Marcin Czerwinski
@czerwinsmarcin.bsky.social
📤 1062
📥 1153
📝 620
Researcher | glycobiology | blood groups | enviroment | photography digital and analog | Poland
Oś, Opolskie voivodeship. Evangelical cemetery. 📷Minolta XD7 🔘135 mm 🎞️Ilford FP4+
#BelieveInFilm
about 13 hours ago
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Wrocław, World War II Cemetery. 📷Bronica ETRS 🔘150 mm 🎞️Ilford FP4+
#BelieveInFilm
4 days ago
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reposted by
Marcin Czerwinski
Tomasz Markiewka
6 days ago
Jeśli zmęczyły was promocyjne gadki szefów Big Tech, jak ich innowacje zmienią wszystko na lepsze, mam dla was dobrą i złą wiadomość. Dobra: takich gadek jest coraz mniej. Zła: zastąpiło je przekonywanie, że musimy pogodzić się ze zmianami na gorsze.
krytykapolityczna.pl/swiat/ai-pos...
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Muskizm: futuryzm w służbie plutokracji • Krytyka Polityczna
Postęp techniczny nie oznacza już poprawy warunków życia większości ludzi. Bossowie od AI zapowiadają otwarcie: będzie wam wszystkim gorzej.
https://krytykapolityczna.pl/swiat/ai-postep-rewolucja-ideowa-plutokracja-musk-thiel-panstwo-dobrobytu/
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Moje uwagi na temat książki Anny Wacławik i Marii Ciesielskiej "Fleck. Ocalony przez naukę". Wyjaśniam, co odkrył Ludwik Fleck i dlaczego jest to ważna postać.
tinyurl.com/53bd6tfd
6 days ago
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Z okazji 20. rocznicy śmierci Stanisława Lema, Piotr Gociek rozmawia z Markiem Oramusem. Bardzo ciekawe!
www.youtube.com/watch?v=CG6o...
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Jaki był Lem prywatnie? Co go inspirowało? Czy znasz sekrety autora Solaris?
YouTube video by Piotr Gociek zaprasza
https://www.youtube.com/watch?v=CG6o4HzjZ3E
8 days ago
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Domasłów, Kępno county, Poland. 📷Minolta XD7 🔘28 mm 🎞️Ilford FP4+
#BelieveInFilm
#Turpism
9 days ago
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Harjumaa, Estonia. Abandoned Soviet military base. 📷Minolta X-300 🔘28 mm 🎞️Ilford FP4+
#BelieveInFilm
#turpism
11 days ago
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This is big!
add a skeleton here at some point
12 days ago
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@rkaczmarekdr.bsky.social
commentary about the role of neutralizing anti-AAV antibodies (NAbs) in hemophilia B therapy.
www.rpthjournal.org/article/S247...
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Hemophilia B gene therapy: a NAb-solute barrier overcome by AAV5
https://www.rpthjournal.org/article/S2475-0379%2826%2900086-5/fulltext
12 days ago
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reposted by
Marcin Czerwinski
Chris Ashwood
20 days ago
Engineered OAA lectins as selective and sensitive high mannose glycan targeting tools - Uses LC-MS as a readout for pulldowns from these anti-glycan reagents.
www.biorxiv.org/content/10.6...
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Polecam wywiad prof. Dariusza Jemielniaka z prof. Victorem Ambrosem, jednym z odkrywców mikroRNA i laureatem Nagrody Nobla w 2024 r.
academia.pan.pl/victor-ambro...
