We mapped the whole human fallopian tube in 3D and at single-cell resolution via our CODA workflow. More about this work here: biorxiv.org/content/10.1...

Are you studying synapses in electron microscopy? Tired of annotating vesicles? We have the tool for you! SynapseNet implements automatic segmentation and analysis of vesicles and other synaptic structures and has now been published: www.molbiolcell.org/doi/full/10....

Happy to share our latest work led by @kevincziegler.bsky.social and Aydan Askarova, examining cell type contributions of vascular cell types to dementia risk. Many thanks to the donors, and for support from @ukdri.ac.uk and @alzassociation.bsky.social. www.cell.com/neuron/fullt...

Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉 Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life 🔗 journals.biologists.com/dev/issue/15... #FluorescenceFriday #LifelongDevSI

I will give the UCL Prize Lecture in Life and Medical Sciences. If you are in London on December 3, come say hello. Registration is required but free: www.eventbrite.co.uk/e/ucl-prize-...

🧵 BREAKING: Gene therapy shows promise in slowing Huntington’s disease progression. A major milestone in neurodegenerative disease research. @uclqsion.bsky.social @ucl-hd.bsky.social www.bbc.co.uk/news/article...

Dorsal Vagal Complex: A cell atlas to guide research into appetite control buff.ly/QY7ev03

This is why I love science

We are proud to present a Special Issue on Cancer Neuroscience, curated by editors Bennie Babayan & Ted Dobie. This issue offers a snapshot of the field through a collection of Perspectives, Reviews, and NeuroViews: cell.com/neuron/issue.... See below for details on the pieces:

Yesterday.. our #CLEM with Julia Gutjahr and Antal Rot was featured in the main Science webpage....☺️ Nice to see #correlativemicroscopy and #volumeEM up front and centre. www.science.org/doi/10.1126/...

It's a wrap. The Biannual ISRB Meeting has ended. Stay tuned this week as we reflect on exciting science, honour our Lifetime Achievement and Rising Star Awardees and reflect on all we have learnt about regeneration this past week. #ISRB2025

Courtney @courtneyl7a7.bsky.social has written a lovely piece on this wonderful community initiative we’ve been running for 5 years at UCL - have a read! And follow @biig-ucl.bsky.social !

Another beautiful study by the lab of @andyshihlab.bsky.social published today in @natureportfolio.nature.com 👏🏻👏🏻👏🏻 #cerebrovascular #aging

@isrbio.bsky.social #isrb2025 has started and we had a great time at the pre-conference trainee meeting, organised by us, the monthly trainee meeting organisers (Salome Stierli, Grave Schulz, Matt Cherubino, Jackson Griffiths, Carlos Barradas Chacon) - none of them have bsky!

Maybe it's time we rethink the idea that development is a cell centric process? In this beautiful review, María-del-Carmen and @stramerlab.bsky.social discussed how the ECM underlies and influences many morphogenesis processes from wing unfolding to mammary gland development. doi.org/10.1016/j.cd...

Some beautiful Remak cells acquired on the new Hitachi TEM 🤩

I'm deeply honoured to receive the BACR/AstraZeneca Young Scientist Frank Rose Award in recognition of my cancer research. Grateful to @thebacr.bsky.social @astra-zeneca.bsky.social ‬ #Mentors & #Colleagues whose support has shaped this journey. My reflections👇 🔗 www.bacr.org.uk/news/2025-ba...

❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more! www.nature.com/natcardiovas...

Goodbye Alice! Excited for the new one 👀

🚨 SAVE THE DATE 🚨 Inaugural CCP-volumeEM Community Meeting, 3rd November 2025 at @crick.ac.uk in London "Towards a collaborative computational community for volume EM" Timings: 12pm - 5.30pm, followed by networking reception #volumeEM #BioImageAnalysis #VEM #CCPvolumeEM #CoSeC

Exciting next steps in #volumeEM data analysis! A way to remove the data bottleneck..🍾👏 #mmc2025 @ccp-volumeem.bsky.social @martinjones.bsky.social

🎉 Our study identifying the direct precursors of Merkel cells is now published in @dev-journal.bsky.social Thank you to our reviewers @reviewcommons.org and collaborators for helping us improve the manuscript. Check out these cell behaviors we visualized in #zebrafish skin. doi.org/10.1242/dev....

