Please come join me in Washington, DC August 2-6th for the FASEB SRC on Cilia and Centrosomes meeting! Over 40 talks will be selected from abstracts. We are also excited to launch our first North American Ciliopathy Summit, held at the same venue on August 2. events.faseb.org/event/cilia-...

Hey y’all 👋 repost magic appreciated. The Solecki lab is recruiting multiple postdocs at St. Jude for a chromatin imaging project at the edge of live-cell imaging, neuronal cell biology, chromatin regulation, and quantitative image analysis. Ever dreamed of touring chromatin like this? We CAN 🔥

Preprint 🧵! I’m really excited to introduce BIGSMALL, an interleaved multi-magnification cryo-ET scheme bridging molecular and cellular scales in a single acquisition! BIGSMALL = 𝐁road 𝐈nformation 𝐆athering 𝐒trategy by 𝐌ultiscale 𝐀cquisition of lame𝐋𝐋a www.biorxiv.org/content/10.6... (1/6)

Calling all #cilia researchers. Our new Community Page presents CiliaKB, a manually curated #KnowledgeBase that serves as a one-stop platform for researchers to rapidly access mechanistic #data and mine for translational clues about cilia. 🧪 #CellBiology plos.io/4d4QaYr

Whoa. Check out this tardigrade eye, comprised of just four cells, one of which has a cilium (CI) that expands into a labyrinth (orange, outer segment equivalent?) with ciliary Opsin. See preprint from Soumi Dutta, Vladimir Gross, Georg Mayer and colleagues: www.biorxiv.org/content/10.6...

On April 19, 1898, Camillo Golgi first described what we now call the Golgi apparatus - a structure so striking and unusual that it took more than 50 years for scientists to accept it wasn’t just an artefact. April 19 is #GolgiDay! Celebrate the cell’s most iconic and best organelle.

Original image from 2011 of what I just had seen under the microscope when I ran into @oliverrocks.bsky.social’s office to show him. Turned out he’d observed this too, had no idea what it was either, but was just as stunned and curious as I was. This is how it all started... /1

Rods have a continuous multilamellar architecture - unlike any known cellular membrane organisation - and occur across all cell types tested /3 🙏 @andimicroscopy.bsky.social

Happy to have contributed to this. Really exciting findings on new structures in cells. Congrats to @pm-mueller.bsky.social, @oliverrocks.bsky.social and everyone involved.

I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

Molecular architecture of the ciliary base in mammalian multiciliated cells https://www.biorxiv.org/content/10.64898/2026.04.05.716577v1

In their Review, Prasanna Katti, Antentor Hinton, Jr and colleagues discuss how imaging techniques have advanced our understanding of mitochondrial biology. journals.biologists.com/jcs/article/...

We've spent the last year building something at @humantechnopole.bsky.social that we think is genuinely needed: #AI that works across biological scales and data modalities, not just within them. A thread on what we're doing, why, and who we're looking for. A 🧵... 1/9

📣 The Cilia2027 Best Image Competition is open! 🧬✨ 🏆 1st Prize: Cover of the program & website + FREE registration to Cilia2027 🥈🥉 2nd & 3rd: Featured in the event screensaver + website Submit your best cilia visuals: forms.gle/jUC2tnsa5Cs8... #Cilia2027 #Microscopy #SciArt #Cilia

The new release of #BigVolumeBrowser (0.1.0) finally adds animation render functionality to it, plus some other navigation improvements and bug fixes. Here is a movie I've made for the microtubule network (via ExM) in different cell types. Contact me if you want it for educational/research purposes.

🚨Job Alert -- again!🚨 You are into disease risk prediction based on images or other data modalities? This is for you! 🫵 careers.humantechnopole.it/job/Postdoc-... Part of our Scientific AI Flagship @humantechnopole.bsky.social and part of our mission to benefit society via biomedical #AI solutions.

A unique opportunity to lead the most wonderful company in scientific publishing (I might be slightly biased here). The Company of Biologists are searching for a CEO. www.inspiredselection.com/jobs/jo00000...

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...

For #BrainAwarenessWeek, I'm hosting 'That Sugar Film' at #ThaliaKino on March 18th. After the film, Luise Molling (@foodwatchde.bsky.social), Friedrich Johenning (#ChariteBerlin) and I will discuss the impacts of sugar to the 🧠and to society! Tickets here: www.kinoheld.de/Kino-Potsdam...

Excited to share our new paper (CVPR 2026 🚀): "MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy" which enables local predictions to use global context. Great work led by @albertdm.bsky.social & another fun collab w @gioelelamanno.bsky.social! @scadsai.bsky.social

We opened 4 PhD positions at @humantechnopole.bsky.social together with Polimi (see 👇). My lab offers a PhD project on "Computational Morphogenesis": use state-of-the-art machine learning methods together with realistic simulations to build digital twins of developing tissue. Apply by March 26.

