal #Drosophila #Brain (40 h APF) for #fluorescencefriday. 🔵 Actin 🟠🟡 Anti-E-Cad depth-coded color I have 1 million versions of this picture, in which I tried different LUTs. I will put some in the comments! #microscopy #cellbio #neuroscience #insect

Our perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems. @jonykipnis.bsky.social www.nature.com/articles/s41...

For #FluorescenceFriday - new experiments that I am really excited for! Really pretty tyrosine hydroxylase (TH) 🟢 labeling in human induced pluripotent stem cells that are differentiating into locus coeruleus-like cells. Image credit to the @lieberinstitute.bsky.social Imaging Development team 🧠🧪🔵

So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠 🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this ~5min survey: alz.surveymonkey.com/r/923BTQK

@britishneuro.bsky.social has partnered with the Queens Reading Room! www.independent.co.uk/news/uk/home...

Huge congratulations to Professor Bess Frost on receiving your well-deserved Rainwater prize at #Tau2025🎉👏👏👏 Loved hearing your journey and resolve to dig in deeper when naysayers may have prevented your innovative discoveries rainwatercharitablefoundation.org/honoring-exc...

Love seeing the beautiful butterfly at #Tau2025 where 1000+ scientists and clinicians are gathering to share ideas to accelerate biomedical discoveries. Here is a starter pack to quickly follow TAUrrific researchers. Let me know if I need to add anybody go.bsky.app/KHno2VG @millermb.bsky.social

“The highest forms of understanding we can achieve are laughter and human compassion.”

Incredibly exciting times for regenerative medicine. Very happy to see the truly groundbreaking work led by the Tabar and Studer labs published. Huge congrats to all those involved!

Our @natrevimmunol.bsky.social review with @abhishekgarglab.bsky.social, @deadoc80.bsky.social and Kellie Smith is out! We attempt to integrate the data on CD8 T cell dysfunction into a new framework of hypofunctionality in cancer and chronic infections! www.nature.com/articles/s41...

I have over 2,000 followers. I never got to 800, after YEARS at The Letter. #ThankYou to the ~thirty people who actually check on me, for believing that I might have the occasional snippet worth reading. You are cherished. 🥰🙏🎉 -E

What a start for the inaugural Center for Neurodegenerative Disorders, featuring superstars @malutansey.bsky.social and @elizabethhead.bsky.social giving keynotes!

Had the pleasure of joining the inspiring Linde Jacobs from @curemaptftd.bsky.social for @npr.org "What's health got to do with it?" Listen in on a moving conversation on resilience as we fight with her and so many others against genetic destiny🧬🧠 npr.org/podcasts/103...

Open #Postdoc position @isd-research.bsky.social @lmumuenchen.bsky.social to develop an #iPSC-derived #BBB model. Fully funded and embedded in our international Foundation Leducq Network of Excellence www.brenda-leducq.de Experience in vascular biology or related field required. Please RP and apply

www.nature.com/naturecareer... UBC LSI Job!!

ICYMI: New online! Transcriptomics in the era of long-read sequencing

Wonderful way to start a beautiful morning at #ADPD2025 with @elizabethhead.bsky.social leading off the #neuropathology session in Hall C (2nd floor). Strong work highlightung efforts on Down syndrome to help us understand connections with Alzheimer's💙💜 www.nia.nih.gov/research/abc...

Excellent session on #tau this afternoon chaired by @drneurochic.bsky.social & Virginia Lee

Excited to share our findings on how APOE genotype impacts cell responses to AD using human brain snRNAseq. Huge thanks to the team for all the hard work! @drneurochic.bsky.social @mayoclinic.org @cp-neuron.bsky.social

Great working with Sujala Ghatamaneni, Val Lowe, and colleagues on this high resolution autoradiography study of MK-6240 and flortaucipir🧠🖥️ link.springer.com/article/10.1... @drchristinamoloney.bsky.social @davidjonesbrain.bsky.social

Stars in the sky or neurons in the brain? Happy Sunday! 🔬🧠

A&D: Behavior & Socioeconomics of Aging (BSEA) Editor-in-Chief @cgster.bsky.social representing the journal at #AAGP2025 Check out all the amazing research topics being published in #BSEA!

Our proximity proteomics study introducing Probe‑dependent Proximity Profiling (ProPPr) and applying it for profiling tau pathology‑associated proteins in tauopathies + @drneurochic.bsky.social & others is out now! @cziscience.bsky.social molecularneurodegeneration.biomedcentral.com/articles/10....

Today's #BrainWeekChat is all about education! When it comes to sharing the brain, what education resources do you reach for? Which do you recommend? Are there any you wish you had? #iTeachBio #EduSky #Neuroskyence #BrainAwarenessWeek @danafoundation.bsky.social

🤩Preprint alert👇 Excited to introduce the concept of transformative neuropathology, a term we use to describe the integration of foundational descriptive pathology with advanced technologies and methodologies 🔬🏛️🧬🧪🖥️🔬 🧠📊🤖 @cshlnews.bsky.social www.preprints.org/manuscript/2...

Ecstatic to see our paper "Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing" now published in @naturegenet.bsky.social with @trajnp.bsky.social and @panosroussos.bsky.social @sinaibrain.bsky.social www.nature.com/articles/s41...

Nice to see this finally published! Congratulations @jack-humphrey.bsky.social www.nature.com/articles/s41... (Collaborative work with Panos Roussos and his team! ) Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing

With so much horrible news at the moment- amazing to celebrate the legacy of someone wonderful and selfless! Having needed Anti-D injections myself it’s incredible to think my two boys were born happy and healthy because of science and amazing people like him.

We're delighted to congratulate the winner of the ECR Paper Prize, Angelika Zarkali! This award is presented to the first author of an outstanding study published in Brain Communications over the past year. Read more about the winning paper here:https://buff.ly/4idIsvN @angelikaza.bsky.social 🎉

What a great paper to start my Tuesday morning. Love these medial temporal lobe figures!!!

Excited to see this review of tau and TDP-43 come out, great to work with @lemwisse.bsky.social @relajoie.bsky.social and Bill Jagust 🤩🎉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

NIH funding directly translates into jobs, new medicines and economic growth. Spread the word! Modify this graphic for your lab: drive.google.com/file/d/17h_t...