Delighted to share our latest work on the mechanisms of epithelial curvature and 3D morphogenesis ! Amazing work from newly graduated Dr @courtneyl7a7.bsky.social 🎉 @lmcb-ucl.bsky.social @uclnews.bsky.social @ucllifesciences.bsky.social www.sciencedirect.com/science/arti...

Officially PhD! Feeling very lucky to have had such an amazing lab and experience! Thank you to my examiners @stevewilsonfish.bsky.social and Giles Hardingham @ukdri.ac.uk and obviously Alison!!!

New Faraday Fellowships for international applicants moving to the UK Up to £4 million per researcher over 5-10 years Fast-track option for mid-career researchers looking to relocate to the UK

How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵

Pretty amazing graphic to go with the @financialtimes.com article about the cost of Trump's attack on US science NIH is HUGE! www.ft.com/content/67fd...

Our May issue is now live! www.nature.com/neuro/volume...

For those who want a distraction and/ or are interested, here's the latest from the group, led by Phil Braaker www.nature.com/articles/s41...

The feeling of a hug comes from the pressure and vibration of millions of nerve endings.

I’ve submitted but not quite done it yet! The viva is on 3rd of June at the @lmcb-ucl.bsky.social 😎 thank you so much for the cake 🫶🏻 @stellakouloulia.bsky.social & Delan who is still not on bluesky

Delighted to share our latest work deciphering the landscape of chromatin accessibility and modeling the DNA sequence syntax rules underlying gene regulation during human fetal development! www.biorxiv.org/content/10.1... Read on for more: 🧵 1/16 #GeneReg 🧬🖥️

🧵 🧪 1/ Female #ReproductiveBiology is, unfortunately, notoriously understudied. So maybe it’s no surprise that a supposedly useless ‘developmental leftover’ in the ovaries could turn out to be...not so useless after all. Meet the rete ovarii 👇 buff.ly/VudxQ2U

REPOSTING this here just to officially leave "the other place" Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social nature.com/articles/s41...

@LukeNoon from CIPF shared insights into his research at the vEM Data Challenges Symposium on mapping liver & peripheral tissues using innovative annotation & collaboration strategies. 🎥 Watch the recorded session here: youtu.be/1sMQFpRGMLs?....

Detailed charts of fetal hearts Read this Research Highlight showcasing work from Christopher De Bono, Stéphane Zaffran, Heather Etchevers @etche.bsky.social & colleagues: journals.biologists.com/dev/article/...

Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...

Let's talk about this Nature piece in more detail. I've rarely read something so anti-scientific anywhere short of the National Review. www.nature.com/articles/d41...

Dream Catcher

Newest paper from the Lloyd Lab 👏🏼 www.cell.com/cell-reports...

"Imagine a DAPI-like stain, but for the extracellular matrix." That's basically how this work was pitched to me by Kayvon and Antonio a year or so ago. Now the final product really delivers. Read about their versatile label for ECM in living tissues here: www.nature.com/articles/s41...

In 2019, the #mesoSPIM and #ctASLM #lightsheet #Microscopy papers appeared back-to-back in @naturemethods.bsky.social - now Jinlong Lin, @zacsimile.bsky.social & @kevin-dean.bsky.social & Co introduce the MCT-ASLM - a chimera of both for smart multiscale #imaging! www.biorxiv.org/content/10.1...

JCS Editor-in-Chief @drmichaelway.bsky.social introduces our new Associate Editors. We are delighted to welcome Sophie Acton @actonlab.bsky.social, Pedro Carvalho, @guijacquemet.bsky.social, @ckirchhelle.bsky.social and Aryeh Warmflash to the JCS team. journals.biologists.com/jcs/article/...

In fairness, “you can make millions of individual molecules but there are 13 that you need but can’t make so let’s outsource their production to plants. Also, it’s actually 12…you can make one of the vitamins…as long as the sun’s rays touch your skin like you yourself are a plant” does sound fake.

Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal -synapse number and maturation -seizure susceptibility and hippocampal-prefrontal cortex coherence -segregation of inputs into the lateral geniculate nucleus -neuronal and astrocytic gene expression www.nature.com/articles/s41...

Happy last #FluorescenceFriday before Xmas! It's been a long, stressful 2024 that ended on a high with news of 3 successful grants. Nearly time to rest, relax & regroup before an exciting 2025. Enjoy this beautiful quail neural tube & somites imaged by talented undergrad Avelynn Ang Xin Li 😍🧪#devbio