Jakob Reichmann
@jkbrmn.bsky.social
📤 29
📥 71
📝 5
PostDoc at the Francis Crick Institute. X-ray Imaging x Connectomics.
reposted by
Jakob Reichmann
Carles Bosch
3 months ago
#paper
! X-rays can resolve
#ultrastructure
in tissues non-destructively.
www.nature.com/articles/s41...
Shoutout to key collaborators at
@crick.ac.uk
and
@psich.bsky.social
Ana Diaz,
@adrianawanner.bsky.social
and
@andreas-t-schaefer.bsky.social
, and to the whole team that made this possible.
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Nondestructive X-ray tomography of brain tissue ultrastructure - Nature Methods
Optimizations of X-ray nanotomography including the choice of resin allows high-resolution imaging of mouse brain tissue, approaching the resolution of volume electron microscopy. Since it does not re...
https://www.nature.com/articles/s41592-025-02891-0
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reposted by
Jakob Reichmann
Andreas Schaefer
5 months ago
The Crick is an absolutely amazing place to work in - please share this opportunity widely with your colleagues and postdocs - and DM me if I can help in any way
add a skeleton here at some point
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reposted by
Jakob Reichmann
Carles Bosch
5 months ago
Join us *next Monday*!
#CrickXrays25
X-ray
#nanoimaging
of biological tissues 🇬🇧🌐
@crick.ac.uk
& online
tinyurl.com/crickxrays25
Sponsored by
@dectris.bsky.social
,
@webknossos.org
and
@biologists.bsky.social
and backed by
@brukercorporation.bsky.social
and Histomography
add a skeleton here at some point
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In other news: our Brain Pathology paper is out! We used multiscale
#XPCT
on human FFPE brain to 3D-image Lewy & Hirano bodies, GvD, NFTs, and β-amyloid aggregates at subcellular resolution, quantifying electron density.
doi.org/10.1111/bpa....
@uni-goettingen.de
@esrf.fr
5 months ago
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Excited to co-author work led by
@karlokomorowski.bsky.social
: multiscale XPCT of FFPE human heart-forming organoids at isotropic, subcellular resolution – 3D histology w/o sectioning or staining! 🫀 This opens the door for volumetric histology of complex organoid systems.
doi.org/10.1038/s420...
5 months ago
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reposted by
Jakob Reichmann
Carles Bosch
5 months ago
#Nanoimaging
symposium
@crick.ac.uk
! At
#CrickXrays25
we'll tackle: 💫synchrotron upgrades 📈current limits in throughput, volume, resolution 🧪sample preparation for X-ray PC imaging 🧠♥️applications in neuroscience and tissue life science 🗓️13th October 2025 🇬🇧🌐 London & online
tinyurl.com/crickxrays25
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Hard X-ray imaging of biological soft tissues symposium 2025
https://tinyurl.com/crickxrays25
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reposted by
Jakob Reichmann
Safe Khan
6 months ago
Our pre-print is out! Critical point drying of brain tissue for x-ray phase contrast imaging.
@apeart.bsky.social
@yuxinzhang.bsky.social
@jkbrmn.bsky.social
@apacureanu.bsky.social
@andreas-t-schaefer.bsky.social
@carlesbosch.bsky.social
@esrf.fr
@crick.ac.uk
bioarXiv:
doi.org/10.1101/2025...
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Critical point drying of brain tissue for X-ray phase contrast imaging
X-ray phase contrast tomography is emerging as a powerful method for imaging large volumes of brain tissue at sub-cellular resolution. However, current sample preparation methods are largely inherited...
https://doi.org/10.1101/2025.09.02.673701
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Thanks for featuring!
add a skeleton here at some point
9 months ago
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reposted by
Jakob Reichmann
Yuxin Zhang
10 months ago
My PhD project is out as a preprint! We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals!
doi.org/10.1101/2025...
🙌
@carlesbosch.bsky.social
,
@apacureanu.bsky.social
,
@andreas-t-schaefer.bsky.social
,
@esrf.fr
,
@crick.ac.uk
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reposted by
Jakob Reichmann
PNAS Nexus
about 1 year ago
Using cutting-edge visualization tools, researchers captured a high-resolution, three-dimensional view of the human placenta, an often-overlooked organ upon which every living human once depended. In PNAS Nexus:
academic.oup.com/pnasnexus/ad...
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