Understanding geometry through model making

Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis. Learn more this week: https://scim.ag/4nFEGO7

🚨Curious how synthetic fluorophores simplify microscopy? Our review covers applications such as super-resolution microscopy and biosensing. 🎉👩‍🔬Congrats to my first PhD student, Agnese Nicoli, for the fearless deep dive! 🔬 ⚗️ D-CHAB @ethz.ch www.nature.com/articles/s41...

Glushkova, Böhm, & Beck @maxplanck.de develop a publicly available computational method to measure the thickness of biological membranes in cryo-electron tomograms. Analysis of algae & human cells reveals systematic membrane thickness variations within & across organelles rupress.org/jcb/article/...

*If you would like to be considered for a talk at this workshop, please register & submit an abstract by 7 November* We also have a fantastic line-up of invited speakers: Matteo Degiacomi, Lucie Delemotte, Weria Pezeshkian, Mohsen Sadeghi & Ilpo Vattulainen Registration: aias.au.dk/events/show/...

Localization of the #septin #cytoskeleton is controlled by regulatory factors, membrane curvature, & charge. In this study, @gladfelterlab.bsky.social finds changes to #lipid composition that modulate lipid packing defects to impact septin assemblies in vitro & in cells. rupress.org/jcb/article/...

🔬 CECAM Workshop: “Integrative and Multiscale Modelling Approaches to Illuminate CryoEM/ET Data” Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data. 🧬 Selection: brief CV + motivation letter required. Apply 👇

MD community, do you want to help designing new tools for MD data search. Please sign up! 👇

#compchem #machinelearning #quantumcomputing We have several open positions & we are looking for: - 2 postdocs in machine learning to work on foundation models (theoretical developments) - 2 HPC engineers: quantum computing(1); ab initio computations and QM/MM (2) Reach to me for more details.

#ACSChemBio and #Biochemistry invite submissions to a special issue on Lipids and Lipidation guest edited by @chembiobryan.bsky.social and me! Find details in the #CallforPapers and submit your exciting findings to one of these journals by May 31, 2026. axial.acs.org/chemical-bio... #lipidtime

Passionate about GPCRs and molecular pharmacology? We’re looking for a PDRA to use computational molecular modelling and in vitro approaches (BRET etc) to uncover how the nitazene classe of synthetic opioids work. Learn more and apply: www.bristol.ac.uk/jobs/find/de... Reposts appreciated!

Physics-based evolution of transmembrane helices reveals mechanisms of cholesterol attraction www.nature.com/articles/s41...

Back to Oxford!

🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...

Do you want to invent the future of Chemistry with us? We‘re looking for a "Digital Native” Organic Chemist to join our team at Microsoft Research AI for Science. We offer an amazing environment where you can do deep research with passionate and talented colleagues to solve problems that matter! 1/2

The 3rd Annual Danish Workshop on Advanced Molecular Simulation. This time in Aarhus

Happy to finally see The Lipid Brain Atlas out! Lipids are not boring at all so, check it out! Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it. Lipids rule!

Happy to be at the @cecamevents.bsky.social workshop on "When data science meets molecular dynamics" We will have three days of interedting and lively discussions!! Thank Adam, Eril, and Modesto for the invitation.

Bacterial cell envelope-targeting antibiotics | Nature Reviews Microbiology https://www.nature.com/articles/s41579-025-01247-x

Thanks to @snsf.ch, we are hiring two PhD students to investigate frontier topics in lipid biology using a combination of MD simulations and experiments. Preferred starting date: ASAP. Fribourg - and Switzerland - are quite nice, for both work and private life! Please spread the word!

5 million of them are about research

Our collaborative work with W Im lab is now published as V1 in @elife.bsky.social alongside with reviewers comments. We will update this version to answer to reviewers comment but we believe that this version is already a good start to understand mycomembrane structure! doi.org/10.7554/eLif...

Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11) 🔗 www.biorxiv.org/content/10.1...

Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026. Deadline: 20 December 2025 https://meetings.embo.org/event/26-cytoskeleton#cytoskeleton#research#EMBOCytoskeletalFunction #EMBOevents #conference 🧪

#molstar now supports immersive AR/VR - enjoy molstar.org/xr/

Cardiolipin dynamics promote membrane remodeling by mitochondrial OPA1 www.nature.com/articles/s41...

Integrative modelling of biomolecular dynamics Time-dependent and -resolved experiments combined with computation provide a view on molecular dynamics beyond that available from static, ensemble-averaged experiments Review w @dariagusew.bsky.social & Carl G Henning Hansen doi.org/10.48550/arX...

