Tristão-Pereira et al. investigate the local and global contributions of amyloid-β and tau to glucose metabolism in autosomal-dominant Alzheimer’s disease using PET. Read at 👉 buff.ly/p2noHnP #Alzheimers

Meet our team! Professor Bertram is one of our associate editors specialising in genomic, epigenomic and transcriptomic architecture of complex traits 🧠 #braincommunications #meettheteam

Pellacani et al. report that epilepsy with myoclonic-atonic seizures has diverse genetic causes, variable severity and outcomes. Early motor and language delays are strong predictors of poor long-term prognosis. Read at 👉 buff.ly/WLocWMY

De Grado et al. report that patients with restless limbs syndrome exhibit altered cortical excitability, impaired sensorimotor integration and abnormal nerve excitability even in clinically unaffected body regions. Read at 👉 buff.ly/PIHuNE3

Orekhova et al. investigated gamma oscillatory responses to repeated visual stimuli to assess short-term plasticity in the visual cortex of patients with visual snow syndrome. Read at 👉 buff.ly/0BKdUGE

Alfaro et al. report the case of a blind individual who participated in a clinical trial involving intracortical microstimulation of the visual cortex. Following electrical stimulation, the participant experienced a significant recovery of vision 👉 buff.ly/Ukpsa4E

Stoffel et al. report that patients with functional neurological disorders show altered brain responses when focusing on their heartbeat and experience greater difficulty in sensing bodily signals. Read at 👉 buff.ly/iOzZP0s

Lyons et al. review current evidence on biofluid biomarkers that may predict persistent symptoms following mild traumatic brain injury. They highlight specific markers linked to physical, cognitive and mental health disturbances 👉 buff.ly/ukO1gzY

We are delighted to announce that Professor David Belin has assumed the role of our Editor-in-chief! We at the Brain Communications family look forward to this exciting new chapter! #neuroscience #braincommunications #meetheteam

Read Thorsten Rudroff's scientific commentary which refers to ‘Systemic increase of AMPA receptors associated with cognitive impairment of long COVID’ by Fujimoto et al. (buff.ly/hUGyviF). Read the commentary at 👉 buff.ly/4rBx2mZ

Spires-Jones and Tulloch conducted an experiment studying teaspoon 🥄 pilfering from their departmental common room. They observed gold teaspoons disappeared faster than standard spoons. Full article here : buff.ly/lFdjgxt #replicationstudy #neuroscience #aprilfoolsday

Requena-Komuro et al. found experienced duration of everyday sounds is altered and time sensitivity is reduced in people with different dementias compared to older controls. Time awareness signatures in dementia reflect brain atrophy profiles 👉 buff.ly/XyD1zDI

FDG-PET effectively differentiates vegetative state from minimally conscious state in chronic patients, although its diagnostic accuracy can be affected by etiology. The presence of resting-state fMRI networks is associated with increased metabolism levels. Read at 👉 buff.ly/VSrkGGw

We are grateful to all those who attended the Brain conference 2026! We would like to also thank all those who came and gave us truly inspiring talks and poster presentations. #brain2026 #neuroscience

Fukushi et al. study that intravenous infusion of mesenchymal stem cells reduces neuropathic pain by reversing abnormal dendritic spine structures in the spinal cord and, importantly, in the brain 👉 buff.ly/5w1g69K

We are delighted to announce the winner of our Early Career Researcher award! Read the paper by Dr Zanna Voysey and the team 👉 buff.ly/C5C53p5 #ECRaward #neuroscience #brain2026 @zannavoysey.bsky.social

Cler et al. show analysis of subcortical nuclei in a large sample with a range of language abilities (N = 156). Smaller neostriatal volumes were associated with DLD as predicted. Smaller volumes were reported for the hippocampus, pallidum and thalamus 👉 buff.ly/GD14z2B

Ingvarsson et al. report that serological evidence of infection with human herpes virus 7 is associated with a higher risk of developing multiple sclerosis. They also report a synergistic interaction between human herpes virus 7 and Epstein–Barr virus 👉 buff.ly/PWp4AnP

Jiang et al. report that reduced cortical gyrification in amyotrophic lateral sclerosis is associated with white matter tract degeneration and clinical disability. 🧠 Read at 👉 buff.ly/XoOyQTN

Martinez-Heras, et al., described longitudinal functional connectivity in multiple sclerosis using graph metrics. They identified distinct trajectories linked to cognitive performance, supporting two mechanisms of brain adaptation. Read at 👉 buff.ly/3AYKphC

Eller et al. report the generation of a novel mouse model of ECHS1 deficiency that recapitulates features of human disease, including sleep disturbances, epileptic activity and inflammation sensitivity 👉 buff.ly/VgZhpzu

Patients with chronic pain often report poor memory. Forkmann et al. found that patients with chronic back pain and chronic migraine do not show greater disruptive effects of experimental pain on episodic memory than healthy, pain-free individuals 👉 buff.ly/D0gbQVq

Taylor et al. report that children and adolescents with greater peripheral inflammation, as measured from saliva, show significant aberrations in multispectral neural dynamics supporting attention processing. 👉 buff.ly/etWpyEy

Tomlin et al. examined the temporal changes in synapses and glial cells in a mouse model of Alzheimer’s disease. They found that inhibitory synapses are the earliest change in NL-G-F mice with concomitant molecular changes in glial cells 👉 buff.ly/m1YEnil

Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative disorder affecting fragile X gene premutation carriers. Symptoms include tremors, balance issues and dementia. 👉 buff.ly/1k9Fotu