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Victor Ambros i Dariusz Jemielniak o RNA, dezinformacji i zaufaniu do nauki - Academia PAN
Pandemia pokazała, jak potężnym narzędziem jest współczesna biologia. Pokazała też, jak łatwo nauka staje się celem dezinformacji. O szczepionkach mRNA, propagandzie i potrzebie lepszej komunikacji na...
https://academia.pan.pl/victor-ambros-i-dariusz-jemielniak-o-rna-dezinformacji-i-zaufaniu-do-nauki/
20 days ago
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Interesting review about core fucose, its molecular targets and functions in inflammatory signaling pathways
tinyurl.com/3yu3henn
#glycotime
20 days ago
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In a letter to the Editor of Glycoconjgate J., Amit Ranjan and Rajesh K. Gupta discuss the outstanding questions regarding glyco-RNA biology, and explain why new tools for accurate detection and characterization of glycans of glycosylated RNAs are so important.
tinyurl.com/bd94nw2e
#glycotime
21 days ago
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Another great study from
@drmpblakeley.bsky.social
@anneimb.bsky.social
: neutron macromolecular crystallography (NMX) of a lectin from P. aeruginosa reveals how the pathogen utilizes calcium-dependent lectin for binding to human sugars.
tinyurl.com/243xbhbt
#glycotime
22 days ago
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reposted by
Marcin Czerwinski
Timothy Snyder
22 days ago
If we made the green energy transition this war would be unthinkable and these authoritarians wouldn’t be in power — not in the US, not in Iran, not in Saudi Arabia, not in Russia. Hydrocarbons are killing our freedom and just plain killing us.
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Stallhof, Residenzschloss, Dresden, Germany. 📷Minolta X-300 🔘28 mm 🎞️Ilford FP4+
#BelieveInFilm
23 days ago
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Warsaw, Evangelic Reformed Cemetery. Canon EOS 5, 70-300 mm, Ilford FP4+.
26 days ago
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Łukasz Lamża o piszczeniu butów, jak AI radzi sobie w fizyce i układzie nerwowym żebropława (od 22.22).
@pawelburkhardt.bsky.social
www.youtube.com/watch?v=gIp4...
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Zagadka piszczących butów - ChatGPT rozwija fizykę - Móżdżek żebropława | Czytamy naturę #283
YouTube video by Copernicus
https://www.youtube.com/watch?v=gIp4w70wPyE
27 days ago
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Warsaw, Staszic Square with the Kopernik monument. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford FP4+
#BelieveInFilm
about 1 month ago
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Another great paper from
@pawelburkhardt.bsky.social
about the subepithelial nerve net (SNN) in ctenophores: it forms synaptic connections with effector cells (some 17 cell types). The signal processing within the aboral organ relies on synaptic and nonsynaptic communication.
tinyurl.com/2j5ud64m
about 1 month ago
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Under certain stress conditions, bacteria accumulate polyphosphate (polyP), which interacts with a long variant of CobB deacetylase, triggering a regulatory coupling to prevent DNA replication initiation
tinyurl.com/2cu8cnx8
about 1 month ago
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reposted by
Marcin Czerwinski
Pawel Burkhardt
about 1 month ago
Even more excited — our paper is featured on the cover of Science Advances! Huge thanks to
@alexandrejan.bsky.social
who took this incredible photo of a ctenophore (aka comb jelly) and the editors. Here’s the cover 👇
www.science.org/doi/10.1126/...
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reposted by
Marcin Czerwinski
Marc Somssich
about 1 month ago
Another great article by
@mastroianni.bsky.social
on the current
#SciencePublishing
system. Don't publish with for-profit publishers like Elsevier, Springer Nature, et al. It's really simple. There are so many cool
#PlantScience
society journals.
#SciPub
See also:
bsky.app/profile/soms...
add a skeleton here at some point
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reposted by
Marcin Czerwinski
Elisa Fadda
about 1 month ago
Wee thread 🧵⬇️ on our new
#glycotime
with
@siglecdude.bsky.social
John Klassen and
@glycocode.bsky.social
🥳 where we show Siglecs as molecular precision tools, able to recognise sialylated glycans with surgical precision in their natural environment, not bad for a lectin! 😎
doi.org/10.1038/s420...
