Happy new year everyone, this time last year I was looking forward to some winter sun in South Africa at the @BMSV conference. That same feeling would be welcome now!

Ah ha, as I suspect: there is an unequal distribution of the contents of a celebrations tub! Bluesky do your things and help in this scientific study!

We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development. www.nature.com/articles/s41... A thread.

Well that’s another Christmas gift! Great collaboration between Tim Dafforn at Bhm Biosciences & Phil Ireland at DSTL and the wonderful student Adam (drive cruser) Evans dx.doi.org/10.1002/pro....

Fantastic to be part of this which was published today, Dr Nic Briggs and newly minted Dr Jack Stone from my lab did the experimental works that contributed to the paper with Christophe Grangeasse and colleagues. @warwicklifesci.bsky.social

Just got word that we are a go for the Bacterial Cell Biology and Development GRS and GRC at Southern New Hampshire University! GRS will be on June 5-6, 2027 GRC will be from June 6-11, 2027 Block off your calendars Prokaryotic Cell Biologists! More details to come! Please repost!

Google at its peak was basically the best information retrieval system in human history and they and every competitor decided going from there to “you didn’t want answers you wanted half-assed auto-complete 80%-wrong hallucinations” in a few years was the right idea

A very - ahem - groovy talk by @georgiaisom.bsky.social: the protein YhdP spans the E. coli periplasm and transports phospholipids to the OM via a hydrophobic groove along its length. Impressive mix of computational & wet lab work www.sciencedirect.com/science/arti...

Kate Willett pass her viva yesterday, congrats Dr Willett! Huge thanks to @robfagan.bsky.social @ @jeremykeown.bsky.social

I think young Professor Tame had a good time with us @warwicklifesci.bsky.social curtesy of an IAS professorial fellowship and is now of on the second leg in Rome. Thanks to my lab for making home feel so welcome. I may have to visit him in Rome, just to make sure he’s ok of course…

JB Editor's Choice: Anderson, Khursigara et al. review the role of peptidoglycomics in understanding the structure and function of peptidoglycan. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology

Excited to share my latest postdoctoral work in the Shen Lab at Tufts! In this study, we follow up on an exciting finding by former grad student @shailab.bsky.social that C diff uses its Class A PBP (PBP1) to drive cell division (unlike previously studied bacteria)! journals.plos.org/plosgenetics...

30 years on since @YSBL_York who would have thought these two old gits would find themselves in a lab together again!

Looking for a PhD? 🚀 MIBTP projects are out lots to explore! 🔬 #Bacteria • #AMR • #Interdisciplinary • FUN! My projects explore how Gram-negative bacteria build and maintain their three-layered cell envelope, using cryo-EM, fluorescence microscopy and biochemistry. warwick.ac.uk/fac/cross_fa...

Just in time for Becca’s thesis submission, their paper on MreB membrane interactions is published in @biophysj.bsky.social: www.cell.com/biophysj/ful... 🎉

I joined School of Life Sciences 3 months ago and these guys have been so welcoming. Gibbet Hill Rovers making it feel like being apart of a community instantly. Thanks to @davidroper2.bsky.social for helping me get involved. Looking forward to season 3!

People get special things engraved…. We got cryo-EM pucks engraved. Now time to make some samples @jeremykeown.bsky.social

Great opportunity to do a PhD with Giusy and co in Glasgow!

Anyone else had a circuit board blow on a Sorval ultracentrifuge in the recent past?

Two PhD theses submitted to day from @warwicklifesci.bsky.social Kate Willett from my lab and Becca Bailey from @pstansfeld.bsky.social. Supervisor of one, internal examiner for another!

New from Chris Sham at NUS www.science.org/doi/10.1126/...

Lovely trip back to @UniOfYork to the carbohydrate group meeting of the @RoySocChem. Old friends and familiar places

It’s been my honour and privilege to co-organise the Great Wall Symposium with @ivo-boneca.bsky.social for the past 14 years, roll on 2027 more news soon.

