Südtirol/Alto Adige. Strudelkopf/Monte Specie (2307). 📷Canon EOS 5 🔘70-300 mm 🎞️Ilford HP5+ #BelieveInFilm #Dolomiti

"World's first potential trillionaire has killed 600,000 people, including 400,000 children" is the only headline that anyone should ever read about Elon Musk

Sweet new #glycotime science out of the Huang lab looking at roles of glyco in the placenta.🧪🧪

Kolka, Latvia. 📷Canon EOS 5 🔘70-300 mm 🎞️Ilford HP5+ #BelieveInFilm

What happens if your asexual reproduction goes wrong? For instance, you can grow a head instead of a tail. But if you're a flatworm, it's not that bad - as we showed in our newest paper published in the Proceedings of the Royal Society B: tinyurl.com/4dnp2ffz

Oviši, Latvia. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford HP5+ #BelieveInFilm

Another great paper from @jeffcolgren.bsky.social and @pawelburkhardt.bsky.social. Must-read for everyone interested in the evolution of neurons! #neuroscience

Tahkuna, Hiiumaa Island, Estonia. Memorial to the victims of the Estonia ferry disaster, which took the lives of 852 people in 1994. 📷Minolta X-300 🔘28 mm 🎞️Ilford FP4+ #BelieveInFilm

Kuldīga, Latvia. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford Delta 400 #BelieveInFilm #turpism

Vilnius, Rasų kapinės/Wilno, cmentarz na Rossie. 📷Bronica ETRS 🔘150 mm 🎞️Ilford Delta 100 #BelieveInFilm

Interesting review from Richard Cummings lab about N- and O-glycosylation of brain cell surface glycoproteins. Role in brain development and neuronal functions, spatial distribution, CDG. Must-read! tinyurl.com/ybbnb4x6 #glycotime

Loss of O-GlcNAcylation in cardiac myocytes triggers the integrated stress response contributing to heart failure tinyurl.com/58m9ruyc #glycotime

Kolka, Latvia. View on the Gulf of Riga. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford HP5+ #BelieveInFilm #turpism

Kolka, Latvia. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford HP5+ #BelieveInFilm

Kuldīga, Latvia. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford Delta 400 #BelieveInFilm

Asparagine-linked glycosylation protein 1 (ALG1) in lung cancer progression: it promotes lung cancer aggressiveness through the regulation of protein glycosylation and modulation of ER-stress pathways. Role of EGFR-mediated signalling discussed. tinyurl.com/yt3vxxnk #glycotime

Ventspils, Latvia. 📷Minolta XD7 🔘28 mm + orange filter 🎞️Ilford FP4+ #BelieveInFilm #Latvia

Why do cancer therapies often fail? Leon Strzadala proposes a novel therapeutic approach that includes dismantling of the tumor microenvironment adaptations (e.g. hypoxia), inhibiting oncogenic Ras signaling and restoring p53 activity. tinyurl.com/55af4p2z #cancer #therapy

A dual fluorescent-Raman bioorthogonal probe for specific biosynthetic labeling of intracellular gangliosides can differentiate between cells that differ in ganglioside biosynthetic flux, e.g. malignant and nonmalignant cells. tinyurl.com/xenhuk3v #glycotime

BREAKING: Scientists Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi win the 2025 Nobel Prize in Physiology or Medicine for 'their discoveries concerning peripheral immune tolerance' reut.rs/4gVXo2d

Paczków, Kościelna Street. 📷Minolta XD7 🔘28 mm 🎞️Ilford FP4+ #BelieveInFilm #turpism

P. pastoris expression of two α1,2-fucosyltransferase genes from the Pacific oyster (Crassostrea gigas): antigenic similarity to human FUT1 and FUT2. Role in norovirus transmission discussed. tinyurl.com/5yh2aysn #glycotime

A solemn day as we pay our respects to Dr Jane Goodall and her extraordinary legacy. Vale, Jane, we promise to keep fighting for all that you loved and fought for too! theconversation.com/only-if-we-h... With @drkyliesoanes.bsky.social, Marissa Parrott, @drvanessapirotta.bsky.social & Zara Bending.

Kolka, Latvia. Evangelical cemetery. 📷Bronica ETRS 🔘150 mm 🎞️Ilford FP4+ #BelieveInFilm

Phage receptor binding protein and Fc fragment fusion enhances phagocytosis of Yersinia enterocolitica. Role of N-glycans evaluated. tinyurl.com/4r6dakf9 #glycotime

Please consider signing a petition to increase the spending on science in Poland / List otwarty w sprawie finansowania nauki, w tym @ncn.gov.pl www.petycjeonline.com/list_otwarty...