Van Vugt et al. report that genotyping 39 disease-associated short tandem repeats (STRs) in 8531 Project MinE samples revealed pathogenic C9orf72 and ATXN2 expansions significantly associated with amyotrophic lateral sclerosis 👉 buff.ly/UjYrc1w

Peylo et al. (2025) report a series of experiments which probed visual search improvements through transcranial direct current stimulation over the frontal eye fields. Their results provide no evidence for stimulation-specific visual search improvement 👉 buff.ly/TB2vMOn

Parker et al. find that accelerated long-term forgetting in familial Alzheimer’s disease is mediated by neurodegeneration in the prefrontal cortex and not medial temporal structures or white matter connections 👉 buff.ly/XTngTUP

Song et al. show that visuospatial impairments after stroke follow distinct anatomo-behavioural patterns across recovery phases. Acute symptoms primarily reflect lateralized attention deficits to frontoparietal damage and interhemispheric disconnections 👉https://buff.ly/7XnwLTm

Li et al. report that functional connections between the thalamus and cortical and subcortical regions at term-equivalent age predict severity of neurodevelopmental impairment outcomes at two years in preterm infants 👉 buff.ly/jtIBDfT

Bu et al. reported distinct spatiotemporal iron accumulation patterns in Parkinson’s disease motor subtypes: an inverted U-shape in postural instability and gait difficulty subtype and an S-shape in tremor-dominant subtype as disease progressed 👉 buff.ly/vwRxQti

Schweitzer et al. examined how age and sex influence cerebrovascular dysfunction across the lifespan in an Alzheimer’s disease mouse model. Read at 👉 buff.ly/pQRT6M7

High-resolution retinal imaging reveals immune cell infiltrates in the inner retina of MS patients, particularly after optic neuritis. These cells may serve as early, non-invasive biomarkers of neuroinflammation 👉 buff.ly/QH2t3yh #MS #OpticNeuritis #Biomarker

Read our final editorial from our founding editor-in-chief Tara Spires-Jones introduces the new editor-in-chief, Professor David Belin from University of Cambridge, UK. 👉

Leguia et al. characterize sleep cycles repeating over a month in eight participants wearing a sub-scalp EEG recording device. Although the symphony of sleep waves varied across participants, shared dynamics at sleep stage transitions were found 👉 buff.ly/E7rKJBj

Leckey et al. report novel measures of neurofilament light chain kinetics in the human central nervous system using stable isotope labelling. Translation occurs within hours, but appearance in cerebrospinal fluid takes ∼100 days 👉 buff.ly/NppPWZw

Our newest issue is live with a shiny new cover image! The image created by Janis Malcomson is based on work by Leckey, Giovannucci et al., who developed an assay to measure proteins and their clearance from cerebrospinal fluid. buff.ly/H8HNMGU

Shapiro et al. report that inflammation PET signals in subcortical regions and plasma neurofilament light levels are complementary prognostic biomarkers in progressive supranuclear palsy, demonstrating greater sensitivity than other measures. Read at 👉 buff.ly/MXQKI3H

Berntsen et al. investigated the relationship between delirium and the protein YKL-40 in cerebrospinal fluid. They found that concentrations of YKL-40 were increased in delirious hip fracture patients without dementia 👉 buff.ly/PDmGc6D

A new study maps how brain lesions disrupt sensory processing, revealing a cross-modality network linking the substantia nigra, and cerebellum. The cerebellar vermis sensory is a convergence point for sensory processing and hallucinations 👉 buff.ly/CX9aIhw

Guragai et al. report that identical twins show stronger similarity in brain connectivity linked to intelligence than fraternal twins. Using resting-state functional imaging, they demonstrate that genetic factors shape intelligence-related connectivity 👉 buff.ly/R7zvYjR

Submissions are now open for #BNA2027 – the International Festival of Neuroscience! We’re inviting proposals for symposia and workshops that showcase excellent science, support #ECRs, and reflect the diversity of #neuroscience. 🔗 Guidelines : www.bna.org.uk/events/bna20... #CallForSessions

Sirolimus, an mTORC1 inhibitor, was tested as adjunctive treatment in a mouse model of pneumococcal meningitis. Sirolimus worsened clinical severity and increased inflammation, elevating IL-6 and IL-12 levels. Read at 👉 buff.ly/uiVhwGq

Schüller et al. found that individuals with Tourette syndrome show impaired behavioural and neural adaptation to changing cue predictability during a motor cueing Posner task. Read at 👉 buff.ly/4hDGZNW

Samuel et al. report probabilistic brain maps of glioma derived from over 2000 patients across eight datasets. Tumour location was linked with molecular subtype, age and survival 👉 buff.ly/ymqVgiL

Liu et al. used a multi omics approach to discover and validate a series of genes expressed in plasma that are associated with the risk of stroke and its subtypes. Read at 👉 buff.ly/TXnkWic

Frontzkowski and Hunze et al. show differences in brain network architecture influence stroke recovery. Patients with more efficient and less modular structural networks in the contralesional hemisphere experienced more favourable long-term outcomes 👉 buff.ly/EwNNgVw

Saini et al. report no evidence of genetic interaction between SNCA and APOE in 8855 synucleinopathy patients and 11 067 controls. The authors found no evidence of genetic epistasis between these genes 👉 buff.ly/PER2aEq

Albanese et al. report on a peculiar and rare phenotype observed in a tertiary movement disorders centre. The patients presented a functional movement disorder with sustained shoulder elevation posture, frequent pain, and no identifiable cause 👉 buff.ly/hCd1juP

Jiang et al. showed that 5-year follow-up data from 102 children with 5q-spinal muscular atrophy who received disease-modifying therapy revealed improvements in motor function, growth status and frequency of complications 👉 buff.ly/ZYR1KhD #neuroscience