Seeking work in a research group run by an ERC-funded researcher? You can find more than 145 positions open for application on the #Euraxess website 👉 europa.eu/!gdXPfd #ChooseEurope #jobs #research

Excited to share our new Nature paper published today: Vaccination elicits HIV broadly neutralizing antibodies in primates www.nature.com/articles/s41... A project 14 years in the making with an outstanding team at @lji.bsky.social, @scrippsresearch.bsky.social and many collaborating institutions

Uganda has not yet confirmed it publicly, but it appears to have a #Marburg outbreak. A very reliable source tells STAT that 2 cases have been confirmed. The US government has issued a level 4 — aka do not travel there — advisory based on intel it has received. www.statnews.com/2026/06/30/m...

Faculty search announcement 2026: Tenure-Track Assistant Professor in Microbiology at UT Southwestern in Dallas. We seek candidates working in microbial pathogenesis (broadly defined). Come join our community! (1/5) www.utsouthwestern.edu/departments/...

New in @nature.com: Preclinical trial led by La Jolla Institute and Scripps Research scientists shows that new #HIV vaccine yields high numbers of protective antibodies in non-human primates: www.nature.com/articles/s41... #Health #Medicine #Virology #Vaccines @profshanecrotty.bsky.social

Incredibly proud of Messi Haile @mehsehret.bsky.social, a founding member of the Ho Lab, for her beautiful work uncovering the inner workings of a central piece of the malaria parasite invasion machinery: the malarial moving junction, out today in @cellpress.bsky.social! tinyurl.com/4p3md2eb 🦠❄️🔬

WHO has released its first-ever set of comprehensive guidelines for the clinical management of filovirus disease which include all Ebola and Marburg diseases. 🔗 bit.ly/4uELsqY

Cryo-ET is often framed as a tool for in situ protein structure. But what if the real revolution is contextualization? I explore how #teamtomo is redefining what "local" means in organelle biology, revealing membrane states rather than just protein structures. tinyurl.com/localmembrane

In case you missed it last year, I reviewed how the advances in segmentation and model extraction make many of these insights possible. Before we can understand local membrane environments, we need methods to convert tomograms into quantitative models of cellular landscapes. tinyurl.com/quantmodels

Great, very promising findings! www.biorxiv.org/content/10.6...

“the best way to work with cryoET data is to engage with it directly, […] build familiarity with what is actually there. As tempting as it sometimes is to lean in to automation entirely, we cannot do visual proteomics by relying blindly on automation.” mgflast.github.io/easymode/use...

We're happy to announce our new preprint! 🐸 easymode: general pretrained networks for cellular cryo-ET. Segment ~20 cellular features – ribosomes, microtubules, mitochondria, nuclei & more – with zero model training. 🔗 doi.org/10.64898/202... 🧵👇

Why do influenza viruses make ludicrously long filamentous virions? Probably lots of reasons, but in a new study Lu Liu et al. provide evidence for an appealing hypothesis: filaments are more stable in acidic solutions and hence survive for longer in aerosols www.nature.com/articles/s41...

📢 ¡Anunciamos el Simposio "The Structure and Working of Molecular Machines" Más información en: biophysal.org/symposium/ #BioPhySal #SomosLUMES #USAL #MolecularMachines @usaloficial.bsky.social @ibfg.bsky.social @csiccyl.bsky.social @ciccancer.bsky.social @irnasa.bsky.social

In issue 10: Convergent evolution of aerobic fermentation CIN promotes migration & invasion via EFEMP1 secretion SenSet resource defines cell-type specific senescence signatures ... Cover: @franbottanelli.bsky.social and colleagues link.springer.com/journal/4431...

📢 Cryo Lift-Out commissioning call now open (eBIC) 🗓 Apply by 05 Aug 2026 for experimental access Oct 2026 – Apr 2027 ⚙️ Aquilos CryoFIB @diamondlightsource.bsky.social 🎥 Join our webinar for more info + ask questions 👇 🗓 22 May | 11:00 BST 🔗 bit.ly/cryo-Lift-Out 🔐 498563 #CryoEM #CryoET #CryoFIB

I’ve been trying to understand what we know and don’t know so far about the concerning Ebola outbreak in DRC. Still lots of uncertainty at the moment but here‘s what I have been able to find out so far. Story is here (thread coming later): www.science.org/content/arti...

🔴 Transmission is particularly amplified in health-care settings when infection prevention and control measures are inadequate, and during unsafe burial practices involving direct contact with the deceased. More bit.ly/43cOnM2 #Ebola

Congo’s New Ebola Outbreak Has No Vaccine, No Treatment, and Has Already Crossed a Border Bundibugyo ebolavirus confirmed in Congo and Uganda. The world has no approved countermeasures for it. Read & subscribe (for free!) www.celinegounder.com/p/ebola-bund...

The abstract deadline for the FASEB Virus Structure and Assembly Conference is approaching - May 25! Join us for an exciting meeting on structural virology, virus assembly, RNA biology, and antiviral therapeutics. We look forward to seeing you there! #FASEB #Virology #StructuralBiology #CryoEM

LJI Professor, President & CEO Erica Ollmann Saphire, Ph.D., talks #measles AND big steps her lab has taken in developing a measles treatment: youtu.be/oy8xnsSb4U0?... #ImmuneSystem #Immunology #Virology #Viruses #Health #Medicine #SanDiego

Super interesting finding: The virus shape also influences stability in aerosols! rdcu.be/fiZA8

Applications and prospects of cryo-electron tomography in drug discovery and understanding disease Review article by @camilaclemente.bsky.social in our lab www.sciencedirect.com/science/arti...