Looking for a theory partner for an #HFSP project? #morphogenesis in cells and tissues, #chemotaxis, #cilia? Feel free to reach out! Deadline for letters of intent 26.03.2026. physics-of-life.tu-dresden.de/team/pol-gro...

pH-dependent trapping of cationic amphiphilic drugs perturbs insulin granule homeostasis https://www.biorxiv.org/content/10.64898/2026.02.19.706757v1

AI based analysis of human pancreatic histology provides a foundation for future research into relevant diagnostic and therapeutic targets, refining several hypotheses regarding tissue alterations associated with #T2D www.nature.com/articles/s41...

There are just a few days (and spots!) left to apply to this EM course with a focus on marine samples 🌊 do not miss it!

🌍 Cilia2027 | Mar 8–12, 2027 | 📍 Stresa, Lake Maggiore, Italy Join the global cilia community for science, collaboration & discovery (+ fun!!). #Cilia2027 #CiliaBiology

Villin-SNAP25 interaction regulates insulin secretion downstream of ICA512 signaling https://www.biorxiv.org/content/10.64898/2026.01.13.699220v1

🔬🔦Our latest ‘Imaging spotlight’, by @carlesbosch.bsky.social, Ana Diaz, @adrianawanner.bsky.social & @andreas-t-schaefer.bsky.social, highlights the non-destructive X-ray tomography pipeline that the authors developed to map mouse brain ultrastructure & considers future applications & developments.

Microscopy Bat signal! I want to compile a list of biological samples that demonstrate microscope capabilities, including the reagents to generate them. Please send me anything you know of!! Beads are great for QC, but there's a different teaching benefit with biology. 1/n

20-plex volumetric super-resolution imaging of cellular ultrastructure. Preprint, led by @seweryn-galecki.bsky.social, dropping soon.

Surprise mother$#@%er! Q: What does this mean for neural systems to understand them? A: We absolutely need the wiring diagram. All synapses, chemical and electrical. #Connectomics

Happy that we could contribute to this amazing study.

💥I am excited to present our first research paper from the lab about caveolae lipid trafficking 🎉 Led by my fantastic PhD candidate @estherocket.bsky.social Here we looked into caveolae mediated dietary lipid uptake and how this process is mechanistically facilitated 👇 1/n

Our Method of the Year 2025 is...drumroll please...EM-based connectomics!! Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬 www.nature.com/articles/s41...

The TUD has made a very nice video in their "Kurze Frage" series featuring PLID member Andreas Müller where he explains how insulin is produced by the beta cells of the pancreas and why this is important in diabetes (German only) #TUDresden #DiabetesResearch #PLID #HelmholztzMunich

Here is a short video by @tudresden.bsky.social (in German) of me explaining what beta cells do and talking about our research on investigating the structural features of their function and dysfunction.

Interested in applying U-ExM to cells, tissues, organoids, or cryo-sections? Our EMBO workshop is open for applications! 🧫🔬 Deadline: 12 Jan 2026 — don’t miss it!

Do you have 2D-to-3D image registration challenges? Let me know about them here forum.image.sc/t/toward-bet...

Our new paper showcasing molecular connectomics with pan-expansion microscopy is out in @natbiotech.nature.com! www.nature.com/articles/s41... This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)

#Cilia and #Centrosome friends- tomorrow is the big day!! 🎉 🎉 Organoids for #PCD, #CryoET of the base of motile cilia, TZ organization in #IRDs, macrophages & cystic niches in #PKD, how pro-inflammatory lipids & #adipogenesis AND cilia as signal-sending organelles shedding #EVs! 🤩 😍 Join us!!

Scientific journals: we don’t want you using generative AI because it makes shit up. Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote Same journal: AI cover art which makes no sense? Oooh!

Calling on my #science network! TeamNDF is #hiring a postdoc to start in 2026! Are you fascinated by metabolism and the brain? Do you want to dig into life long impacts and the molecular cause? Learn more about the team and our research here: www.dife.de/en/research/... Please share! 🧠 🍔 💉

New on bioRxiv! 🚨 “Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature” This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia! 🔗 www.biorxiv.org/content/10.1... 🧪 🧵1/8

We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji. It ships many new features, detailed below, but that are articulated around the following:

My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site #microscopy #ImageJ #FluorescenceFriday #microscopyMonday imagej.net/plugins/imag...

As a neuroscientist, I’d suggest there is a profound disconnect between what *some* computer scientists think is representative of “intelligence”, cognitive ability, or descriptions of consciousness from some in AI work. LLMs are not how neural systems process information, nor how brains function.

We are looking for motivated #postdocs to join the lab! Biochemistry/microbiology/cryo-EM experience? Excited by #cryo-EM/ET, #chromatin? ❄️🧬🧫 Interdisciplinary projects, top EMBL facilities! Email CV + short cover letter → [email protected] Info about the group: www.embl.org/groups/dodon...

Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🤩🤩🤩

Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social‬ and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI. journals.biologists.com/jcs/issue/13...