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B4GALNT3, an enzyme that synthesizes GalNAcβ1-4GlcNAc, contains a unique non-catalytic PA14 domain, which is a lectin domain recognizing sulfated glycans (eg. Gal[6S]β1-4GlcNAc[6S]). Such sulfated glycans negatively regulate the PA14-dependent catalytic activity.
tinyurl.com/3zymxxdh
#glycotime
about 1 month ago
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Fucosylation inhibits pertussis toxin binding to the cell surface, while sialylation and N-linked glycosylation promote the binding, resulting in increased intracellular ERK phosphorylation
tinyurl.com/bdza4j38
#glycotime
about 1 month ago
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reposted by
Marcin Czerwinski
Elisa Fadda
about 1 month ago
Alpha-Gal syndrome ⤵️🟡 sad
#glycotime
😞
add a skeleton here at some point
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All you ever wanted to know about clinical gene therapy for hemophilia and globin disorders: in vivo and ex vivo methods, lentiviral and adeno-associated viral (AAV) vectors, and gene silencing by the CRISPR-Cas9 gene editing system.
@rkaczmarekdr.bsky.social
tinyurl.com/3yctsr5a
#hemophilia
about 1 month ago
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reposted by
Marcin Czerwinski
Steve Haddock
about 1 month ago
Calling all
#ctenophore
researchers and artists! Joe Ryan is organizing the Ctenopalooza Ctwo meeting, which we will host at MBARI in California August 23-25. 🦑🧪🌊
www.mbari.org/event/ctenop...
Come swap notes with fellow enthusiasts about the latest news in comb jellies.
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Jaki związek mogą mieć antygeny układu grupowego krwi P1PK z bąblowicą? Moje uwagi na blogu
eksperymentmyslowy.pl
tinyurl.com/24h5nh5k
about 1 month ago
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Moje uwagi na temat "Solaris" Stanisława Lema: dlaczego ta książka jest ciągle aktualna?
tinyurl.com/5dk5786v
about 2 months ago
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Rail line Opole-Kluczbork with the rail bus SA103 approaching Kały station. 📷Canon EOS 5 🔘70-300 mm 🎞️Ilford FP4+
#BelieveInFilm
about 2 months ago
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Now this is big: under freezing conditions, a small polymerase ribozyme called Q45 can synthesize itself and its complementary strand. It seems that life might have started in the cold: Earth’s natural freeze-thaw cycles may have helped concentrate life’s building blocks.
tinyurl.com/36tnesn5
about 2 months ago
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Wrocław, Kępa Mieszczańska. 📷Minolta X-300 🔘28 mm 🎞️Ilford Delta 100
#BelieveInFilm
#Turpism
about 2 months ago
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reposted by
Marcin Czerwinski
Fabio Chiusi
about 2 months ago
“The richest man in the world posted about how the white race was under threat, made allusions to race science or promoted anti-immigrant conspiracy content on 26 out of 31 days in January”
www.theguardian.com/technology/2...
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Elon Musk posted about race almost every day in January
Many social media posts by Tesla CEO on his platform are indiscernible from those of white supremacists, say experts
https://www.theguardian.com/technology/2026/feb/12/elon-musk-posts-january-white-supremacists
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reposted by
Marcin Czerwinski
Organic & Biomolecular Chemistry
about 2 months ago
🔓Don't miss this
#OpenAccess
review from Dominik Weh &
@delbiancom.bsky.social
at
@mpici.bsky.social
in our latest issue looking at how mirror-image glycans can be leveraged to tailor carbohydrate materials Check it out in full on our website🔽
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Leveraging mirror-image glycans in carbohydrate materials
Chirality has become a fundamental design principle to craft peptide materials. In contrast, the systematic exploitation of chirality to build glycan materials remains largely unexplored, despite the…
https://pubs.rsc.org/en/content/articlelanding/2026/ob/d5ob01778e
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Murów, opolskie voivodeship. Abandoned rail station. 📷Canon EOS 5 🔘70-300 mm 🎞️Ilford XP2
#BelieveInFilm
#Turpism
about 2 months ago
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Finally, a detailed review about C-mannosylation: mechanism of C-mannosyltransferases and the influence of the C-mannosylation on the function of several proteins. Highly recommended to everyone in this type of post-translational modification!
tinyurl.com/3ywjmfk3
#glycotime
about 2 months ago
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Zagwiździe, Opolskie voivodeship. 📷Canon EOS 5 🔘70-300 mm 🎞️Ilford XP2
#BelieveInFilm
about 2 months ago
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reposted by
Marcin Czerwinski
Jeremy Baskin
about 2 months ago
New paper in
@jcb.org
! We found a new regulator of p62 phase separation, autophagy, and antioxidant signaling. It is an E3 ligase adaptor called SHKBP1, but the effect is via direct p62 binding, not ubiquitination. Congrats to Lin Luan & team!
