We are looking for a postdoc to join our team! If you're interested in translating a cutting edge genomics technology (www.nature.com/articles/s41...) to real-life applications in hematology, this is for you. We offer a unique working environment ON THE BEACH: recruitment.crg.eu/content/jobs...

We have an exciting PhD opportunity through the EASTBIO programme, co-supervised with Diego Oyarzún. This project combines synthetic and systems biology to uncover the gene-regulatory circuitry hijacked in a cancer model. We’re looking for candidates with a strong interest in functional genomics.

I'm a longtime fan of Affinity Designer as an affordable Illustrator-killer for figures, and... it's now free?! www.canva.com/newsroom/new... Highly recommended if you're sick of paying Adobe $. Maybe Canva can buy NPG too and get rid of the OA fees.

📣Job Opportunity: Develop machine learning of cellular automata models with applications to in vitro developmental biology. More info: edin.ac/49Mr7ZQ

Congratulations @nsbenab.bsky.social and fellow experts joining the Independent Scientific Advisory Panel! 👏 @cmvm-edinburghuni.bsky.social

Beautiful (jaw-dropping 😉) work from Hannah Long’s group revealing how Neandertal enhancers influence facial morphology!

I guess I need to apologize to the writers of Alien: Prometheus. it turns out scientists really do touch everything like that

🥁This Wednesday , in #FragileNucleosome seminar, we are excited to host @hannahlong.bsky.social and @jeffvierstra.bsky.social to tell us about amazing work they are doing! 🗓️Register here for upcoming session and the entire series: us06web.zoom.us/webinar/regi...

Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one? Check our latest preprint, led by @mmasoura.bsky.social, to find out! www.biorxiv.org/content/10.1...

What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters www.biorxiv.org/content/10.1...

Programmable promoter editing for precise control of transgene expression - @mitcheme.bsky.social @mitdeptofbe.bsky.social go.nature.com/4h9wlR1

🦖 Something HUGE just hatched. Plasmidsaurus now offers RNA sequencing for gene expression analysis: • As fast as 3 day turnaround • $50/sample for academia, $80 for industry • Up to ~10M unique transcript 3’ end reads per sample • Interactive results Explore Plasmidsaurus RNA-Seq today.

If you’re interested in exploring the relationship between chromatin organization and epigenetic memory using chromatin tracing microscopy, my group is recruiting a talented PhD student 🥳

🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China

And look at this graphic abstract….. 😱🤯

'Innovation does not occur in a vacuum. It requires raw materials: the findings of basic research. We are currently burning through a stockpile of knowledge accumulated during a more enlightened era of public investment, while allocating insufficient resources for replenishing it.'

Fascinating!

Lancet editor: "I can’t forgive Bhattacharya and Makary...both know reliable evidence does not exist to restrict paracetamol use during pregnancy...both know evidence linking vaccines to autism simply doesn't exist. What are they doing?" [politics - that's what] www.thelancet.com/action/showP...

Hot off the press! Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4 www.nature.com/articles/s41...

For #BreastCancerAwarenessMonth, @lesleys20.bsky.social is taking part in a @cancerresearchuk.org seminar exploring the challenges of experiencing cancer in a personal capacity while working in cancer research. Sign up for the seminar: edin.ac/4gRvvZl and read her story here: edin.ac/4741m5y

Wonderful meeting @embl.org to celebrate the amazing career of #AnneEphrussi 👏🎉🤟

By focusing research on either ‘adult cancer’ or ‘childhood cancer’, we risk excluding teenagers and young adults (TYA). We need to treat TYA patients as a distinct subpopulation that straddles paediatric and adult cancer services.

We have space for two postdoctoral fellows in the Taipale Lab at the @sangerinstitute.bsky.social. This is a core-funded open position! Come with your ideas and interests and we can develop a project together. sanger.wd103.myworkdayjobs.com/en-US/Wellco...

Great opportunity! Up to 4 Group Leader positions at the NOVA Institute for Medical Systems Biology (NIMSB) in Computational & Experimental Medical Systems Biology 📍 Lisbon ⏳ Apply by Oct 8 🔗 nimsb.unl.pt/wp-content/u... #Job #SciencePositions #JobOffer #GroupLeaders #Innovation #systemsbiology

Join @cmaley.bsky.social, @lucielaplane.bsky.social, Joel Brown and Benjamin Spada for a live EvoChat discussion about "How we define cancer matters", hosted by the International Society for Evolution, Ecology and Cancer (ISEEC). Oct 1st at 8am PST, 11am EST, 5pm CEST ucsb.zoom.us/j/8313111375...