Glycoproteins, glycolipids, or both: why do glycosyltransferases recognize different acceptors? The final version of the review by @kmikolajczyk.bsky.social @rkaczmarekdr.bsky.social is out! tinyurl.com/5b6kxhp3 #glycotime

Vilnius, Rasų Cemetery. Wilno, cmentarz na Rossie. 📷Bronica ETRS 🔘150 mm 🎞️Ilford HP5+ #BelieveInFilm

Why is there only one O-GlcNAc transferase (OGT)? A review in JBC suggests that OGT is a sensor of various biological stimuli, responding by undergoing post-transl. modifications or through its short linear motifs that alter its activity, subcellular localization and stability. tinyurl.com/27h2fm9r

Interesting review about the role of glycans in neuroinflammation: mechanisms, implications, and therapeutic strategies for neurodegenerative diseases. Alzheimer’s disease, Parkinson’s disease, multiple sclerosis and amyotrophic lateral sclerosis. tinyurl.com/44hpe8ud #glycotime

Kolka Cap, Latvia. 📷Bronica ETRS 🔘50 mm 🎞️Ilford FP4+ #BelieveInFilm #Latvia

Pāce, Latvia, evangelical cemetery. 📷Bronica ETRS 🔘150 mm 🎞️Ilford FP4+ #BelieveInFilm

How ABO blood group antigens influence the risk of early spontaneous preterm birth (sPTB)? Cervicovaginal fluid contains ABH glycans that bind to key vaginal bacteria. The highest risk of sPTB among B-group individuals? tinyurl.com/28mjv2va #glycotime

Stralsund, Old City. 📷Minolta X-300 🔘28 mm 🎞️Ilford FP4+ #BelieveInFilm

Warsaw, Piwna Street. 📷Minolta X-300 🔘28 mm 🎞️Ilford FP4+ #BelieveInFilm

Brzeg Dolny, Odra River. 📷Minolta X-300 🔘70-210 mm 🎞️Ilford FP4+ #BelieveInFilm

Wrocław, Rydygiera Street. 📷Minolta X-300 🔘28 mm 🎞️Ilford FP4+ #BelieveInFilm #turpism

Wrocław and the A8 highway bridge seen from Maślickie Hill. 📷Minolta XD7 🔘70-210 mm 🎞️Ilford FDP4+ #BelieveInFilm

big one! a decade in the making. nadler & team develop tools to track lipid transport in living cells at single-species resolution. turns out non-vesicular, asymmetry-driven transport is the main architect of organelle identity. feels like the dawn of a golden era for lipid biology. rdcu.be/eBGJv

Nice review about the role of the O-GlcNAcylation in regulating the cell cycle in cancer and its involvement in the PI3/K-Akt pathway as a promoter of the cell cycle progression. Novel cancer therapies proposed. tinyurl.com/3fpaxe2k #glycotime

The pros and cons of Trichoplusia ni insect cells (High Five) and human embryonic kidney cells (Expi293F) as the expression hosts for glycosylated proteins. Location of the His-tag also evaluated. tinyurl.com/2xkmxtet #glycotime

Wolsztyn, steam engine museum. Ol49-69 with the train Wolsztyn-Poznań. 📷MinoltaXD7 🔘28 mm 🎞️Ilford FP4+ #BelieveInFilm

Opole power station seen from Lipowa Street in Opole-Gosławice. 📷Minolta XD7 🔘135 mm 🎞️Ilford FP4+. #BelieveInFilm #turpism

Wrocław, World War I Italian Cemetery. 📷Minolta X-300 🔘135 mm 🎞️Ilford FP4+ #BelieveInFilm

Interesting! Lacritin, the major protein of human tears, is heavily glycosylated with 19 O-glycosites and many O-glycan structures. Alphafold 3.0, with PTMs and GlycoShape, shows (albeit differently) how O-glycans influence the structure. Tear glycome also analyzed. tinyurl.com/ycxyxehe #glycotime

Paczków, Opolskie voivodship. City walls from the 16th Century. 📷Minolta XD7 🔘28 mm 🎞️Ilford FP4+ #BeliveInFilm

Nysa, Opolskie voivodeship. Market Square with St. James' church and Józef Piłsudski monument. 📷Minolta XD7 🔘28 mm + orange filter 🎞️Ilford FP4+ #BelieveInFilm

Ctenophores possess a unique aboral organ that acts as a multisensory center, controlling complex behaviors. We’ve now created a ctenophore model integrated with our 3D volume EM data. Puts it into perspective. Check out our recent work here: www.biorxiv.org/content/10.1... #ctenophores #volumeEM

Now this is big! N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs by blocking the hypermodified uracil base acp3U (which is immunostimulatory), thus pereventing RNAs from inducing acp3U-dependent innate immune activation. tinyurl.com/mrxaja37 #glycotime

Exploring glycoform-dependent dynamic modulations in human immunoglobulin G by computational/experimental approaches: the absence of Gal enhances the mobility of the glycan and the CH2 domain; Fuc influences the Fcγ receptor IIIa binding. tinyurl.com/2y4dcdpt #glycotime