Roberto Vázquez Núñez (@robertovn.bsky.social)

Cell-free genomics reveals fundamental regulatory principles of the Mycobacterium tuberculosis transcription cycle Froom et al. address a central challenge in gene regulation: untangling direct effects from indirect cellular network effects. They introduce cell-free genomics, a genome-scale biochemical approach that isolates direct transcription mechanisms. Applied to Mycobacterium tuberculosis, it reveals fundamental principles of transcription initiation and termination with broad relevance. http://dlvr.it/TR74db