And that’s a wrap on the Great Wall Symposium 2025! Roll on 2027, venue to be confirmed shortly …

Want to know what natural products are in clinical trials? Read this review! Great job from Mark Butler, Rob Capon, Mark Blaskovich! pubs.rsc.org/en/content/a... #naturalproducts #antibiotic #amr #drugdiscovery #drug

ICYMI: Simplifying access to MRC applicant-led funding #MRC #AcademicSky

And we are off! Professor Tame of Yokohama City University starts his first experiment as part of his sabbatical thanks to an IAS fellowship here

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

How it’s started, how it’s going …

Dear Bluesky, some good news to brighten your day! We are recruiting for the Director of the Centre for Population and Disease Genomics!! I would be grateful if you could share across your networks! uq.wd3.myworkdayjobs.com/uqcareers/jo...

Archaea are often surrounded by bacteria. But is there ever active conflict between the two? Can archaea kill bacteria? If so, how do they do it? Work by @romainstrock.bsky.social shows that some archaea can kill bacteria by secreting peptidoglycan hydrolases. journals.plos.org/plosbiology/...

Latest study with the super-human friend that is Zong. Gen epi of carbapenemase-producing Enterobacter in China. Lots of within and between hospital spread and increasing in incidence journals.asm.org/doi/10.1128/...

Professors Roper and Tame visited Hadrians wall today and contemplated the eternal philosophical question of “what did the romans….”🤣

'UK recovers position in EU’s Horizon Europe science research programme' search.app/VtjVD

#NewResearch Streptomyces use both polar and dispersed cell wall synthesis during rapid, exploratory growth @mcmasteriidr.bsky.social #BacteriaCellWall #MicroSky 🦠 www.nature.com/articles/s41...

Professors Roper and Tame up a hill in Yorkshire, grand…

A remarkable paper. Davisson and colleagues describe an in vitro reaction running under plausible prebiotic conditions that efficiently and stereoselectively aminoacylates a model tRNA. This suggests a path through which nature may have chosen L vs. D amino acids! www.biorxiv.org/content/10.1...

I've found that one of the best ways to resist attacks on science is to continue doing science. To that end, here's my new preprint studying the differences between type ii topoisomerases, some of the best targets for antibacterials, to help guide the development of new and better antibacterials 🧪

Just thinking about my September plans.. Anyone else..? Just sayin...

Charlie Mo: generic trade off in phage resistance leads to betalactam susceptibility and down-regulation of virulence genes in phage-resistant #MRSA strains #phages2025 🦠 elifesciences.org/articles/102...

Vaccines have helped to control many diseases that caused widespread suffering in the past, and continue to do so to this day. Professor of Immunology Charles Bangham FRS explains why we know #vaccines work and why they are so effective: royalsociety.org/blog/2021/01...

I was delighted to @UHCW path labs today to give a talk on our works and perspective on b-lactam usage and discuss with Steven Montgomery-Laird and colleagues, future collaborations and interactions @WarwickLifeSci @BMSatWarwick & Institute of Translational Medicine.

Today is World NTM awareness day (worldntmday.org) so timely to announce a collaboration between Professor Bavesh Kana at the University of the Witwatersrand. Charis Thompson in my lab works on a linkage between ST kinases and the control of peptidoglycan cross linking chemistry in NTMs.

Dr Gillett dons the ceremonial robes yesterday to get her degree certificate @uni-of-warwick.bsky.social Dr Cheng managed to look at the camera for a change..

Andrew Harvey former Warwick Biochemistry student and now Global Marketing Director @pfizer (boy did well..) came to @uniofwarwick to speak and inspire at the graduation ceremony for @WarwickLifeSci graduates. Great to see you again!

Phil Stansfeld and I played host to Dr Chandra Verma @ASTARsg former collegue of mine from @YSBL_York visits @WarwickLifeSci & @BMSatWarwick today to tell us about developments in the institute and research in his group. If only he could stay longer for an international fiesta, old style !

I’m seeing LinkedIn posts from former Venatorx employees laid off of July 4th. Anyone know what’s going on?

journals.plos.org/plosgenetics... It was fun to have contributed to this nice work from @crodrigueslab.bsky.social

India, through C-CAMP, has launched the #OneHealth #AMR Challenge 2025, to fund innovators and startups developing technologies to tackle AMR across human, animal, and environmental health. Supported by #ICARS, the initiative will help address the annual toll of AMR. theprint.in/science/govt...

Another victory for Gibbet Hill Rovers, 1 - nil against statistics @WarwickLifeSci @warwickmed @uniofwarwick