🔬🔦Our latest ‘Imaging spotlight’, by @carlesbosch.bsky.social, Ana Diaz, @adrianawanner.bsky.social & @andreas-t-schaefer.bsky.social, highlights the non-destructive X-ray tomography pipeline that the authors developed to map mouse brain ultrastructure & considers future applications & developments.

Here's a spotlight article on our recent study! Tissue ultrastructure can be resolved with X-rays, which impacts not only how we can study neuronal circuits but soft tissues more generally. Kudos to Ana Diaz, @adrianawanner.bsky.social, @andreas-t-schaefer.bsky.social and all authors.

An optimized X-ray nanotomography method offers an attractive alternative to volume EM for connectomics. @crick.ac.uk @psich.bsky.social psich.bsky.social @adrianawanner.bsky.social @andreas-t-schaefer.bsky.social @ucl.ac.uk @uclnpp.bsky.social www.nature.com/articles/s41...

By repurposing a radiation-hard epoxy resin from the nuclear/aerospace industry, we made samples withstand >1.15×10¹⁰ Gy and reached sub-40 nm resolution, revealing axons, dendrites, mitochondria and synapses without sectioning.

In a fantastic collaboration co-led by Ana Diaz (@psich.bsky.social), Carles Bosch @carlesbosch.bsky.social) and Andreas Schaefer (@andreas-t-schaefer.bsky.social) from @crick.ac.uk,we tackled a key barrier in X-ray ultrastructural imaging: achieving <40 nm resolution without destroying tissue.

X-rays can resolve ultrastructure - milestone for ultrastructure imaging w/o cutting. Thanks to an amazing team - @carlesbosch.bsky.social @adrianawanner.bsky.social Ana Diaz and collaborators @crick.ac.uk @psich.bsky.social and @esrf.fr and funders @wellcometrust.bsky.social @ukri.org

Enthusiastic about connectomics and X-rays? Several positions in our group at Crick for postdocs and senior scientists (permanent!). DM me if interested – and let’s talk if you are at Sfn next days or at the NIH BRAIN CONNECTS meeting today! Please share!

Join us at Crick - amazing team and great colleagues to collaborate on exciting design and development projects

Bit more than 2 weeks to go... DM me if you will be in San Diego at SfN and want to talk about it. Please share.

Very excited to continue our amazing collaboration with @apacureanu.bsky.social at @esrf.fr - thank you @wellcometrust.bsky.social and all the collaborators at @crick.ac.uk and @esrf.fr

The Crick is an absolutely amazing place to work in - please share this opportunity widely with your colleagues and postdocs - and DM me if I can help in any way

Judging by the last ones, this will be amazing - and with all the new developments at next gen synchrotrons, even more timely. Please re-post, join in person if you can travel to London or via zoom

Motivated graduates with backgrounds in biological or biomedical sciences, physics, chemistry, mathematics, engineering and/or computer science are invited to apply to our 4-year fully funded PhD programme. Apply by 05 November 2025 www.crick.ac.uk/careers-and-...

The Molecular Brain Mapping group at the MRC-LMB is hiring! 🌈🧠 I'm looking for people who are excited about developing multimodal analysis and visualization tools to capture the "hidden connectome," in a highly intersectional environment exploring ideas in meta-science. mrc.tal.net/vx/mobile-0/...

Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!

Great opportunity to work with an amazing team on the frontiers of X-ray connectomics www.psi.ch/en/hr/job-op...

Applications are now open for the SWC Systems Neuroscience PhD Programme. Join us in London! 🧠 World-class neuroscience training 💰 Fully-funded 4-year programme 🖥️ Close links to @gatsbyucl.bsky.social Apply by 3 Nov: www.sainsburywellcome.org/web/content/...

#preprint: We optimised the preparation of tissues for #X-ray phase contrast imaging. Drying tissue samples (instead of embedding them) brings more signal in #X-ray phase contrast images. The process largely preserves #ultrastructure. @safekhan.bsky.social @andreas-t-schaefer.bsky.social

Our pre-print is out! Critical point drying of brain tissue for x-ray phase contrast imaging. @apeart.bsky.social @yuxinzhang.bsky.social @jkbrmn.bsky.social @apacureanu.bsky.social @andreas-t-schaefer.bsky.social @carlesbosch.bsky.social @esrf.fr @crick.ac.uk bioarXiv: doi.org/10.1101/2025...

We are looking for an IT engineer with a focus on operations and research data management at the Centre for Organismal Studies at @uniheidelberg in Heidelberg, Germany #IT #sysadmin #linux #ResearchData please help to spread this opening […] [Original post on biologists.social]

We watched mice follow scent trails drawn on an “endless” treadmill. By manipulating trail geometry/statistics, perturbing mouse nose & brain, and modeling behavior with a Bayesian framework, we show that mice use predictive (rather than reactive) strategies.

And we are off - excited that #cns2025florence is under way with record attendance - first keynote starts in 5 minutes.

Scary. Authors building in hidden instructions for presumed LLM peer reviewers (in white text on white background).

Clinical research in England is wild! 3+ years, 20+ meetings, 200+ documents, 500+ emails is what it can take to open a fully funded, observational non-CTIMP study. Thank you @chrischirp.bsky.social and colleagues for calling attention to this urgent, solvable crisis! www.bmj.com/content/390/...