New Ebola outbreak in Ituri, DRC, with 65 reported deaths, so far. My heart goes out to people there, already suffering from deadly attacks on civilians. www.aljazeera.com/news/2026/5/... Ebola could spread because of people displaced from conflict, says #AfricaCDC. africacdc.org/news-item/af...

For 40 years the 8-nt ‘Kozak Sequence’ was thought to mark sites of translation initiation. In a new study, we revise this model by identifying an ~80-nt sequence—the extended Translation Initiation Sequence (eTIS)— that guides ribosomes to correct start sites. 🧵 www.biorxiv.org/content/10.6...

Wow - this is just amazing. Hui Guo and colleagues from John Briggs’ lab use cryoEM helical reconstruction to discover how filamentous influenza virion assembly is directed by multiple conformations of M1 - explaining how NA is concentrated at the proximal pole. www.biorxiv.org/content/10.6...

Presser on #hantavirus happening now: www.youtube.com/live/ksOTrl0...

We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better. Preprint: www.biorxiv.org/content/10.6... Code: github.com/warpem/miss-... 🧶 Thread:

1) The Herzik lab is excited to announce our newest preprint in collaboration with the Grotjahn lab! We have developed a surfactant cocktail that seeks to overcome one of the more nefarious problems in #cryoEM, Air-water interface (AWI)-induced damage and preferred orientation (PO).

Looking forward to the guest lecture of Prof. Nikolaus Grigorieff from the University of Massachusetts about “Extending the scope of single-particle cryo-EM using 2D template matching” on March 23 at 12:30 in seminar room N100/114. Remote access: uni-frankfurt.zoom.us/meeting/regi...

We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo. #OpenSoftwareAcceleratesScience

I've written a review on what I think is an extremely exciting direction in cryo-EM: Cryo-EM of endogenous membrane proteins in their native lipid bilayer Open access in Quarterly Reviews of Biophysics: doi.org/10.1017/S003...

We found a viral Trojan Horse: a virus can hide inside another virus.This one surprised us: deltaviruses don’t just borrow a helper virus. They can travel inside it. A literal Trojan Horse “virus-in-a-virus” route into cells. 🤯 Kudos to 1st author @viroscope.bsky.social and co-authors !

A research team from the Max Planck Institute for Multidisciplinary Sciences, the Institut Pasteur, and EMBL has shown in a Nature paper how the influenza polymerase, a molecular thief, uses the host RNA to replicate. Check out the MPI press release: www.mpinat.mpg.de/5179649/pr_2...

Apply now! @vbcscitraining.bsky.social offers more than 25 fully-funded PhD positions! GMI group leaders are also recruiting new students.

𝗘𝘅𝗰𝗶𝘁𝗶𝗻𝗴 𝗗𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁𝘀 𝗶𝗻 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆 𝗥𝗲𝗽𝗼𝗿𝘁𝗶𝗻𝗴! If you're involved in creating, processing, or publishing microscopy data, take a look at the new checklist for reporting requirements provided by @quarep-limi.bsky.social in @jcb.org 🔗 rupress.org/jcb/article/...

This immunogen is cheap and easy to produce and elicits a high quality antibody response. Project led by @nawsadalam. Read all about it: link.springer.com/article/10.1...

We have started a project trying to predic the interactions/structures of all yeast protein pairs using an AlphaFold pooling approach. We are making the current dataset open and we welcome collaborations. www.evocellnet.com/2026/03/mapp...

The new Vienna BioCenter Interdisciplinary Postdoctoral Program (VIP³) is here! We have 8 fully-funded positions for scientists with a PhD in biology, chemistry, physics, bioinformatics etc. The call is open! More information: training.vbc.ac.at/post-docs/vi... #VBCPostDoc

Now online! High-resolution in situ structures of hantavirus glycoprotein tetramers

The new ChimeraX CubeNTube plugin allows erasing parts of maps using cube, cylinder, and custom shapes and has undo. Created by Tamino Cairoli. Available from ChimeraX menu Tools / More Tools....

Study from a team of Canadian and German researchers has uncovered never-before-seen details about what happens to proteasomes, the cell’s garbage disposal system, when there is not enough energy. bit.ly/3OGywRX

Your airways and your gut are high-traffic areas for the microbes of the world. 🦠 For more than 40 years, LJI's Mitchell Kronenberg has studied the T cells that step up to defend our most vulnerable organs. Now Kronenberg has been elected fellow of the AAM: bit.ly/4rBrcps @asm.org #microbiology

“Compared to the reduction at the national level, the large declines in cervical cancer incidence observed in several states were very encouraging" Cancer rates decreased in states with the highest HPV vaccination rates - #MedSky + #OncSky + #ReproSky. pressroom.cancer.org/declines-in-...

Nice #alphafold

Tried it. Its awesome. Shame the code isn't available. Webserver only, how long will it last??

Long in the making, but happy to present the Chlamydomonas chlororibosome! Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins. bioRxiv 📖: shorturl.at/q44tG This suggests greater chlororibosome diversity than expected! 1/n 🧵

I've been working on Surface Morphometrics for a new version (coming soon), and made some significant (AI-assisted) performance improvements, especially in pycurv (20-50x!). If you've had technical issues or just felt like it was too slow, give it another try! #teamtomo github.com/GrotjahnLab/...

🚀 CryoSPARC v5.0 BETA is here! We’re excited to deploy another major #CryoSPARC release to help enable and accelerate #cryoEM data analysis. v5 has a redesigned underlying software system and many new features - highlights in thread! Full changelog: cryosparc.com/updates/v5.0.0