Join our BioEmu project @msftresearch.bsky.social AI for Science. In Berlin DE or Cambridge UK: aka.ms/bioemu-ml - #MachineLearning Researcher aka.ms/bioemu-data - Data Engineer aka.ms/bioemu-applied - Applied Researcher aka.ms/bioemu-principal - Principal Applied Researcher

The students of the Computational Biology M.Sc. of Paris-Saclay (AMI2B) organize the Junior Conference on Computational Biology (JC2B) that will be held on November 13, 2025 at I2BC CNRS, Gif-sur-Yvette. The call for contributions is open until October 20 2025: bioi2.i2bc.paris-saclay.fr/jc2b/

Rigorous and creative work showing a novel way to think about protein-lipid interactions.

Postdoc position available in the BioEmu team at @msftresearch.bsky.social AI for Science - Berlin DE or Cambridge UK. Looking for candidates with backgrounds in #MachineLearning #AI Biophysics or Bioinformatics jobs.careers.microsoft.com/global/en/jo...

Ever wondered how to position organelles in bacteria? Wonder no more! Happy to have contributed to this fantastic story from @cellforganized.bsky.social' lab. The avenues this opens in the synthetic biology space are enormous! Movie: Carboxysomes positioned in E. coli! Preprint: shorturl.at/D6xVg

A great feature in @science.org on the recent LLM Hackathon in Berlin highlights how coding, collaboration, and FAIR data go hand in hand for accelerating materials discovery. Read more in the article by Zack Savitsky ⬇️ www.science.org/content/arti...

'At the Scripps Research Institute, (...) we created the Computational Biology and Bioinformatics (CBB) affinity group, a trainee-led community for the discussion of computational biology/bioinformatics with the goal of facilitating knowledge exchange.'

A new preprint from my group by my PhD student Adria: No attraction between proteins, they do not induce curvature, but they cluster on membranes. One of the reasons why mesoscale modeling matters. www.biorxiv.org/content/10.1...

New review on computational design of intrinsically disordered proteins 🖥️🍝 by @giuliotesei.bsky.social @fpesce.bsky.social & 👴 doi.org/10.48550/arX...

Stability vs flexibility: reshaping archaeal membranes in silico This ‘fundamental’ study characterises the mechanics and stability of bolalipids from archaeal membranes using a minimalist, physics-based computational model. buff.ly/jCnRfkO

Very excited to share new work out today in @natchembio.nature.com on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n) www.nature.com/articles/s41...

🔬 MD community call! 🧪 Join us for the “Learn • Connect • Innovate” Co-Designing Workshop Series, part of the @lumen-eu.bsky.social project to shape the future of open science tools, workflows, and collaboration across disciplines. lumenproject.eu/learn-connec...

The latest @livecomsjournal.bsky.social tutorial "Molecular Dynamics: From Basics to Application" by Vollmers, Chen et al is out now! doi.org/10.33011/liv... It includes comprehensive MD tutorials in GROMACS, covering forcefields, thermodynamic ensembles, long-range electrostatics and much more!

This is an really amazing opportunity. If you get it, you can essentially pick you institute. The package really is rather competitive.

We're hiring! Join our team at @fau.de ! We are seeking an enthusiastic candidate for a PhD position in our lab specializing in cutting-edge theoretical and computational membrane biophysics. Please send your CV, and a statement of research interests via email. www.biomemphys.nat.fau.de/jobs/

The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand. Learn more in a new #SciencePerspective: https://scim.ag/45GWQrS

📢 We are hiring #PhD students and #Postdocs at the @mpi-nat.bsky.social in in the Department of Theoretical and Computational #Biophysics in Göttingen 🇩🇪! 🔗 check our current job adverts at www.mpinat.mpg.de/grubmueller and find your project. Submit your #application today! #job

our article "How PGL finds a sweet spot in phospholipid membranes: A combined multiscale MD and NMR study" is now freely available in its final version in @biophysj.bsky.social www.sciencedirect.com/science/arti...

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators. www.nature.com/articles/s41...

Spread the word - we at @stanford-chemh.bsky.social are searching to fill a new junior faculty at the interface of molecular and computational science. See link below!

27 simulations of capturing hundreds of lipid scrambling events reveal mechanisms of lipid translocation. However, according to reviewers, more evidence is needed on outside-the-groove scramblase activity. buff.ly/sVdXMyM

Luciano, M., Tomba, C., Roux, A., & Gabriele, S. (2024). How multiscale curvature couples forces to cellular functions. Nature Reviews Physics, #EpithelialMechanicsReview www.nature.com/articles/s42...

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...