We wrote a little #NeuroAI piece about in-context learning & neural dynamics vs. continual learning & plasticity, both mechanisms to flexibly adapt to changing environments: arxiv.org/abs/2507.02103 We relate this to non-stationary rule learning tasks with rapid performance jumps. Feedback welcome!

Great thread, showing how even the most educated people need humility to accept what they dont’t know. That’s the way you will learn.

🏊 Serotonin controls how hard a zebrafish swims as changes in its body or environment effect its effort. Now, researchers are uncovering how neurons figure out when & how much serotonin to secrete – providing new insights into neuromodulation ➡️ www.janelia.org/news/new-res...

Tomorrow the second Behavioral Neurobiology Summer School in Collaboration with the Pristina International Summer University will start at University of Pristina, Kosovo!! Thank you Ilir Mazreku for having us over for a visit from Konstanz! Thank you Flutura Shabani for all the organization!

🧵 It's #ResearchAppreciationDay! 🔬 🧪 🧬 Time to shout out our brilliant UCL researchers changing lives daily! Here are just a few of our top research stories of 2025:

Here is your last reminder that the application deadline for Imbizo.Africa is nearing quickly, the 1st of July, in fact tomorrow. Still the place where diversity is at its best in the world! Tell all who need to hear. #africa #neuro

Crick researchers have shown that the ‘pacemaker’ controlling yeast cell division is located inside the nucleus, rather than outside it as was previously thought. This research was led by @nitinkapadia.bsky.social and Paul Nurse. www.crick.ac.uk/news/2025-06...

Researchers at the Crick and UCL have developed laboratory models of dementia, including Alzheimer's, to show that certain genetic messages are misplaced in diseased nerve cells. The finding could offer a potential target for new treatments for neurodegeneration. www.crick.ac.uk/news/2025-06...

ATTN: students & postdocs in #theoreticalneuroscience! Applications are now open for @hhmijanelia.bsky.social's "by the students, for the students" #neurotheory workshop, which will take place Nov. 9 - 14, 2025.

Your nose remembers scents, literally! A new mouse study finds that repeated exposure to certain smells triggers the growth of more neurons tuned to those odours. Over time, this could help fine-tune your sense of smell 👃

10th London Impact Neurotechnology Meeting & King's Surgical Grand Round 📅 June 26th 1730 📍London Institute for Healthcare Engineering 🎟️ Register: lnkd.in/e2ZqU8Pt 🔹 Chair: Mr Jonathan Shapey 🔹Dr Jacques Carolan @jacquescarolan.bsky.social Precision Neurotechnologies 🔹Prof Gail Rosseau, MD

Looking forward to another Impact network meeting on Thursday! www.kingshealthpartners.org/events/khp-a...

🚀🔬🦠 Releasing 🤖Cellpose-SAM🤖, a cellular segmentation algorithm with superhuman generalization 🦸‍♀️. Try it now on 🤗 huggingface.co/spaces/mouse... paper: www.biorxiv.org/content/10.1... w/ @computingnature.bsky.social 1/n

Join us on 1 July as we kick off the #SummerScience Exhibition with a special adults-only Lates evening of science, comedy, and more. Delve into the mysteries of black holes, experience a science-comedy cabaret and much taste themed cocktails at our bar: royalsociety.org/science-even...

A new campaign by the non-profit group Mothers in Science highlights the challenges and experiences that fathers face https://go.nature.com/3TC3QAs

Movie of the week - joined collab of @houartlab.bsky.social & Long lab @kingsioppn.bsky.social @devneuro.bsky.social @crick.ac.uk Joining cell identity to cell behaviour in human embryonic brain. Fascinating >10 days timelapse imaging by @gessicagoncalves.bsky.social A technical tour de force!

Hey all, faculty position here at EMBl Rome closing in 10 days! We looking for people at the intersection of neuroscience and epigenetics (broadly interpreted, totally OK if stronger on one side or another) 1/x embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Today is the festival of music #fetedelamusique in France. 🎶🎼 #DYK that the ESRF contributes to the study and preservation of historical instruments? Now, thanks to the new big sample stage on BM18, the full violin’s family can be scanned, up to the 2m tall double bass.

Are you looking for a job on a research team that is funded by the European Research Council? There are currently 150 of them on the #Euraxess website! 👉 buff.ly/5Ho0qIk Check them out - you might find a great fit for your career! #ChooseEurope #FrontierResearch #AcademicSky

Into population dynamics? Coming to #CNS2025 but not quite ready to head home? Come join us! at the Symposium on "Neural Population Dynamics and Latent Representations"! 🧠 📆 July 10th 📍 Scuola Superiore Sant’Anna, Pisa (and online) 👉 Free registration: neurobridge-tne.github.io #compneuro

New paper in Imaging Neuroscience by Théo Lambert, Alan Urban, et al: Functional ultrasound imaging and neuronal activity: How accurate is the spatiotemporal match? doi.org/10.1162/IMAG...

Hello! I am working on a project with the Royal Institution about the Christmas Lectures, and would love to talk to people who grew up watching them on TV, or now watch them with their own kids (or, ideally, both). Please share 🤗

We’re looking forward to welcoming families to Discovery Day tomorrow 🎉 It’s going to be a hot and sunny day, so please come prepared with hats, sun cream and water. Visit the webpage for more information about the day ⬇️ 🔗 www.crick.ac.uk/whats-on/dis...

Come work in my dept! We are hiring a lecturer in psychology (ideally speaking Dutch) @leidenpsychology.bsky.social www.academictransfer.com/en/jobs/3529...