This is a disaster if the EU doesn't follow up by doubling the budget 😬🧪

The scent of silence! Cool research in Cell @cellpress.bsky.social to brighten up your day🌹. The mystery of why some roses are fragrant and others aren't has an answer. It's called SCREP: a rose-specific gene that evolved from non-coding DNA 16.8 million years ago 👇

Still two weeks left to apply to the #postdoc position in my lab via the @dkfz.bsky.social fellowship program. #epigenomics #hematology #leukemia #computationalbiology #precisiononcology

This is not a HiC map! Ever wondered if multiple enhancers get activated simultaneously? We measured chromatin accessibility on thousands of molecules by nanopore to create genome-wide co-accessibility maps. Proud of @mathias-boulanger.bsky.social @kasitc.bsky.social Biology in the thread👇

Domain analysis identifies a discrete nucleic acid-binding domain (NBD) within SUZ12 responsible for constraining PRC2 activity. CryoEM studies showed the NBD in close proximity to nucleic acids. Loss of this region (NEC, VEFS) causes global H3K27me3 hypermethylation. 11/13

simply wonderful science 🤩

I’m happy to share our published work in @cp-cellreports.bsky.social! With zebrafish modeling of rhabdomyosarcoma, we showed that PAX3::FOXO1 utilizes homeobox motif recognition to initially bind closed DNA and activate neural programs present in the human disease. www.cell.com/cell-reports...

📢 We are recruiting! Several projects are available and can be tailored to the candidate's profile. Most include confocal imaging/spatial OMICs technologies. Please share and RT 🙏

Another paper bluetorial! Today: how does the spatial location of genes influence their function? (1/n) www.nature.com/articles/s41...

Very excited to share the first preprint of the lab! We show that the nuclear pore protein TPR forms biomolecular condensates which keep heterochromatin away from the nuclear pore complexes and maintains global chromatin organization. Check it out, share it, tell us what you think!!

Once a surfer's paradise, a string of deadly attacks made Réunion Island synonymous with one word only: sharks. But a team of scientists turned this tiny island into a hub of lifesaving research. For @science.org, I wrote about this fascinating place. www.science.org/content/arti...

Happy to share our recent publication on benchmarking peak calling methods for CUT&RUN. academic.oup.com/bioinformati... Published in @oxunipress.bsky.social Bioinformatics | led by aminnoorani.bsky.social #Epigenomics #Genomics #Bioinformatics #MachineLearning #CUTandRUN #CompBio #4DNucleome

Excited to share our hot-off-the-press @biorxivpreprint.bsky.social that explores how PRC1-mediated H2AK119ub deposition safeguards lineage fidelity during forebrain development. Fantastic work by @lucyadoyle.bsky.social and our colleagues & collaborators. 🥳🧬🧠🔬 www.biorxiv.org/content/10.1...

Why choose the Vienna BioCenter - Hear it directly from our fellows! The VIP³ call is open – 16 fully-funded, three-year postdoctoral fellowships in an interdisciplinary environment: training.vbc.ac.at/post-docs/vi... #VBCPostDoc

Excited to share the lab's 1rst preprint! Rapid high-res immunofluorescence is now possible in cultured & environmental diatoms thanks to 4-fold expansion microscopy. A step-change for comparative cell biology in one of the most important phytoplankton groups on the planet 🥳 tinyurl.com/m9s5su7s 1/2

EPIGENETIC HULK READY TO SMASH AGAIN! GET IN LOSERS!

🎉 Congrats to our scientists at The Scotland Institute on their publication in the Journal of Medicinal Chemistry! They’ve developed reversible Ras inhibitors with tunable affinity for active & inactive forms, a big step in #DrugDiscovery. More: tinyurl.com/y45t4yy7 #OnMyHorizon @acs.org

Nice work from Du & Warmflash using micropatterned hESCs to dissect midbrain-hindbrain boundary formation Timing of WNT signalling, not strength or duration, specifies midbrain-hindbrain boundary Good example of recapitulating developmental signalling in vitro www.biorxiv.org/content/10.1...

We are highlighting Pleasantine Mill, 2025 @bsdb.bsky.social Wolpert Medal winner, as an extraordinary biologist this week. Pleasantine is also coordinating a @jcellsci.bsky.social Special Issue and co-organised the 2024 @dmmjournal.bsky.social‬ Journal Meeting. #100biologists @cilialab.bsky.social

Robust statistical assessment of Oncogenotype to Organotropism translation in xenografted zebrafish www.biorxiv.org/content/10.1... #sarcoma

Under pressure archaea develop tissue-like multicellularity! Fascinating! 👉🏻https://www.science.org/doi/10.1126/science.adu0047

This morning, at #ASCO25 in Chicago, Professor Robin Jones presents an oral session on advanced #Sarcoma ⬇️ meetings.asco.org/abstracts-pr...

Thanks to phenomenal work by @crg.eu and @irbbarcelona.org press offices, we got to communicate our findings on 🧬 methylation barcodes and 🩸 blood ageing to a wide audience. A cool experience! 🧵 with highlights in 5 languages and funny moments 😬😅 cadenaser.com/nacional/202... (1/n)

We were up and shining up on the stage at the “Impact Festival” yesterday 🐟🐟🐟🎉🎉🎉🤩🤩 Thank you for the nomination 🥰 Go Fish !

Expansion microscopy 🤩