@weillinstitute.bsky.social
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"Jeden enzym, trzy antygeny, cztery fenotypy": moje uwagi o ludzkim układzie grupowym krwi P1PK na blogu
eksperymentmyslowy.pl
about 2 months ago
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Finally, an in-depth review
#JBC
about sialylation in cancer: dual role of sialyltransferases (the “writers”) and siglecs/selectins (the “readers”) in cancer progression. Must-read!
tinyurl.com/yvauu3zj
@mathd34.bsky.social
@siglecdude.bsky.social
#glycotime
about 2 months ago
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Where is coagulation factor VIII (FVIII) produced? After decades of research, the new data show that FVIII comes from liver sinusoidal endothelial cells located in zones 2 and 3 of hepatic lobules in mice and humans, with minimal expression in Zone 1
@rkaczmarekdr.bsky.social
tinyurl.com/ydtaar2a
about 2 months ago
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Can adeno-associated virus (AAV) gene therapies for hemophilia trigger tumorigenesis? Not really, as
@rkaczmarekdr.bsky.social
explains...
tinyurl.com/3wpfsw3p
#hemophilia
2 months ago
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Interesting preprint shows that P. vivax uses amplification of the PvDBP gene to avoid the hosts' anti-PvDBP immunity: the more inhibitory the Abs in the hosts’ plasma, the higher the proportion of multi-copy parasites.
tinyurl.com/57xdv7za
#malaria
2 months ago
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Stare Budkowice, Opolskie voivodeship. 📷Canon EOS 5 🔘70-300 mm 🎞️Ilford XP2
#BelieveInFilm
#Turpism
2 months ago
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Wrocław, Grabiszyn Park. 📷Bronica ETRS 🔘50 mm 🎞️Ilford HP5+
#BelieveInFilm
2 months ago
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The final version appeared today! Our paper on the expression of antigens belonging to the P1PK human blood group system in birds, and how they make them resistant to Shiga toxins.
tinyurl.com/bdv7zdaa
#glycotime
2 months ago
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reposted by
Marcin Czerwinski
Paula Ramiro-Martínez
2 months ago
New paper out in PNAS!!! 🎉 Do more plasmid copies mean faster evolution? 🧵 Dive into the story
www.pnas.org/doi/10.1073/...
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Plasmid mutation rates scale with copy number | PNAS
Plasmids are extrachromosomal DNA molecules that spread by horizontal transfer and shape bacterial evolution. Plasmids are typically present at mul...
https://www.pnas.org/doi/10.1073/pnas.2526088123
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Marcin Czerwinski
Oko.press RSS
2 months ago
„Pęka budowany z dużym wysiłkiem ład” – ostrzegają Ocalały z Auschwitz i dyrektor Muzeum [Wystąpienia] -
https://oko.press/peka-budowany-z-duzym-wysilkiem-lad-ostrzegaja-ocalaly-z-auschwitz-i-dyrektor-muzeum-wystapienia
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„Pęka budowany z dużym wysiłkiem ład” – ostrzegają Ocalały z Auschwitz i dyrektor Muzeum [Wystąpienia]
"Widzę przemoc, która znów zaczyna być usprawiedliwiana. Widzę ludzi, którzy wierzą, że ich gniew ma wartość większą niż życie drugiego człowieka" -ostrzega ocalały z Auschwitz 97-letni Bernard Offen. "Pęka budowany z dużym wysiłkiem ład, a prawo międzynarodowe jest gwałcone" - ostrzega dyrektor Muzeum Auschwitz Piotr Cywiński w 81. rocznicę wyzwolenia obozu
https://oko.press/peka-budowany-z-duzym-wysilkiem-lad-ostrzegaja-ocalaly-z-auschwitz-i-dyrektor-muzeum-wystapienia
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